DE69032797D1 - Avermectin-Derivate - Google Patents

Avermectin-Derivate

Info

Publication number
DE69032797D1
DE69032797D1 DE69032797T DE69032797T DE69032797D1 DE 69032797 D1 DE69032797 D1 DE 69032797D1 DE 69032797 T DE69032797 T DE 69032797T DE 69032797 T DE69032797 T DE 69032797T DE 69032797 D1 DE69032797 D1 DE 69032797D1
Authority
DE
Germany
Prior art keywords
avermectin derivatives
substituted
ketoximes
derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69032797T
Other languages
English (en)
Other versions
DE69032797T2 (de
Inventor
Bruce O Linn
Helmut Mrozik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE69032797D1 publication Critical patent/DE69032797D1/de
Application granted granted Critical
Publication of DE69032797T2 publication Critical patent/DE69032797T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69032797T 1989-07-31 1990-07-31 Avermectin-Derivate Expired - Fee Related DE69032797T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,207 US5023241A (en) 1989-07-31 1989-07-31 Avermectin derivatives

Publications (2)

Publication Number Publication Date
DE69032797D1 true DE69032797D1 (de) 1999-01-14
DE69032797T2 DE69032797T2 (de) 1999-07-01

Family

ID=23528933

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69032797T Expired - Fee Related DE69032797T2 (de) 1989-07-31 1990-07-31 Avermectin-Derivate

Country Status (10)

Country Link
US (1) US5023241A (de)
EP (1) EP0411897B1 (de)
JP (1) JPH0826059B2 (de)
AT (1) ATE174033T1 (de)
AU (1) AU630992B2 (de)
CA (1) CA2022113A1 (de)
DE (1) DE69032797T2 (de)
IE (1) IE902752A1 (de)
NZ (1) NZ234685A (de)
ZA (1) ZA905996B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69310539T2 (de) * 1992-11-20 1998-01-15 British Tech Group Bildrekonstruktion
GB9300883D0 (en) * 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5411946A (en) * 1993-02-24 1995-05-02 Merck & Co., Inc. Avermectin derivatives
US5362862A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for 4"-EPI-acetylamino-4"-deoxy-5-oximinoavermectin-B1
US5420260A (en) * 1993-09-29 1995-05-30 Merck & Co., Inc. Process for 4"-epi-acetylamino-4"-deoxy-5-oximinoavermectin B1
ES2138090T3 (es) * 1993-10-05 2000-01-01 Pfizer Procedimiento e intermedios para doramectina.
US5535503A (en) * 1993-12-03 1996-07-16 Globe Products Inc. Stator lead wire connection method and apparatus
US5981500A (en) * 1994-01-12 1999-11-09 Pfizer Inc. Antiparasitic agents related to the milbemycins and avermectins
US5578581A (en) * 1994-04-26 1996-11-26 Merck & Co., Inc. Active avermectin analogue
CR6574A (es) * 2001-02-27 2004-10-28 Syngenta Participations Ag Sales de avermectinas substituidas en la posicion 4 con propiedades plaguicidas
EG23124A (en) * 2001-02-27 2004-04-28 Syngenta Participations Ag Avermectins substituted in the 4-position having pesticidal properties
AR036486A1 (es) * 2001-08-28 2004-09-15 Syngenta Participations Ag Derivados 4"-desoxi-4"-(s)-amino avermectina, composicion plaguicida, procedimiento para la preparacion de esa composicion, metodo para controlar plagas, y uso de estos derivados para preparar una composicion
TW200407330A (en) * 2002-05-07 2004-05-16 Syngenta Participations Ag 4"-Deoxy-4"-(S)-amido avermectin derivatives
GB0302310D0 (en) 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0302309D0 (en) * 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin monosaccharide derivatives substituted in the 4 -position having pesticidal properties
GB0302308D0 (en) * 2003-01-31 2003-03-05 Syngenta Participations Ag Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302548D0 (en) * 2003-02-04 2003-03-12 Syngenta Participations Ag Avermectins substituted in the 4"- and 4' -positions having pesticidal properties
GB0320176D0 (en) * 2003-08-28 2003-10-01 Syngenta Participations Ag Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
EP1632498A1 (de) * 2004-09-03 2006-03-08 Syngenta Participations AG Derivate von Avermectin, Avermectin Monosaccharid und Avermectin Aglycon
DE102007007750A1 (de) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Avermectinderivate
NZ593184A (en) 2008-12-04 2012-11-30 Merial Ltd Dimeric avermectin and milbemycin derivatives
AU2010330844B2 (en) 2009-12-17 2014-11-27 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
MX358476B (es) 2011-12-02 2018-08-22 Merial Ltd Formulaciones de moxidectina inyectables de larga acción y formas de cristal de moxidectina novedosas.
CN103396465B (zh) * 2013-07-19 2016-01-20 中国农业科学院植物保护研究所 一种阿维菌素烟碱二效价化合物及其制备和应用
CN113150053A (zh) * 2020-01-22 2021-07-23 华东理工大学 偶氮苯类阿维菌素衍生物及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
IN167980B (de) * 1987-01-23 1991-01-19 Pfizer
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
US4873224A (en) * 1988-05-23 1989-10-10 Merck & Co., Inc. Avermectin derivatives

Also Published As

Publication number Publication date
JPH03141291A (ja) 1991-06-17
AU630992B2 (en) 1992-11-12
DE69032797T2 (de) 1999-07-01
AU5998890A (en) 1991-01-31
IE902752A1 (en) 1991-02-27
JPH0826059B2 (ja) 1996-03-13
EP0411897B1 (de) 1998-12-02
CA2022113A1 (en) 1991-02-01
NZ234685A (en) 1992-11-25
EP0411897A3 (en) 1991-10-16
US5023241A (en) 1991-06-11
ATE174033T1 (de) 1998-12-15
ZA905996B (en) 1991-05-29
EP0411897A2 (de) 1991-02-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee