DE69019512D1 - Verhinderung von verkalkung in bioprosthetischen implantaten. - Google Patents

Verhinderung von verkalkung in bioprosthetischen implantaten.

Info

Publication number
DE69019512D1
DE69019512D1 DE69019512T DE69019512T DE69019512D1 DE 69019512 D1 DE69019512 D1 DE 69019512D1 DE 69019512 T DE69019512 T DE 69019512T DE 69019512 T DE69019512 T DE 69019512T DE 69019512 D1 DE69019512 D1 DE 69019512D1
Authority
DE
Germany
Prior art keywords
preventing calcification
bioprosthetic implants
bioprosthetic
implants
calcification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69019512T
Other languages
English (en)
Other versions
DE69019512T2 (de
Inventor
Alain Carpentier
Sophie Carpentier
Aws Nashef
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/339,787 external-priority patent/US5002566A/en
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of DE69019512D1 publication Critical patent/DE69019512D1/de
Application granted granted Critical
Publication of DE69019512T2 publication Critical patent/DE69019512T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
DE69019512T 1989-02-17 1990-02-01 Verhinderung von verkalkung in bioprosthetischen implantaten. Expired - Lifetime DE69019512T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31254289A 1989-02-17 1989-02-17
US07/339,787 US5002566A (en) 1989-02-17 1989-04-18 Calcification mitigation of bioprosthetic implants
US44408789A 1989-11-30 1989-11-30
PCT/US1990/000639 WO1990009102A1 (en) 1989-02-17 1990-02-01 Calcification mitigation of bioprosthetic implants

Publications (2)

Publication Number Publication Date
DE69019512D1 true DE69019512D1 (de) 1995-06-22
DE69019512T2 DE69019512T2 (de) 1996-02-15

Family

ID=27405604

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69019512T Expired - Lifetime DE69019512T2 (de) 1989-02-17 1990-02-01 Verhinderung von verkalkung in bioprosthetischen implantaten.

Country Status (5)

Country Link
EP (1) EP0458877B1 (de)
JP (1) JPH04503356A (de)
CA (1) CA2046592C (de)
DE (1) DE69019512T2 (de)
WO (1) WO1990009102A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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US5746775A (en) * 1988-04-01 1998-05-05 The Board Of Regent6S Of The University Of Michigan Method of making calcification-resistant bioprosthetic tissue
CA2168283A1 (en) * 1996-01-29 1997-07-30 John Michael Lee Preparation of biological material for implants
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6214054B1 (en) * 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
DE10010074B4 (de) 2000-02-28 2005-04-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen
DE10010073B4 (de) 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerung für implantierbare Herzklappenprothesen
KR100416031B1 (ko) * 2000-10-17 2004-01-31 (주)리젠메드 칼시토닌 및 글루타르알데히드를 첨가하고, 자외선을 조사하여 가교화된 항석회화 돼지심장판막 및 그 제조방법
FR2828263B1 (fr) 2001-08-03 2007-05-11 Philipp Bonhoeffer Dispositif d'implantation d'un implant et procede d'implantation du dispositif
US20040093674A1 (en) * 2002-07-16 2004-05-20 Crystal Cunanan Enhanced phospholipid reduction and calcification mitigation of biological materials
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
DE102005051849B4 (de) 2005-10-28 2010-01-21 JenaValve Technology Inc., Wilmington Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen
DE102005052628B4 (de) 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
CN101720211B (zh) 2007-05-15 2013-06-05 耶拿阀门科技公司 用于操纵导管尖端的手柄、导管系统和用于插入自扩式心脏瓣膜支架的医疗插入系统
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US8465540B2 (en) 2008-02-26 2013-06-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US20100292779A1 (en) 2009-05-15 2010-11-18 Helmut Straubinger Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system
RU2733410C2 (ru) 2009-07-21 2020-10-01 Керикс Байофармасьютикалз, Инк. Лекарственные формы цитрата железа (iii)
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
AU2011257298B2 (en) 2010-05-25 2014-07-31 Jenavalve Technology Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
JP6005168B2 (ja) 2011-10-21 2016-10-12 イエナバルブ テクノロジー インク 患者の身体への拡張型心臓弁ステント導入用カテーテルシステム、カテーテルシステムを備えた挿入システムおよび心臓弁欠陥治療用医療機器
EP2849678B1 (de) 2012-05-16 2022-08-10 JenaValve Technology, Inc. Katheterverabreichungssystem zur einführung einer dehnbaren herzklappenprothese sowie medizinische vorrichtung zur behandlung eines herzklappendefekts
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
EP4098226A1 (de) 2013-08-30 2022-12-07 JenaValve Technology, Inc. Endoprothese mit einem radial zusammenklappbaren rahmen und einer klappenprothese
JP6767388B2 (ja) 2015-05-01 2020-10-14 イェーナヴァルヴ テクノロジー インコーポレイテッド 心臓弁置換におけるペースメーカー割合を低減させるデバイス及び方法
JP7081749B2 (ja) 2016-05-13 2022-06-07 イエナバルブ テクノロジー インク 心臓弁プロテーゼ送達システム
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE492847C (de) * 1926-04-30 1930-02-27 Roehm & Haas Akt Ges Gerbverfahren mit Metallsalzen und kieselsauren Salzen
US4097234A (en) * 1976-12-10 1978-06-27 Nippi, Incorporated Method for preparing dispersion of collagen fiber
US4378224A (en) * 1980-09-19 1983-03-29 Nimni Marcel E Coating for bioprosthetic device and method of making same
FR2523810B1 (fr) * 1982-03-23 1988-11-25 Carpentier Alain Tissu biologique greffable et procede pour sa preparation
US4402697A (en) * 1982-08-25 1983-09-06 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
US4405327A (en) * 1982-08-25 1983-09-20 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
EP0172716A1 (de) * 1984-08-14 1986-02-26 Shiley Incorporated Verhinderung von Verkalkung in implantierbaren Geweben mit Hilfe von oberflächenaktiven Betainen
US4729139A (en) * 1985-11-05 1988-03-08 Baxter Travenol Selective incorporation of a polymer into implantable biological tissue to inhibit calcification

Also Published As

Publication number Publication date
EP0458877A1 (de) 1991-12-04
WO1990009102A1 (en) 1990-08-23
JPH04503356A (ja) 1992-06-18
DE69019512T2 (de) 1996-02-15
CA2046592C (en) 2000-05-02
CA2046592A1 (en) 1990-08-18
EP0458877B1 (de) 1995-05-17

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