DE69005620D1 - Polypeptide mit einer aktivität des menschlichen beta-andrenergischen rezeptors, einbezogen in die lipolytische antwort, deren nukleinsäuresequenzen. - Google Patents

Polypeptide mit einer aktivität des menschlichen beta-andrenergischen rezeptors, einbezogen in die lipolytische antwort, deren nukleinsäuresequenzen.

Info

Publication number
DE69005620D1
DE69005620D1 DE90902296T DE69005620T DE69005620D1 DE 69005620 D1 DE69005620 D1 DE 69005620D1 DE 90902296 T DE90902296 T DE 90902296T DE 69005620 T DE69005620 T DE 69005620T DE 69005620 D1 DE69005620 D1 DE 69005620D1
Authority
DE
Germany
Prior art keywords
polypeptides
pct
fragment
beta
lipolytic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE90902296T
Other languages
English (en)
Other versions
DE69005620T2 (de
Inventor
Laurent Emorine
Stefano Marullo
Donny Strosberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
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Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of DE69005620D1 publication Critical patent/DE69005620D1/de
Application granted granted Critical
Publication of DE69005620T2 publication Critical patent/DE69005620T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69005620T 1989-01-25 1990-01-25 Polypeptide mit einer aktivität des menschlichen beta-andrenergischen rezeptors, einbezogen in die lipolytische antwort, deren nukleinsäuresequenzen. Expired - Lifetime DE69005620T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8900918A FR2642075B1 (fr) 1989-01-25 1989-01-25 Polypeptides ayant une activite de recepteur (beta)-adrenergique chez l'homme, impliques dans la reponse lipolytique, acides nucleiques codant pour ces polypeptides et utilisation de ces polypeptides pour le criblage de substance active sur ces polypeptides
PCT/FR1990/000054 WO1990008775A1 (fr) 1989-01-25 1990-01-25 POLYPEPTIDES AYANT UNE ACTIVITE DE RECEPTEUR β ADRENERGIQUE CHEZ L'HOMME, IMPLIQUES DANS LA REPONSE LIPOLYTIQUE, ACIDES NUCLEIQUES CODANT POUR CES POLYPEPTIDES ET UTILISATION DE CES POLYPEPTIDES POUR LE CRIBLAGE DE SUBSTANCE ACTIVE SUR CES POLYPEPTIDES

Publications (2)

Publication Number Publication Date
DE69005620D1 true DE69005620D1 (de) 1994-02-10
DE69005620T2 DE69005620T2 (de) 1994-07-21

Family

ID=9378098

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69005620T Expired - Lifetime DE69005620T2 (de) 1989-01-25 1990-01-25 Polypeptide mit einer aktivität des menschlichen beta-andrenergischen rezeptors, einbezogen in die lipolytische antwort, deren nukleinsäuresequenzen.

Country Status (10)

Country Link
US (1) US5288607A (de)
EP (1) EP0455682B1 (de)
JP (1) JP3050238B2 (de)
AT (1) ATE99328T1 (de)
CA (1) CA2045658C (de)
DE (1) DE69005620T2 (de)
DK (1) DK0455682T3 (de)
ES (1) ES2062508T3 (de)
FR (1) FR2642075B1 (de)
WO (1) WO1990008775A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635442B1 (en) 1989-01-25 2003-10-21 Centre National De La Recherche Scientific Intron/exon structure of the human and mouse β3-adrenergic receptor genes
US6274706B1 (en) 1989-01-25 2001-08-14 Centre National De La Recherche Scientifique Intron/exon of the human and mouse beta 3-adrenergic receptor genes
US5840836A (en) * 1989-02-17 1998-11-24 Bayer Corporation Pancreatic islet cell antigens obtained by molecular cloning
US6811989B1 (en) * 1989-02-17 2004-11-02 Bayer Corporation Pancreatic islet cell antigens obtained by molecular cloning
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
US5155218A (en) 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
IT1252444B (it) * 1990-09-07 1995-06-16 Enichem Spa Metodo per l'identificazione e/o l'isolamento di geni che codificano per recettori di membrana.
FR2671559B1 (fr) * 1991-01-14 2002-09-27 Ct Nal Rech Scient Sequences codant pour le recepteur beta3-adrenergique murin, leur utilisation comme sondes et pour l'expression de peptides, vecteurs, hotes cellulaires contenant ledit vecteur, et applications desdits peptides.
US5418160A (en) * 1991-11-01 1995-05-23 The United States As Represented By The Secretary Of The Department Of Health And Human Services Cloned cell line expressing rat β3A adrenergic receptor
US5364772A (en) * 1992-07-20 1994-11-15 Wayne State University DNA molecule encoding the β3 -adrenergic receptor
US5455461A (en) * 1992-09-21 1995-10-03 Fujitsu Limited Semiconductor device having reformed pad
DE69232486T2 (de) * 1992-12-01 2002-10-31 Centre National De La Recherche Scientifique, Paris Intron/Exon Struktur der Genen von den menschlichen und Maus Beta 3 adrenergischen Rezeptoren
FR2704235B1 (fr) * 1993-04-21 1995-06-23 Vetigen Sarl Séquences nucléotidiques codant pour le récepteur beta3-adrénergique (RAbeta3) bovin et leurs applications.
US5843652A (en) * 1993-05-21 1998-12-01 Lockheed Martin Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
DE69431672T2 (de) * 1994-08-10 2003-09-18 Human Genome Sciences, Inc. Adrenergischer rezeptor
US5817477A (en) * 1995-06-06 1998-10-06 Human Genome Sciences, Inc. Adrenergic receptor
JPH10508486A (ja) * 1994-11-07 1998-08-25 メルク エンド カンパニー インコーポレーテッド 修飾神経ペプチドｙレセプター
US5766851A (en) * 1995-05-19 1998-06-16 The Johns Hopkins University School Of Medicine Susceptibility gene for obesity and type II diabetes mellitus
FR2746813B1 (fr) * 1996-03-26 1998-05-07 Vetigen Sarl Sequences codant pour les recepteurs beta2- et beta3- adrenergiques canins et leurs applications en tant que sondes et pour l'expression de peptides
US5789654A (en) * 1996-05-09 1998-08-04 Beth Israel Hospital Association Transgenic animals deficient in endogenous β3 -adrenergic receptor and uses thereof
EP1298209A4 (de) * 2000-06-20 2006-03-01 Chugai Res Inst Molecular Med TRANSKRIPTIONSFAKTOR MIT ZINKFINGERDOMäNE
EP1303543A1 (de) * 2000-07-17 2003-04-23 Univation Technologies LLC Katalysatorsystem und seine verwendung in einem polymerisationsverfahren
EP1684593A4 (de) * 2003-11-20 2010-02-10 Alteragon Pty Ltd Verfahren zur verringerung von fettablagerungen sowie des körpergewichts bei säugetieren und vögeln
EP1947103A1 (de) 2007-01-22 2008-07-23 4Sc Ag Aryloxypropanolamine, Herstellungsverfahren dafür und Verwendung von Aryloxypropanolaminen als Arzneimittel

Also Published As

Publication number Publication date
WO1990008775A1 (fr) 1990-08-09
ATE99328T1 (de) 1994-01-15
CA2045658A1 (fr) 1990-07-26
US5288607A (en) 1994-02-22
CA2045658C (fr) 2000-01-04
FR2642075A1 (fr) 1990-07-27
DK0455682T3 (da) 1994-01-31
FR2642075B1 (fr) 1991-04-26
JP3050238B2 (ja) 2000-06-12
EP0455682B1 (de) 1993-12-29
JPH04504354A (ja) 1992-08-06
DE69005620T2 (de) 1994-07-21
ES2062508T3 (es) 1994-12-16
EP0455682A1 (de) 1991-11-13

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