DE69024038D1 - Kerne für technetium-radioarzneimittel. - Google Patents

Kerne für technetium-radioarzneimittel.

Info

Publication number
DE69024038D1
DE69024038D1 DE69024038T DE69024038T DE69024038D1 DE 69024038 D1 DE69024038 D1 DE 69024038D1 DE 69024038 T DE69024038 T DE 69024038T DE 69024038 T DE69024038 T DE 69024038T DE 69024038 D1 DE69024038 D1 DE 69024038D1
Authority
DE
Germany
Prior art keywords
technetium
substituted
radio
core
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69024038T
Other languages
English (en)
Other versions
DE69024038T2 (de
Inventor
Colin Mill Archer
Jonathan Robin Dilworth
Panna Jobanputra
Ian Andrew Latham
Russell Martin Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10662202&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69024038(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham International PLC filed Critical Amersham International PLC
Publication of DE69024038D1 publication Critical patent/DE69024038D1/de
Application granted granted Critical
Publication of DE69024038T2 publication Critical patent/DE69024038T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69024038T 1989-08-29 1990-08-28 Kerne für technetium-radioarzneimittel. Revoked DE69024038T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898919488A GB8919488D0 (en) 1989-08-29 1989-08-29 New cores for technetium radiopharmaceuticals
PCT/GB1990/001330 WO1991003262A1 (en) 1989-08-29 1990-08-28 New cores for technetium radiopharmaceuticals

Publications (2)

Publication Number Publication Date
DE69024038D1 true DE69024038D1 (de) 1996-01-18
DE69024038T2 DE69024038T2 (de) 1996-04-25

Family

ID=10662202

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024038T Revoked DE69024038T2 (de) 1989-08-29 1990-08-28 Kerne für technetium-radioarzneimittel.

Country Status (7)

Country Link
EP (1) EP0441953B1 (de)
JP (2) JP3221875B2 (de)
AT (1) ATE131072T1 (de)
CA (1) CA2039732A1 (de)
DE (1) DE69024038T2 (de)
GB (1) GB8919488D0 (de)
WO (1) WO1991003262A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601800A (en) * 1991-11-08 1997-02-11 Curators Of The University Of Missouri New multifunctional ligands for potential use in the design therapeutic or diagnostic radiopharmaceutical imaging agents
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5541289A (en) * 1994-03-30 1996-07-30 Washington University Phosphine containing amino acids and peptides and methods of preparing and using same
IT1286879B1 (it) * 1996-11-21 1998-07-17 Consiglio Nazionale Ricerche Leganti 1,3-difosfinopropanici e complessi da essi formati con metalli di transizione,loro preparazione e uso
US6403054B1 (en) 1997-05-28 2002-06-11 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US6251364B1 (en) 1999-03-29 2001-06-26 Dupont Pharmaceuticals Company Ternary ligand complexes useful as radiopharmaceuticals
US6534038B2 (en) 2000-04-07 2003-03-18 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US6517814B2 (en) 2001-01-09 2003-02-11 Bristol-Myers Squibb Pharma Company Macrocyclic chelants useful for metallopharmaceuticals
US6776977B2 (en) 2001-01-09 2004-08-17 Bristol-Myers Squibb Pharma Company Polypodal chelants for metallopharmaceuticals
US6794553B2 (en) 2001-11-09 2004-09-21 Shell Oil Company Process for the telomerization of a conjugated diene, catalyst and bidentate ligand useful therein
EP1417977A1 (de) * 2002-11-07 2004-05-12 BRACCO IMAGING S.p.A. Radioaktive Übergangsmetall-Imido-Heterodiphosphinkomplexe; deren Herstellung und radiopharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
CA2039732A1 (en) 1991-03-01
JPH04506810A (ja) 1992-11-26
EP0441953B1 (de) 1995-12-06
JP3341001B2 (ja) 2002-11-05
JP3221875B2 (ja) 2001-10-22
GB8919488D0 (en) 1989-10-11
ATE131072T1 (de) 1995-12-15
JP2002060397A (ja) 2002-02-26
WO1991003262A1 (en) 1991-03-21
DE69024038T2 (de) 1996-04-25
EP0441953A1 (de) 1991-08-21

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation