DE69104203D1 - Verfahren und gerät zur messung des blut-glukose-gehaltes in vivo. - Google Patents

Verfahren und gerät zur messung des blut-glukose-gehaltes in vivo.

Info

Publication number
DE69104203D1
DE69104203D1 DE69104203T DE69104203T DE69104203D1 DE 69104203 D1 DE69104203 D1 DE 69104203D1 DE 69104203 T DE69104203 T DE 69104203T DE 69104203 T DE69104203 T DE 69104203T DE 69104203 D1 DE69104203 D1 DE 69104203D1
Authority
DE
Germany
Prior art keywords
chambers
substance
vivo
infrared light
measuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69104203T
Other languages
English (en)
Other versions
DE69104203T2 (de
Inventor
Vaughan Clift
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE69104203D1 publication Critical patent/DE69104203D1/de
Application granted granted Critical
Publication of DE69104203T2 publication Critical patent/DE69104203T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69104203T 1990-06-06 1991-06-06 Verfahren und gerät zur messung des blut-glukose-gehaltes in vivo. Expired - Fee Related DE69104203T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPK048990 1990-06-06
AUPK431091 1991-01-22
PCT/DK1991/000152 WO1991018548A1 (en) 1990-06-06 1991-06-06 Method and device for in vivo measuring blood sugar levels

Publications (2)

Publication Number Publication Date
DE69104203D1 true DE69104203D1 (de) 1994-10-27
DE69104203T2 DE69104203T2 (de) 1995-01-19

Family

ID=25643880

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69104203T Expired - Fee Related DE69104203T2 (de) 1990-06-06 1991-06-06 Verfahren und gerät zur messung des blut-glukose-gehaltes in vivo.

Country Status (5)

Country Link
EP (1) EP0536187B1 (de)
JP (1) JP3212996B2 (de)
AT (1) ATE111706T1 (de)
DE (1) DE69104203T2 (de)
WO (1) WO1991018548A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
SE9500893D0 (sv) * 1995-03-13 1995-03-13 Synectics Medical Ab Förfarande och system för bestämning av substanssammansättning jämte ambulatoriskt registreringssystem
US6614522B1 (en) 1995-09-08 2003-09-02 Integ, Inc. Body fluid sampler
US6624882B2 (en) 1995-09-08 2003-09-23 Integ, Inc. Methods of sampling body fluid
AU7015096A (en) * 1995-09-08 1997-04-09 Integ, Inc. Body fluid sampler
US5879367A (en) 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
US5891022A (en) * 1996-09-25 1999-04-06 Ohmeda Inc. Apparatus for performing multiwavelength photoplethysmography
DE19758531C2 (de) 1996-10-30 2003-06-05 Amira Medical Scotts Valley Synchronisiertes Analyt-Testsystem
JP4212007B2 (ja) * 1996-11-26 2009-01-21 パナソニック電工株式会社 血液成分濃度の分析装置
JP4163853B2 (ja) 1997-08-09 2008-10-08 ロシュ ダイアグノスティックス ゲーエムベーハー 患者の身体におけるｉｎｖｉｖｏ分析用の分析装置
US5941821A (en) * 1997-11-25 1999-08-24 Trw Inc. Method and apparatus for noninvasive measurement of blood glucose by photoacoustics
DE19858426C2 (de) * 1997-12-17 2002-01-31 Steffen Leonhardt Vorrichtung zur Messung des menschlichen Blutzuckerspiegels
US6226082B1 (en) 1998-06-25 2001-05-01 Amira Medical Method and apparatus for the quantitative analysis of a liquid sample with surface enhanced spectroscopy
US6120464A (en) * 1998-10-16 2000-09-19 Integ, Inc. Needle assembly for fluid sampler
US6368563B1 (en) 1999-03-12 2002-04-09 Integ, Inc. Collection well for body fluid tester
JP3594534B2 (ja) 1999-04-30 2004-12-02 ヘルマン ファウ、リリエンフェルトアル 物質を検出する装置
DE59913262D1 (de) 1999-07-08 2006-05-11 Leonhardt Steffen Vorrichtung zur messung des menschlichen blutzuckerspiegels
US7050157B2 (en) * 2001-11-08 2006-05-23 Optiscan Biomedical Corp. Reagent-less whole-blood glucose meter
EP1585440A1 (de) * 2003-01-13 2005-10-19 Glucon Inc. Photoakustische prüfungsmethode und vorrichtung
WO2005007215A2 (en) 2003-07-09 2005-01-27 Glucolight Corporation Method and apparatus for tissue oximetry
WO2005027746A1 (ja) * 2003-09-22 2005-03-31 Matsushita Electric Industrial Co., Ltd. グルコース濃度測定方法及びグルコース濃度測定装置
US7510849B2 (en) 2004-01-29 2009-03-31 Glucolight Corporation OCT based method for diagnosis and therapy
US7254429B2 (en) 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
US8036727B2 (en) 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
JP2008537903A (ja) 2005-04-13 2008-10-02 グルコライト・コーポレーシヨン Ｏｃｔが基になった血糖モニターのデータ処理および較正方法
CN101336371B (zh) 2006-06-08 2012-02-01 欧姆龙健康医疗事业株式会社 可高精度非侵入地计测生物体成分的生物体成分计测装置
JP2008026036A (ja) * 2006-07-18 2008-02-07 Aloka Co Ltd 含有物測定装置
ATE492796T1 (de) * 2006-09-20 2011-01-15 Prad Res & Dev Nv Vorrichtung und verfahren zur optischen ermittlung der anwesenheit von kohlendioxid
JP2008275383A (ja) * 2007-04-26 2008-11-13 Hitachi Engineering & Services Co Ltd 混合成分系の濃度測定方法及び装置、及びその装置を用いた省エネルギー或いは排気浄化設備の運転制御システム。
CN101910825B (zh) * 2008-01-03 2014-04-23 皇家飞利浦电子股份有限公司 生物传感器中的消逝场调制
US8571617B2 (en) 2008-03-04 2013-10-29 Glt Acquisition Corp. Flowometry in optical coherence tomography for analyte level estimation
US8221346B2 (en) 2008-04-24 2012-07-17 Arkray, Inc. Blood sugar level control system
DE102015007871B4 (de) * 2014-08-09 2022-10-20 SAMTD GmbH & Co. KG Verfahren und Vorrichtung zur nicht-invasiven Bestimmung einer Messgröße eines Analyten in einem biologischen Körper
CN108872082B (zh) * 2018-04-03 2021-03-02 深圳大学 光声显微成像系统及方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934190A1 (de) * 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
US4509522A (en) * 1981-12-15 1985-04-09 The United States Of America As Represented By The Secretary Of The Navy Infrared optical measurement of blood gas concentrations and fiber optic catheter
US4655225A (en) * 1985-04-18 1987-04-07 Kurabo Industries Ltd. Spectrophotometric method and apparatus for the non-invasive
US4882492A (en) * 1988-01-19 1989-11-21 Biotronics Associates, Inc. Non-invasive near infrared measurement of blood analyte concentrations

Also Published As

Publication number Publication date
ATE111706T1 (de) 1994-10-15
JP3212996B2 (ja) 2001-09-25
WO1991018548A1 (en) 1991-12-12
EP0536187B1 (de) 1994-09-21
JPH05507866A (ja) 1993-11-11
DE69104203T2 (de) 1995-01-19
EP0536187A1 (de) 1993-04-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee