DE69029291T2 - Verwendung von Lithiumsalzen zur Lysis von Erythrozyten und zur Denaturierung von Hämoglobin - Google Patents

Verwendung von Lithiumsalzen zur Lysis von Erythrozyten und zur Denaturierung von Hämoglobin

Info

Publication number
DE69029291T2
DE69029291T2 DE69029291T DE69029291T DE69029291T2 DE 69029291 T2 DE69029291 T2 DE 69029291T2 DE 69029291 T DE69029291 T DE 69029291T DE 69029291 T DE69029291 T DE 69029291T DE 69029291 T2 DE69029291 T2 DE 69029291T2
Authority
DE
Germany
Prior art keywords
hemoglobin
denaturation
lysis
erythrocytes
lithium salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029291T
Other languages
English (en)
Other versions
DE69029291D1 (de
Inventor
Lynette Lewis
Teresa M Yip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69029291D1 publication Critical patent/DE69029291D1/de
Publication of DE69029291T2 publication Critical patent/DE69029291T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DE69029291T 1989-07-13 1990-07-03 Verwendung von Lithiumsalzen zur Lysis von Erythrozyten und zur Denaturierung von Hämoglobin Expired - Lifetime DE69029291T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37958289A 1989-07-13 1989-07-13

Publications (2)

Publication Number Publication Date
DE69029291D1 DE69029291D1 (de) 1997-01-16
DE69029291T2 true DE69029291T2 (de) 1997-04-03

Family

ID=23497825

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029291T Expired - Lifetime DE69029291T2 (de) 1989-07-13 1990-07-03 Verwendung von Lithiumsalzen zur Lysis von Erythrozyten und zur Denaturierung von Hämoglobin

Country Status (12)

Country Link
EP (1) EP0407860B1 (de)
JP (1) JP2843919B2 (de)
AT (1) ATE145991T1 (de)
AU (1) AU625137B2 (de)
DE (1) DE69029291T2 (de)
DK (1) DK0407860T3 (de)
ES (1) ES2095224T3 (de)
FI (1) FI102698B (de)
GR (1) GR3022522T3 (de)
HU (1) HU206157B (de)
IE (1) IE902549A1 (de)
IL (1) IL94724A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151369A (en) * 1989-07-13 1992-09-29 Miles Inc. Lithium salts as red blood cell lysing and hemoglobin denaturing reagents
US5236664A (en) * 1991-04-08 1993-08-17 University Of South Alabama Apparatus for monitoring blood loss
DE4206932A1 (de) * 1992-03-05 1993-09-09 Boehringer Mannheim Gmbh Immunologische methode zur bestimmung eines haemoglobinderivates
US5610076A (en) * 1994-04-29 1997-03-11 Alteon Inc. Method for detecting hemoglobin advanced glycosylation endproducts
US6174734B1 (en) 1997-10-24 2001-01-16 Abbott Laboratories Measurement of glycated hemoglobin
JPWO2003083479A1 (ja) * 2002-03-29 2005-08-04 松下電器産業株式会社 血液処理方法、血液処理デバイス、ヘモグロビン類測定方法およびヘモグロビン類測定デバイス
CA2604474C (en) 2005-04-14 2012-07-17 Hirotaka Tanaka Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method
EP3447494B1 (de) 2007-10-04 2020-07-15 PHC Holdings Corporation Analyseverfahren mit einer analysevorrichtung
US8574913B2 (en) 2007-10-30 2013-11-05 Panasonic Corporation Method for measurement of hemoglobin and hemoglobin derivative, and measurement kit
CN102246036B (zh) 2008-12-11 2016-01-20 积水医疗株式会社 含有糖化血红蛋白的试样的前处理方法
WO2020163211A1 (en) * 2019-02-06 2020-08-13 Siemens Healthcare Diagnostics Inc. Methods of blood sample suspension

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto
US4970171A (en) * 1987-11-09 1990-11-13 Miles Inc. Denaturant reagents for convenient determination of hemoglobin derivatives in blood

Also Published As

Publication number Publication date
ES2095224T3 (es) 1997-02-16
FI903510A0 (fi) 1990-07-11
EP0407860A2 (de) 1991-01-16
JPH0351759A (ja) 1991-03-06
ATE145991T1 (de) 1996-12-15
IL94724A0 (en) 1991-04-15
GR3022522T3 (en) 1997-05-31
FI102698B1 (fi) 1999-01-29
EP0407860B1 (de) 1996-12-04
EP0407860A3 (en) 1992-03-04
AU625137B2 (en) 1992-07-02
DE69029291D1 (de) 1997-01-16
IE902549A1 (en) 1991-02-27
FI102698B (fi) 1999-01-29
JP2843919B2 (ja) 1999-01-06
IL94724A (en) 1994-02-27
AU5890990A (en) 1991-01-17
HU904183D0 (en) 1990-12-28
DK0407860T3 (da) 1997-05-12
HUT57902A (en) 1991-12-30
HU206157B (en) 1992-08-28

Similar Documents

Publication Publication Date Title
DK622788A (da) Analysemetode og testsystem til bestemmelse af den relative maengde af et bestemt haemoglobinderivat i en blodproeve
IL103056A (en) Method for sphering of red blood cells
DE69906859T2 (de) Neue Reagenzien und Methoden zur Lyse von Erythrozyten
WO1996042015A3 (en) Reagent and method for differential determination of leukocytes in blood
ATE93323T1 (de) Latex-agglutinations-immuntest in gegenwart von haemoglobin.
ATE145991T1 (de) Verwendung von lithiumsalzen zur lysis von erythrozyten und zur denaturierung von hämoglobin
PT95928A (pt) Processo para a preparacao de um regente utilizado na determinacao automatica, em citometria de fluxo, de, pelo menos, uma subpopulacao leucocitaria a partir de sangue total
DE59310046D1 (de) Immunologische Methode zur Bestimmung von HbAIc
WO1996042015B1 (en) Reagent and method for differential determination of leukocytes in blood
CA2019426A1 (en) Lithium salts as red blood cells lysing hemoglobin denaturing reagents
EP0154522A2 (de) Verfahren zur Herstellung von kugelförmigen Vollblut-Erythrocyten und Fixierung derselben
SE8002591L (sv) "heme-koncentrat"
DK56386D0 (da) Reagens til ved haemagglunitation at bestemme antistoffer mod bakterielle toksiner, fremgangsmaade til fremstilling af reagenset og dettes anvendelse
DK0625707T3 (da) Fremgangsmåde og præparat til lyse af erytrocytter, blodpræparat og fremgangsmåde til leukocytanalyse
SPECTOR et al. A Serum Protein Electrophoretic Abnormality Following Experimental Burn Trauma
Giri et al. Agar Electrophoresis Part III-ANIMAL HEMOGLOBIN
FR2391472A1 (fr) Agent pour la determination de phenomenes infectieux et immunologiques
NL7704891A (en) Immunological haemolysis determn. of infections and immune processes - by selective haemolysis of damaged erythrocytes

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US

8328 Change in the person/name/address of the agent

Representative=s name: MAIER, D., DIPL.-ING. UNIV., PAT.-ASS., 81739 MUEN