DE69032370T2 - Regioselektive substitutionen von cyclodextrinen - Google Patents

Regioselektive substitutionen von cyclodextrinen

Info

Publication number
DE69032370T2
DE69032370T2 DE69032370T DE69032370T DE69032370T2 DE 69032370 T2 DE69032370 T2 DE 69032370T2 DE 69032370 T DE69032370 T DE 69032370T DE 69032370 T DE69032370 T DE 69032370T DE 69032370 T2 DE69032370 T2 DE 69032370T2
Authority
DE
Germany
Prior art keywords
hydroxyls
cyclodextrines
substitution
cyclodextrins
regioselective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69032370T
Other languages
English (en)
Other versions
DE69032370D1 (de
Inventor
Bengt Lindberg
Josef Pitha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23298989&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69032370(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE69032370D1 publication Critical patent/DE69032370D1/de
Publication of DE69032370T2 publication Critical patent/DE69032370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69032370T 1989-04-03 1990-03-30 Regioselektive substitutionen von cyclodextrinen Expired - Lifetime DE69032370T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33260689A 1989-04-03 1989-04-03
PCT/EP1990/000524 WO1990012035A1 (en) 1989-04-03 1990-03-30 Regioselective substitutions in cyclodextrins

Publications (2)

Publication Number Publication Date
DE69032370D1 DE69032370D1 (de) 1998-07-09
DE69032370T2 true DE69032370T2 (de) 1998-10-29

Family

ID=23298989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69032370T Expired - Lifetime DE69032370T2 (de) 1989-04-03 1990-03-30 Regioselektive substitutionen von cyclodextrinen

Country Status (14)

Country Link
EP (1) EP0465535B1 (de)
JP (1) JP2792610B2 (de)
KR (1) KR0163440B1 (de)
AT (1) ATE166884T1 (de)
AU (1) AU631628B2 (de)
CA (1) CA2047726C (de)
DE (1) DE69032370T2 (de)
DK (1) DK0465535T3 (de)
ES (1) ES2116982T3 (de)
FI (1) FI101385B (de)
HK (1) HK1009335A1 (de)
HU (1) HUT58770A (de)
NO (1) NO304269B1 (de)
WO (1) WO1990012035A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4401618A1 (de) * 1994-01-20 1995-07-27 Consortium Elektrochem Ind Verfahren zur Herstellung von aminofunktionellen Cyclodextrin Derivaten
DE19505263A1 (de) * 1995-02-16 1996-08-22 Consortium Elektrochem Ind Verfahren zur Reinigung von wasserlöslichen Cyclodextrinderivaten
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
US6197294B1 (en) 1998-10-26 2001-03-06 Neurotech S.A. Cell surface molecule-induced macrophage activation
TWI242015B (en) 1999-11-29 2005-10-21 Akzo Nobel Nv 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
EP2272503B1 (de) 2003-03-28 2013-03-20 Ares Trading S.A. Orale Zubereitungen enthaltend Cladribin
JP5256611B2 (ja) 2003-03-28 2013-08-07 アレス トレーディング ソシエテ アノニム クラドリビンの経口製剤
MXPA05010330A (es) 2003-03-28 2006-05-31 Ivax Corp Formulaciones de cladribina para el mejor suministro oral y a traves de la mucosa.
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
ES2774901T3 (es) * 2012-02-15 2020-07-23 Cydex Pharmaceuticals Inc Proceso para la fabricación de derivados de ciclodextrina
KR20200106100A (ko) 2012-02-28 2020-09-10 사이덱스 파마슈티칼스, 인크. 알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법
JP6557144B2 (ja) 2012-10-22 2019-08-07 サイデックス・ファーマシューティカルズ・インコーポレイテッド アルキル化シクロデキストリン組成物ならびにその調製方法および使用方法
HUE063851T2 (hu) 2014-08-22 2024-02-28 Cydex Pharmaceuticals Inc Frakcionált alkilezett ciklodextrin készítmények és eljárás ezek elõállítására és alkalmazására
JP2019163344A (ja) * 2016-07-25 2019-09-26 国立大学法人 東京大学 擬ポリロタキサン、ポリロタキサン、及びそれらの製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
DE2260785A1 (de) * 1972-12-12 1974-06-20 Morishita Pharma Verfahren zur herstellung von hydroxyaethylstaerke, die in der 6-stellung des glucoserings durch viele hydroxyaethylgruppen substituiert ist
EP0146841A3 (de) * 1983-12-17 1986-11-20 Consortium für elektrochemische Industrie GmbH Wasserlösliche Mischether des beta-Cyclodextrins und ein Verfahren zu ihrer Herstellung
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
AU7453191A (en) * 1990-03-02 1991-09-18 Australian Commercial Research & Development Limited Cyclodextrin compositions and methods for pharmaceutical and industrial applications

Also Published As

Publication number Publication date
DK0465535T3 (da) 1999-03-01
KR0163440B1 (ko) 1998-11-16
EP0465535B1 (de) 1998-06-03
WO1990012035A1 (en) 1990-10-18
CA2047726A1 (en) 1990-10-04
ATE166884T1 (de) 1998-06-15
CA2047726C (en) 2001-04-17
FI914620A0 (fi) 1991-10-02
NO913871L (no) 1991-10-02
AU5358790A (en) 1990-11-05
HUT58770A (en) 1992-03-30
ES2116982T3 (es) 1998-08-01
KR920701258A (ko) 1992-08-11
JPH04504275A (ja) 1992-07-30
AU631628B2 (en) 1992-12-03
EP0465535A1 (de) 1992-01-15
HU902934D0 (en) 1991-12-30
FI101385B1 (fi) 1998-06-15
FI101385B (fi) 1998-06-15
NO913871D0 (no) 1991-10-02
JP2792610B2 (ja) 1998-09-03
NO304269B1 (no) 1998-11-23
HK1009335A1 (en) 1999-05-28
DE69032370D1 (de) 1998-07-09

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Legal Events

Date Code Title Description
8363 Opposition against the patent