DE69102352D1 - N-Benzyl-N1-phenyl und -phenalkyl-thioharnstoffe. - Google Patents

N-Benzyl-N1-phenyl und -phenalkyl-thioharnstoffe.

Info

Publication number
DE69102352D1
DE69102352D1 DE69102352T DE69102352T DE69102352D1 DE 69102352 D1 DE69102352 D1 DE 69102352D1 DE 69102352 T DE69102352 T DE 69102352T DE 69102352 T DE69102352 T DE 69102352T DE 69102352 D1 DE69102352 D1 DE 69102352D1
Authority
DE
Germany
Prior art keywords
5alkyl
hydrogen
substituted
phenalkyl
thioureas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69102352T
Other languages
English (en)
Other versions
DE69102352T2 (de
Inventor
Christopher Simon John Walpole
Roger Wrigglesworth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909013575A external-priority patent/GB9013575D0/en
Priority claimed from GB909013953A external-priority patent/GB9013953D0/en
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Publication of DE69102352D1 publication Critical patent/DE69102352D1/de
Application granted granted Critical
Publication of DE69102352T2 publication Critical patent/DE69102352T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69102352T 1990-06-18 1991-06-17 N-Benzyl-N1-phenyl und -phenalkyl-thioharnstoffe. Expired - Fee Related DE69102352T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909013575A GB9013575D0 (en) 1990-06-18 1990-06-18 Improvements in or relating to organic compounds
GB909013953A GB9013953D0 (en) 1990-06-22 1990-06-22 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
DE69102352D1 true DE69102352D1 (de) 1994-07-14
DE69102352T2 DE69102352T2 (de) 1994-11-17

Family

ID=26297217

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69102352T Expired - Fee Related DE69102352T2 (de) 1990-06-18 1991-06-17 N-Benzyl-N1-phenyl und -phenalkyl-thioharnstoffe.

Country Status (17)

Country Link
EP (1) EP0462933B1 (de)
JP (1) JPH0753708B2 (de)
KR (1) KR920000715A (de)
AT (1) ATE106866T1 (de)
AU (1) AU645090B2 (de)
CA (1) CA2044797A1 (de)
CS (1) CS185091A3 (de)
DE (1) DE69102352T2 (de)
DK (1) DK0462933T3 (de)
ES (1) ES2054474T3 (de)
FI (1) FI912903A (de)
HU (1) HU210683B (de)
IE (1) IE912055A1 (de)
IL (1) IL98522A0 (de)
NZ (1) NZ238571A (de)
PL (1) PL290703A1 (de)
PT (1) PT98004A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9519270D0 (en) * 1995-09-21 1995-11-22 Sandoz Pharma Uk Organic compounds
JP2002531545A (ja) * 1998-12-09 2002-09-24 ワイス ヘルペスウイルスのチオ尿素インヒビター
US6255349B1 (en) 1998-12-09 2001-07-03 American Home Products Corporation Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
US6207715B1 (en) 1998-12-09 2001-03-27 American Home Products Corporation Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
PT1137645E (pt) * 1998-12-09 2004-09-30 Wyeth Corp Inibidores virus de herpes a base de tioureia alfa-metilbenzilada contendo um grupo fenilenodiamina
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
MXPA03001535A (es) 2000-08-21 2004-12-13 Pacific Corp Derivados de tiourea novedosos y las composiciones farmaceuticas que contienen los mismos.
WO2002016319A1 (en) * 2000-08-21 2002-02-28 Pacific Corporation Novel thiourea compounds and the pharmaceutical compositions containing the same
TWI239942B (en) 2001-06-11 2005-09-21 Dainippon Pharmaceutical Co N-arylphenylacetamide derivative and pharmaceutical composition containing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4460602A (en) * 1981-06-30 1984-07-17 The Procter & Gamble Company Urea derivatives
ES2061624T3 (es) * 1987-03-09 1994-12-16 Procter & Gamble Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.
GB8715357D0 (en) * 1987-06-30 1987-08-05 Sandoz Inst For Medical Resear Organic compounds
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
AU645090B2 (en) 1994-01-06
NZ238571A (en) 1993-08-26
JPH04230257A (ja) 1992-08-19
HU911862D0 (en) 1991-12-30
FI912903A0 (fi) 1991-06-14
FI912903A (fi) 1991-12-19
EP0462933B1 (de) 1994-06-08
EP0462933A1 (de) 1991-12-27
KR920000715A (ko) 1992-01-29
PT98004A (pt) 1992-03-31
HU210683B (en) 1995-06-28
IE912055A1 (en) 1991-12-18
HUT59090A (en) 1992-04-28
PL290703A1 (en) 1992-09-21
ATE106866T1 (de) 1994-06-15
ES2054474T3 (es) 1994-08-01
CS185091A3 (en) 1992-01-15
AU7843891A (en) 1991-12-19
DK0462933T3 (da) 1994-08-15
JPH0753708B2 (ja) 1995-06-07
DE69102352T2 (de) 1994-11-17
CA2044797A1 (en) 1991-12-19
IL98522A0 (en) 1992-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee