DE69031472D1 - Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke mit einem Rotor - Google Patents

Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke mit einem Rotor

Info

Publication number
DE69031472D1
DE69031472D1 DE69031472T DE69031472T DE69031472D1 DE 69031472 D1 DE69031472 D1 DE 69031472D1 DE 69031472 T DE69031472 T DE 69031472T DE 69031472 T DE69031472 T DE 69031472T DE 69031472 D1 DE69031472 D1 DE 69031472D1
Authority
DE
Germany
Prior art keywords
chamber
chambers
rotor
shuttle
rotor body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69031472T
Other languages
English (en)
Other versions
DE69031472T2 (de
Inventor
Carl A Burtis
Wayne F Johnson
William A Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lockheed Martin Energy Systems Inc
Original Assignee
Lockheed Martin Energy Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lockheed Martin Energy Systems Inc filed Critical Lockheed Martin Energy Systems Inc
Publication of DE69031472D1 publication Critical patent/DE69031472D1/de
Application granted granted Critical
Publication of DE69031472T2 publication Critical patent/DE69031472T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/07—Centrifugal type cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/065—Valves, specific forms thereof with moving parts sliding valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/111666—Utilizing a centrifuge or compartmented rotor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69031472T 1989-05-30 1990-05-09 Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke mit einem Rotor Expired - Fee Related DE69031472T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/359,007 US5173262A (en) 1987-07-17 1989-05-30 Rotor assembly and method for automatically processing liquids

Publications (2)

Publication Number Publication Date
DE69031472D1 true DE69031472D1 (de) 1997-10-23
DE69031472T2 DE69031472T2 (de) 1998-02-05

Family

ID=23411941

Family Applications (5)

Application Number Title Priority Date Filing Date
DE69031473T Expired - Fee Related DE69031473T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke
DE69031169T Expired - Lifetime DE69031169D1 (de) 1989-05-30 1990-05-09 Rotor und verfahren zur automatischen verarbeitung von flüssigkeiten für labor- und bioanalytische zwecke
DE69031472T Expired - Fee Related DE69031472T2 (de) 1989-05-30 1990-05-09 Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke mit einem Rotor
DE69031474T Expired - Fee Related DE69031474T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke
DE69031470T Expired - Fee Related DE69031470T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69031473T Expired - Fee Related DE69031473T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke
DE69031169T Expired - Lifetime DE69031169D1 (de) 1989-05-30 1990-05-09 Rotor und verfahren zur automatischen verarbeitung von flüssigkeiten für labor- und bioanalytische zwecke

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE69031474T Expired - Fee Related DE69031474T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke
DE69031470T Expired - Fee Related DE69031470T2 (de) 1989-05-30 1990-05-09 Rotor und Verfahren zur automatischen Verarbeitung von Flüssigkeiten für labor- und bioanalytische Zwecke

Country Status (7)

Country Link
US (1) US5173262A (de)
EP (5) EP0631126B1 (de)
JP (1) JPH07111436B2 (de)
AT (5) ATE158406T1 (de)
CA (1) CA2053894A1 (de)
DE (5) DE69031473T2 (de)
WO (1) WO1990015321A2 (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
US6235531B1 (en) 1993-09-01 2001-05-22 Abaxis, Inc. Modified siphons for improved metering precision
US5565105A (en) * 1993-09-30 1996-10-15 The Johns Hopkins University Magnetocentrifugation
US5960344A (en) * 1993-12-20 1999-09-28 Norand Corporation Local area network having multiple channel wireless access
US5627041A (en) * 1994-09-02 1997-05-06 Biometric Imaging, Inc. Disposable cartridge for an assay of a biological sample
US6327031B1 (en) * 1998-09-18 2001-12-04 Burstein Technologies, Inc. Apparatus and semi-reflective optical system for carrying out analysis of samples
US6143247A (en) * 1996-12-20 2000-11-07 Gamera Bioscience Inc. Affinity binding-based system for detecting particulates in a fluid
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US6709869B2 (en) 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5783446A (en) * 1996-03-04 1998-07-21 Biocircuits Corporation Particle assay using fluid velocity gradients
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
AU4428497A (en) * 1996-09-20 1998-04-14 James P. Demers Spatially addressable combinatorial chemical arrays in cd-rom format
US5789259A (en) * 1996-09-27 1998-08-04 Robert A. Levine Method and apparatus for mixing samples in a capillary tube
HUP0003152A3 (en) * 1997-02-28 2002-09-30 Burstein Lab Inc Irvine Laboratory in a disk
US6632399B1 (en) * 1998-05-22 2003-10-14 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays
US6063589A (en) 1997-05-23 2000-05-16 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement on a microfluidics system
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
CA2301095A1 (en) 1997-08-15 1999-02-25 Alexion Pharmaceuticals, Inc. Apparatus for performing assays at reaction sites
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
ATE272213T1 (de) * 1999-06-18 2004-08-15 Gamera Bioscience Corp Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests
WO2000078464A1 (fr) * 1999-06-23 2000-12-28 Hitachi, Ltd. Separateur centrifuge et dispositif de preparation d'echantillons mettant en oeuvre ce separateur
JP2003533682A (ja) * 2000-05-15 2003-11-11 テカン・トレーディング・アクチェンゲゼルシャフト 双方向流動遠心ミクロ流体装置
AU7024801A (en) * 2000-06-28 2002-01-08 3M Innovative Properties Co Enhanced sample processing devices, systems and methods
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US7061594B2 (en) * 2000-11-09 2006-06-13 Burstein Technologies, Inc. Disc drive system and methods for use with bio-discs
GB0027516D0 (en) * 2000-11-10 2000-12-27 Amersham Pharm Biotech Uk Ltd Support and method for cell based assays
US7087203B2 (en) * 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US7026131B2 (en) * 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US20020076354A1 (en) * 2000-12-01 2002-06-20 Cohen David Samuel Apparatus and methods for separating components of particulate suspension
US7200088B2 (en) * 2001-01-11 2007-04-03 Burstein Technologies, Inc. System and method of detecting investigational features related to a sample
WO2003087827A2 (en) 2001-04-11 2003-10-23 Burstein Technologies, Inc. Multi-parameter assays including analysis discs and methods relating thereto
US7221632B2 (en) * 2001-07-12 2007-05-22 Burstein Technologies, Inc. Optical disc system and related detecting methods for analysis of microscopic structures
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
US20030064872A1 (en) * 2001-07-20 2003-04-03 Worthington Mark Oscar Optical analysis disc and related drive assembly for performing interactive centrifugation
US20040226348A1 (en) * 2001-07-24 2004-11-18 Phillip Bruce Magnetic assisted detection of magnetic beads using optical disc drives
US20030230383A1 (en) * 2001-07-24 2003-12-18 Glenn Sasaki Method and apparatus for bonded fluidic circuit for optical bio-disc
US20030129665A1 (en) * 2001-08-30 2003-07-10 Selvan Gowri Pyapali Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems
US20080094974A1 (en) * 2001-11-09 2008-04-24 Burstein Technologies, Inc. Optical disc system and related detecting methods for analysis of microscopic structures
AU2002352735A1 (en) * 2001-11-20 2003-06-10 Burstein Technologies, Inc. Optical bio-discs and microfluidic devices for analysis of cells
AU2003202951A1 (en) * 2002-01-14 2003-07-30 Burstein Technologies, Inc. Method and apparatus for visualizing data
CA2471018A1 (en) * 2002-01-28 2003-08-07 Burstein Technologies, Inc. Methods and apparatus for logical triggering of an optical bio-disc
US20050002827A1 (en) * 2002-01-29 2005-01-06 Mcintyre Kevin Robert Optical discs including equi-radial and/or spiral analysis zones and related disc drive systems and methods
US20040241381A1 (en) * 2002-01-31 2004-12-02 Chen Yihfar Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs
US20050023765A1 (en) * 2002-01-31 2005-02-03 Coombs James Howard Bio-safety features for optical analysis disc and disc system including same
WO2003064996A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safe dispenser and optical analysis disc assembly
WO2003065354A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Manufacturing processes for making optical analysis discs including successive patterning operations and optical discs thereby manufactured
US7214348B2 (en) * 2002-07-26 2007-05-08 Applera Corporation Microfluidic size-exclusion devices, systems, and methods
WO2004095034A1 (en) * 2003-04-23 2004-11-04 Nagaoka & Co., Ltd. Optical bio-discs including spiral fluidic circuits for performing assays
WO2004113871A2 (en) * 2003-06-19 2004-12-29 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
WO2005001429A2 (en) * 2003-06-27 2005-01-06 Nagaoka & Co., Ltd. Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays
US20070274863A1 (en) * 2003-07-25 2007-11-29 Horacio Kido Fluidic circuits for sample preparation including bio-discs and methods relating thereto
WO2006077695A1 (ja) * 2005-01-24 2006-07-27 Matsushita Electric Industrial Co., Ltd. 送液装置及び送液方法
US20060263265A1 (en) * 2005-05-23 2006-11-23 Der-Ren Kang Blood micro-separator
JP4619224B2 (ja) * 2005-07-27 2011-01-26 パナソニック株式会社 回転分析デバイス
JP4702182B2 (ja) * 2006-05-25 2011-06-15 パナソニック株式会社 光学分析用デバイス及び光学分析装置
EP1939629A3 (de) * 2006-08-11 2011-03-09 Samsung Electronics Co., Ltd. Vorrichtung zur zentrifugalkraftbasierten Magnetpositionssteuerung sowie scheibenförmiges Mikrofluidiksystem
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
ES2753136T3 (es) * 2006-12-22 2020-04-07 Diasorin S P A Métodos de transferencia térmica para sistemas microfluídicos
KR20090105934A (ko) * 2006-12-22 2009-10-07 쓰리엠 이노베이티브 프로퍼티즈 컴파니 향상된 샘플 처리 장치, 시스템 및 방법
JP4614992B2 (ja) * 2007-07-27 2011-01-19 パナソニック株式会社 分析用デバイスとこれを使用する分析装置および分析方法
JP4586054B2 (ja) * 2007-08-31 2010-11-24 株式会社日立ハイテクノロジーズ 自動分析装置
CN101918528B (zh) * 2007-12-10 2013-07-17 三星电子株式会社 薄膜生物阀装置和其控制设备
KR101390717B1 (ko) * 2008-09-02 2014-04-30 삼성전자주식회사 미세유동장치 및 미세유동장치에의 시료주입방법
EP2309266A1 (de) * 2009-09-21 2011-04-13 F. Hoffmann-La Roche AG Verfahren zur Durchführung von Reaktionen in einer Analysevorrichtung
US8821810B2 (en) * 2010-02-03 2014-09-02 President And Fellows Of Harvard College Devices and methods for multiplexed assays
GB2479139A (en) * 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
KR20120091631A (ko) * 2011-02-09 2012-08-20 삼성전자주식회사 미세유동장치
KR20120093636A (ko) 2011-02-15 2012-08-23 삼성전자주식회사 미세유동장치
KR101149357B1 (ko) * 2011-11-14 2012-05-30 바디텍메드 주식회사 반사식 흡광도 측정 장치 및 이를 포함하는 반사식 흡광도 및 측방유동 분석 일체형 장치
KR20130086743A (ko) * 2012-01-26 2013-08-05 삼성전자주식회사 미세유동장치 및 그 제어방법
EP2634579B1 (de) * 2012-03-03 2014-12-17 Astrium GmbH Verfahren zur Durchführung von Immuno-Assays in Schwerelosigkeit
DE102012205511A1 (de) * 2012-04-04 2013-10-10 Robert Bosch Gmbh Revolverbauteil für ein Reagenzgefäß
TWI513510B (zh) * 2012-08-09 2015-12-21 Nat Univ Tsing Hua 離心式粒子分離暨檢測裝置
DE102012107651A1 (de) * 2012-08-21 2014-02-27 Astrium Gmbh Verfahren zur Durchführung einer biochemischen Analyse, insbesondere im Weltraum
EP2917362A4 (de) * 2012-11-07 2016-07-13 Sandstone Diagnostics Inc Verfahren und vorrichtungen zur verarbeitung von proben und zur zählung von zellen
JP6527531B2 (ja) 2014-06-06 2019-06-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 生体試料を分析するための計量チャンバを備える回転可能なカートリッジ
EP2952258A1 (de) * 2014-06-06 2015-12-09 Roche Diagnostics GmbH Drehbare Kartusche zur Analyse einer biologischen Probe
EP2952257A1 (de) 2014-06-06 2015-12-09 Roche Diagnostics GmbH Drehbare Patrone zur Verarbeitung und Analyse einer biologischen Probe
EP2957890A1 (de) * 2014-06-16 2015-12-23 Roche Diagnostics GmbH Patrone mit drehbarem Deckel
WO2016002728A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび磁性粒子を含む液体から液体を取り除く方法
US10309976B2 (en) 2014-06-30 2019-06-04 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
CN106662596A (zh) * 2014-06-30 2017-05-10 松下健康医疗控股株式会社 试样分析用基板和试样分析装置
CN107209193B (zh) 2014-12-12 2019-08-02 普和希控股公司 试样分析用基板、试样分析装置、试样分析系统以及试样分析系统用程序
US9909975B1 (en) * 2016-10-07 2018-03-06 Biosurfit, S.A. Device for rotation about an axis of rotation to drive liquid flow within the device comprising a first element, a second element and the radially outer wall of a cavity define a detection chamber
CN111530640B (zh) * 2020-04-29 2021-09-21 济南格利特科技有限公司 一种能够调节离心力的血液处理装置

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3586484A (en) * 1969-05-23 1971-06-22 Atomic Energy Commission Multistation analytical photometer and method of use
BE792465A (fr) * 1971-12-09 1973-03-30 Atomic Energy Commission Rotor perfectionne pour analyseur photometrique rotatif convenant en particulier dans des conditions d'apesanteur
US3873217A (en) * 1973-07-24 1975-03-25 Atomic Energy Commission Simplified rotor for fast analyzer of rotary cuvette type
US3899296A (en) * 1974-07-17 1975-08-12 Us Energy Whole blood analysis rotor for a multistation dynamic photometer
US4035156A (en) * 1977-01-21 1977-07-12 The United States Of America As Represented By The United States Energy Research And Development Administration Filter type rotor for multistation photometer
IN154925B (de) * 1979-10-26 1984-12-22 Guigan Jean
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
CA1152353A (en) * 1980-05-05 1983-08-23 Georges Revillet Multicuvette rotor for analyser
DE3044385A1 (de) * 1980-11-25 1982-06-24 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes rotoreinsatzelement
FR2503866A1 (fr) * 1981-04-14 1982-10-15 Guigan Jean Dispositif pour delivrer une dose determinee d'un echantillon de liquide dans une cellule et procede associe
DE3134611A1 (de) * 1981-09-01 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes mittel
DE3134560A1 (de) * 1981-09-01 1983-03-17 Boehringer Mannheim Gmbh, 6800 Mannheim Vorrichtung und verfahren zum steuern und mischen einer der zentrifugalkraft ausgesetzten fluessigkeitsstroemung
NZ201901A (en) * 1981-09-25 1986-11-12 Commw Serum Lab Commission An apparatus suitable for performing automated heterogeneous immunoassays in a plurality of samples
DE3425008A1 (de) * 1984-07-06 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und vorrichtung zur durchfuehrung analytischer bestimmungen
US4883763A (en) * 1984-05-03 1989-11-28 Abbott Laboratories Sample processor card for centrifuge
DE3425009A1 (de) * 1984-07-06 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim Vorrichtung zum durchspuelen einer in einem feld befindlichen substanz mit einem fluessigen spuelmittel in mehreren spuelvorgaengen und zur ueberfuehrung des beim letzten spuelvorgang aus dem feld austretenden spuelmittels in eine kuevette
FR2572533B1 (fr) * 1984-10-26 1986-12-26 Guigan Jean Procede destine a realiser l'analyse medicale d'un echantillon liquide a l'aide d'au moins un reactif liquide et dispositif pour la mise en oeuvre du procede
FR2575181B1 (fr) * 1984-12-21 1987-01-16 Guigan Jean Procede pour la realisation d'analyses medicales, barrette de conditionnement et dispositif pour la mise en oeuvre du procede
FR2575293B1 (fr) * 1984-12-21 1987-03-20 Inovelf Sa Rotor a pipetage dynamique pour dispositif d'analyse a centrifugation
US4740472A (en) * 1985-08-05 1988-04-26 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer
US4774057A (en) * 1985-10-25 1988-09-27 Technicon Instruments Corporation Dual liquid dispenser package
FR2592170B1 (fr) * 1985-12-20 1988-02-05 Guigan Jean Procede et dispositif pour delivrer une quantite predeterminee de plasma a partir d'un echantillon de sang en vue d'analyses.
US4847205A (en) * 1987-04-08 1989-07-11 Martin Marietta Energy Systems, Inc. Device and method for automated separation of a sample of whole blood into aliquots
US4892708A (en) * 1987-07-01 1990-01-09 Miles Inc. Fluid separation and processing device
US4835106A (en) * 1987-07-17 1989-05-30 Martin Marietta Energy Systems, Inc. Rotor for processing liquids using movable capillary tubes
US4999304A (en) * 1987-12-28 1991-03-12 Miles Inc. Dynamic braking centrifuge

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ATE158408T1 (de) 1997-10-15
WO1990015321A2 (en) 1990-12-13
DE69031470D1 (de) 1997-10-23
DE69031474D1 (de) 1997-10-23
EP0631124B1 (de) 1997-09-17
DE69031474T2 (de) 1998-01-29
DE69031169D1 (de) 1997-09-04
DE69031470T2 (de) 1998-01-29
EP0631125A1 (de) 1994-12-28
EP0477206A1 (de) 1992-04-01
ATE158406T1 (de) 1997-10-15
DE69031472T2 (de) 1998-02-05
JPH07111436B2 (ja) 1995-11-29
ATE158405T1 (de) 1997-10-15
EP0477206B1 (de) 1997-07-30
CA2053894A1 (en) 1990-12-01
ATE156266T1 (de) 1997-08-15
EP0629850A3 (en) 1994-12-28
EP0629850B1 (de) 1997-09-17
US5173262A (en) 1992-12-22
EP0631126A1 (de) 1994-12-28
EP0629850A2 (de) 1994-12-21
ATE158407T1 (de) 1997-10-15
EP0631125B1 (de) 1997-09-17
DE69031473T2 (de) 1998-01-29
WO1990015321A3 (en) 2004-04-29
DE69031473D1 (de) 1997-10-23
EP0631126B1 (de) 1997-09-17
EP0631124A1 (de) 1994-12-28
JPH04507288A (ja) 1992-12-17

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