DE69021886D1 - Äusseres membranprotein p1 und peptide von haemophilus influenzae typ b. - Google Patents
Äusseres membranprotein p1 und peptide von haemophilus influenzae typ b.Info
- Publication number
- DE69021886D1 DE69021886D1 DE69021886T DE69021886T DE69021886D1 DE 69021886 D1 DE69021886 D1 DE 69021886D1 DE 69021886 T DE69021886 T DE 69021886T DE 69021886 T DE69021886 T DE 69021886T DE 69021886 D1 DE69021886 D1 DE 69021886D1
- Authority
- DE
- Germany
- Prior art keywords
- haemophilus influenzae
- protein
- disclosed
- influenzae type
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 4
- 229940045808 haemophilus influenzae type b Drugs 0.000 title abstract 4
- 101710167679 Outer membrane protein P1 Proteins 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 101000846901 Drosophila melanogaster Fat-body protein 1 Proteins 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000746 purification Methods 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000606790 Haemophilus Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000021615 conjugation Effects 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 229940124452 immunizing agent Drugs 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 239000000863 peptide conjugate Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898924473A GB8924473D0 (en) | 1989-10-31 | 1989-10-31 | Outer membrane protein p1 and peptides of haemophilus influenzae b |
| PCT/CA1990/000374 WO1991006652A1 (en) | 1989-10-31 | 1990-10-31 | Outer membrane protein p1 and peptides of haemophilus influenzae type b |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69021886D1 true DE69021886D1 (de) | 1995-09-28 |
| DE69021886T2 DE69021886T2 (de) | 1996-01-11 |
Family
ID=10665452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69021886T Expired - Lifetime DE69021886T2 (de) | 1989-10-31 | 1990-10-31 | Äusseres membranprotein p1 und peptide von haemophilus influenzae typ b. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5985288A (de) |
| EP (1) | EP0500576B1 (de) |
| JP (1) | JP2644625B2 (de) |
| AT (1) | ATE126701T1 (de) |
| CA (1) | CA2072095C (de) |
| DE (1) | DE69021886T2 (de) |
| DK (1) | DK0500576T3 (de) |
| ES (1) | ES2079493T3 (de) |
| GB (1) | GB8924473D0 (de) |
| GR (1) | GR3018208T3 (de) |
| WO (1) | WO1991006652A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843463A (en) * | 1990-12-21 | 1998-12-01 | Antexbiologics, Inc. | Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae |
| DE69130955T2 (de) * | 1990-12-21 | 1999-07-01 | Antex Biologics, Inc., Gaithersburg, Md. | Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza) |
| GB9202219D0 (en) * | 1992-02-03 | 1992-03-18 | Connaught Lab | A synthetic heamophilus influenzae conjugate vaccine |
| GB9224584D0 (en) * | 1992-11-23 | 1993-01-13 | Connaught Lab | Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases |
| US5681570A (en) * | 1995-01-12 | 1997-10-28 | Connaught Laboratories Limited | Immunogenic conjugate molecules |
| US6592776B1 (en) * | 1997-07-28 | 2003-07-15 | Cabot Microelectronics Corporation | Polishing composition for metal CMP |
| US7052860B2 (en) | 2001-11-28 | 2006-05-30 | University Of Florida Research Foundation | Identification of Actinobacillus actinomycetemcomitans antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4673574A (en) * | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
| NZ223009A (en) * | 1986-12-31 | 1990-06-26 | Nl Rivm Of Thoven | Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens |
| GB9202219D0 (en) * | 1992-02-03 | 1992-03-18 | Connaught Lab | A synthetic heamophilus influenzae conjugate vaccine |
-
1989
- 1989-10-31 GB GB898924473A patent/GB8924473D0/en active Pending
-
1990
- 1990-10-31 EP EP90915737A patent/EP0500576B1/de not_active Expired - Lifetime
- 1990-10-31 DE DE69021886T patent/DE69021886T2/de not_active Expired - Lifetime
- 1990-10-31 DK DK90915737.2T patent/DK0500576T3/da active
- 1990-10-31 CA CA002072095A patent/CA2072095C/en not_active Expired - Lifetime
- 1990-10-31 JP JP2514680A patent/JP2644625B2/ja not_active Expired - Lifetime
- 1990-10-31 AT AT90915737T patent/ATE126701T1/de not_active IP Right Cessation
- 1990-10-31 ES ES90915737T patent/ES2079493T3/es not_active Expired - Lifetime
- 1990-10-31 WO PCT/CA1990/000374 patent/WO1991006652A1/en active IP Right Grant
-
1995
- 1995-06-07 US US08/472,172 patent/US5985288A/en not_active Expired - Lifetime
- 1995-11-24 GR GR950401154T patent/GR3018208T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3018208T3 (en) | 1996-02-29 |
| WO1991006652A1 (en) | 1991-05-16 |
| JP2644625B2 (ja) | 1997-08-25 |
| GB8924473D0 (en) | 1989-12-20 |
| DE69021886T2 (de) | 1996-01-11 |
| DK0500576T3 (da) | 1995-09-25 |
| EP0500576B1 (de) | 1995-08-23 |
| ATE126701T1 (de) | 1995-09-15 |
| EP0500576A1 (de) | 1992-09-02 |
| CA2072095C (en) | 1999-09-28 |
| ES2079493T3 (es) | 1996-01-16 |
| US5985288A (en) | 1999-11-16 |
| CA2072095A1 (en) | 1991-05-01 |
| JPH05501202A (ja) | 1993-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |