DE69028774T2 - Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins - Google Patents

Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins

Info

Publication number
DE69028774T2
DE69028774T2 DE69028774T DE69028774T DE69028774T2 DE 69028774 T2 DE69028774 T2 DE 69028774T2 DE 69028774 T DE69028774 T DE 69028774T DE 69028774 T DE69028774 T DE 69028774T DE 69028774 T2 DE69028774 T2 DE 69028774T2
Authority
DE
Germany
Prior art keywords
alkylthiopyrimidine
difluoromethoxy
bis
base
monochlorodifluoromethane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69028774T
Other languages
English (en)
Other versions
DE69028774D1 (de
Inventor
Sumio Yoshino
Kazuyuki Watanabe
Mikio Akazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Kawaguchi Chemical Industry Co Ltd
AGC Inc
Original Assignee
Ciba Geigy AG
Asahi Glass Co Ltd
Kawaguchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Asahi Glass Co Ltd, Kawaguchi Chemical Industry Co Ltd filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE69028774D1 publication Critical patent/DE69028774D1/de
Publication of DE69028774T2 publication Critical patent/DE69028774T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
DE69028774T 1989-01-24 1990-07-24 Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins Expired - Lifetime DE69028774T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1013307A JPH0662588B2 (ja) 1989-01-24 1989-01-24 ４，６―ビス（ジフルオロメトキシ）―２―メチルチオピリミジンの製造法
EP90114191A EP0468069B1 (de) 1989-01-24 1990-07-24 Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins

Publications (2)

Publication Number Publication Date
DE69028774D1 DE69028774D1 (de) 1996-11-07
DE69028774T2 true DE69028774T2 (de) 1997-02-13

Family

ID=40139217

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69028774T Expired - Lifetime DE69028774T2 (de) 1989-01-24 1990-07-24 Verfahren zur Herstellung eines 4,6-Bis(difluormethoxy)-2-alkylthiopyrimidins

Country Status (6)

Country Link
US (1) US5071982A (de)
EP (1) EP0468069B1 (de)
JP (1) JPH0662588B2 (de)
AT (1) ATE143660T1 (de)
DE (1) DE69028774T2 (de)
ES (1) ES2094130T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2208734C (en) * 1996-07-24 2006-05-30 Lonza Ag Process for preparing 4,6-bis(difluoro-methoxy)pyrimidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542216A (en) * 1984-03-27 1985-09-17 Ciba Geigy Corporation Process for producing fluoroalkoxyaminopyrimidines
US4692524A (en) * 1986-05-02 1987-09-08 Ciba-Geigy Corporation Process for the preparation of pyrimidine derivatives
US4900827A (en) * 1988-12-22 1990-02-13 Ciba-Geigy Corporation Process for the preparation of pyrimidine derivatives

Also Published As

Publication number Publication date
JPH0662588B2 (ja) 1994-08-17
US5071982A (en) 1991-12-10
ATE143660T1 (de) 1996-10-15
EP0468069A1 (de) 1992-01-29
JPH02196773A (ja) 1990-08-03
EP0468069B1 (de) 1996-10-02
ES2094130T3 (es) 1997-01-16
DE69028774D1 (de) 1996-11-07

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Legal Events

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