DE69015270T2 - Cyclische vinyloge N-hydroxy-N-methylharnstoffe verwendbar als 5-Lipoygenase-Inhibitoren. - Google Patents
Cyclische vinyloge N-hydroxy-N-methylharnstoffe verwendbar als 5-Lipoygenase-Inhibitoren.Info
- Publication number
- DE69015270T2 DE69015270T2 DE69015270T DE69015270T DE69015270T2 DE 69015270 T2 DE69015270 T2 DE 69015270T2 DE 69015270 T DE69015270 T DE 69015270T DE 69015270 T DE69015270 T DE 69015270T DE 69015270 T2 DE69015270 T2 DE 69015270T2
- Authority
- DE
- Germany
- Prior art keywords
- methylureas
- hydroxy
- lipoygenase
- inhibitors
- usable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/380,937 US5026861A (en) | 1989-07-17 | 1989-07-17 | Substituted 1,5-dihydro-4-(N-methylhydroxylamino)-2H-pyrrol-2-ones |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69015270D1 DE69015270D1 (de) | 1995-02-02 |
DE69015270T2 true DE69015270T2 (de) | 1995-06-08 |
Family
ID=23503027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69015270T Expired - Fee Related DE69015270T2 (de) | 1989-07-17 | 1990-07-17 | Cyclische vinyloge N-hydroxy-N-methylharnstoffe verwendbar als 5-Lipoygenase-Inhibitoren. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5026861A (de) |
EP (1) | EP0409163B1 (de) |
JP (1) | JP2879464B2 (de) |
AT (1) | ATE115948T1 (de) |
AU (1) | AU627339B2 (de) |
CA (1) | CA2021340C (de) |
DE (1) | DE69015270T2 (de) |
DK (1) | DK0409163T3 (de) |
ES (1) | ES2068952T3 (de) |
GR (1) | GR3015458T3 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5109010A (en) * | 1989-07-17 | 1992-04-28 | Merrell Dow Pharmaceuticals Inc. | Dibenzofuranyl substituted 1,5-dihydro-4-(N-methylhydroxylamino)-2H-pyrrol-2-ones |
DE4213919A1 (de) * | 1992-04-28 | 1993-11-04 | Thomae Gmbh Dr K | Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE4213931A1 (de) * | 1992-04-28 | 1993-11-04 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US7937897B2 (en) * | 2006-01-25 | 2011-05-10 | Yusenkaisha Japan Isusyc | Dome-shaped shelter |
WO2010067085A2 (en) * | 2008-12-12 | 2010-06-17 | Wista Laboratories Ltd. | Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-υ-carboline and analogues and intermediates |
CN103384563B (zh) | 2011-02-21 | 2015-04-22 | 佳能株式会社 | 热处理设备及制造调色剂的方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0623194B2 (ja) * | 1985-03-23 | 1994-03-30 | 鐘淵化学工業株式会社 | 新規ラクタム誘導体及び抗炎症剤 |
JPS63115859A (ja) * | 1986-10-31 | 1988-05-20 | Eisai Co Ltd | 2−ピロリドン誘導体を含有する抗炎症剤 |
-
1989
- 1989-07-17 US US07/380,937 patent/US5026861A/en not_active Expired - Fee Related
-
1990
- 1990-07-16 AU AU59001/90A patent/AU627339B2/en not_active Ceased
- 1990-07-17 EP EP90113677A patent/EP0409163B1/de not_active Expired - Lifetime
- 1990-07-17 ES ES90113677T patent/ES2068952T3/es not_active Expired - Lifetime
- 1990-07-17 DE DE69015270T patent/DE69015270T2/de not_active Expired - Fee Related
- 1990-07-17 CA CA002021340A patent/CA2021340C/en not_active Expired - Fee Related
- 1990-07-17 DK DK90113677.0T patent/DK0409163T3/da active
- 1990-07-17 JP JP2187355A patent/JP2879464B2/ja not_active Expired - Fee Related
- 1990-07-17 AT AT90113677T patent/ATE115948T1/de not_active IP Right Cessation
-
1995
- 1995-03-20 GR GR950400589T patent/GR3015458T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE115948T1 (de) | 1995-01-15 |
CA2021340A1 (en) | 1991-01-18 |
CA2021340C (en) | 2001-01-23 |
JP2879464B2 (ja) | 1999-04-05 |
DK0409163T3 (da) | 1995-02-20 |
ES2068952T3 (es) | 1995-05-01 |
GR3015458T3 (en) | 1995-06-30 |
EP0409163B1 (de) | 1994-12-21 |
AU5900190A (en) | 1991-01-17 |
EP0409163A2 (de) | 1991-01-23 |
AU627339B2 (en) | 1992-08-20 |
EP0409163A3 (en) | 1991-03-20 |
JPH0352858A (ja) | 1991-03-07 |
DE69015270D1 (de) | 1995-02-02 |
US5026861A (en) | 1991-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |