DE69011531D1 - Von faktor vii abgeleitete peptide mit antihämostatischer wirkung. - Google Patents
Von faktor vii abgeleitete peptide mit antihämostatischer wirkung.Info
- Publication number
- DE69011531D1 DE69011531D1 DE69011531T DE69011531T DE69011531D1 DE 69011531 D1 DE69011531 D1 DE 69011531D1 DE 69011531 T DE69011531 T DE 69011531T DE 69011531 T DE69011531 T DE 69011531T DE 69011531 D1 DE69011531 D1 DE 69011531D1
- Authority
- DE
- Germany
- Prior art keywords
- factor vii
- peptides derived
- hemostatic effect
- peptides
- factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6437—Coagulation factor VIIa (3.4.21.21)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/435,657 US5190919A (en) | 1989-11-13 | 1989-11-13 | Antihemostatic factor vii peptides |
PCT/US1990/006617 WO1991007432A1 (en) | 1989-11-13 | 1990-11-13 | Antihemostatic factor vii peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69011531D1 true DE69011531D1 (de) | 1994-09-15 |
DE69011531T2 DE69011531T2 (de) | 1994-12-08 |
Family
ID=23729271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69011531T Expired - Fee Related DE69011531T2 (de) | 1989-11-13 | 1990-11-13 | Von faktor vii abgeleitete peptide mit antihämostatischer wirkung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5190919A (de) |
EP (1) | EP0500800B1 (de) |
AT (1) | ATE109794T1 (de) |
AU (1) | AU6963491A (de) |
DE (1) | DE69011531T2 (de) |
DK (1) | DK0500800T3 (de) |
WO (1) | WO1991007432A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5506134A (en) * | 1990-10-22 | 1996-04-09 | Corvas International, Inc. | Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex |
US5997864A (en) * | 1995-06-07 | 1999-12-07 | Novo Nordisk A/S | Modified factor VII |
US5817788A (en) * | 1991-02-28 | 1998-10-06 | Zymogenetics, Inc. | Modified factor VII |
US5833982A (en) | 1991-02-28 | 1998-11-10 | Zymogenetics, Inc. | Modified factor VII |
US5861374A (en) * | 1991-02-28 | 1999-01-19 | Novo Nordisk A/S | Modified Factor VII |
US5788965A (en) * | 1991-02-28 | 1998-08-04 | Novo Nordisk A/S | Modified factor VII |
CA2105863A1 (en) * | 1991-03-11 | 1992-09-12 | Guy L. Reed | Compositions and methods to inhibit the activation of active factor xiii |
JP3180824B2 (ja) * | 1991-08-30 | 2001-06-25 | シスメックス株式会社 | 血液凝固試薬 |
US6039944A (en) * | 1992-02-28 | 2000-03-21 | Zymogenetics, Inc. | Modified Factor VII |
WO1993018782A1 (en) * | 1992-03-20 | 1993-09-30 | Cor Therapeutics, Inc. | Glycosylation-mediated inhibition of factor x |
GB9425381D0 (en) * | 1994-12-15 | 1995-02-15 | Nycomed Pharma As | Peptides |
EP0987274A1 (de) | 1998-09-15 | 2000-03-22 | Hoechst Marion Roussel Deutschland GmbH | Faktor VIIa Inhibitore |
JP2003530819A (ja) | 1999-06-14 | 2003-10-21 | ノボ ノルディスク アクティーゼルスカブ | FVIIa/TF活性阻害化合物 |
ES2856968T3 (es) | 2016-01-15 | 2021-09-28 | Rigshospitalet | Adquisición de imágenes de TEP cuantitativas de la expresión de factor tisular usando factor VII inhibido en el punto activo y marcado con 18F |
MA46864A (fr) | 2016-11-17 | 2021-04-28 | Minerva Imaging Aps | Facteur vii inhibé par le site actif marqué par 177-lu |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8305985D0 (en) * | 1983-03-04 | 1983-04-07 | Szelke M | Enzyme inhibition |
DE3533516A1 (de) * | 1984-09-21 | 1986-04-03 | Boehringer Ingelheim KG, 6507 Ingelheim | Blutgerinnungshemmende proteine, verfahren zur herstellung sowie deren verwendung |
EP0209061B1 (de) * | 1985-07-17 | 1994-01-12 | Hoechst Aktiengesellschaft | Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel |
EP0391999A4 (en) * | 1988-09-23 | 1991-03-13 | Corvas, Inc. | Peptidyl inhibitors of the initiation of coagulation |
-
1989
- 1989-11-13 US US07/435,657 patent/US5190919A/en not_active Expired - Fee Related
-
1990
- 1990-11-13 WO PCT/US1990/006617 patent/WO1991007432A1/en active IP Right Grant
- 1990-11-13 AT AT91901068T patent/ATE109794T1/de not_active IP Right Cessation
- 1990-11-13 DK DK91901068.6T patent/DK0500800T3/da active
- 1990-11-13 AU AU69634/91A patent/AU6963491A/en not_active Abandoned
- 1990-11-13 DE DE69011531T patent/DE69011531T2/de not_active Expired - Fee Related
- 1990-11-13 EP EP91901068A patent/EP0500800B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0500800A1 (de) | 1992-09-02 |
EP0500800B1 (de) | 1994-08-10 |
DE69011531T2 (de) | 1994-12-08 |
ATE109794T1 (de) | 1994-08-15 |
WO1991007432A1 (en) | 1991-05-30 |
DK0500800T3 (da) | 1994-12-05 |
US5190919A (en) | 1993-03-02 |
AU6963491A (en) | 1991-06-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |