DE69005297D1 - Metastasenzugehörige kollagenolytische metalloproteinase. - Google Patents

Metastasenzugehörige kollagenolytische metalloproteinase.

Info

Publication number
DE69005297D1
DE69005297D1 DE90903555T DE69005297T DE69005297D1 DE 69005297 D1 DE69005297 D1 DE 69005297D1 DE 90903555 T DE90903555 T DE 90903555T DE 69005297 T DE69005297 T DE 69005297T DE 69005297 D1 DE69005297 D1 DE 69005297D1
Authority
DE
Germany
Prior art keywords
enzyme
disclosed
found
collagenolytic
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90903555T
Other languages
English (en)
Other versions
DE69005297T2 (de
Inventor
Motowa Nakajima
Garth Nicolson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of DE69005297D1 publication Critical patent/DE69005297D1/de
Application granted granted Critical
Publication of DE69005297T2 publication Critical patent/DE69005297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE90903555T 1989-02-27 1990-01-29 Metastasenzugehörige kollagenolytische metalloproteinase. Expired - Fee Related DE69005297T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31626089A 1989-02-27 1989-02-27
PCT/US1990/000506 WO1990010062A1 (en) 1989-02-27 1990-01-29 Metastasis-associated collagenolytic metalloproteinases

Publications (2)

Publication Number Publication Date
DE69005297D1 true DE69005297D1 (de) 1994-01-27
DE69005297T2 DE69005297T2 (de) 1994-04-21

Family

ID=23228283

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90903555T Expired - Fee Related DE69005297T2 (de) 1989-02-27 1990-01-29 Metastasenzugehörige kollagenolytische metalloproteinase.

Country Status (9)

Country Link
EP (1) EP0460016B1 (de)
JP (1) JPH04505699A (de)
AT (1) ATE98685T1 (de)
AU (1) AU639906B2 (de)
CA (1) CA2048695A1 (de)
DE (1) DE69005297T2 (de)
DK (1) DK0460016T3 (de)
ES (1) ES2060146T3 (de)
WO (1) WO1990010062A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324634A (en) * 1992-03-31 1994-06-28 The Research Foundation Of State University Of New York Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer
WO1994005807A1 (en) * 1992-08-28 1994-03-17 Dickson Robert B Matrix-degrading metalloproteinase
WO1997009420A2 (en) * 1995-09-05 1997-03-13 Celltech Therapeutics Limited Dna sequences coding for a human metalloproteinase and variants thereof
US7041787B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
US20130217034A1 (en) 2010-08-13 2013-08-22 Dentognostics Gmbh Process for avoiding false positive results in a detecting process of an inflammation indicator in a rinse solution for taking up gingival crevicular fluid

Also Published As

Publication number Publication date
DE69005297T2 (de) 1994-04-21
WO1990010062A1 (en) 1990-09-07
AU5104790A (en) 1990-09-26
ATE98685T1 (de) 1994-01-15
DK0460016T3 (da) 1994-04-25
EP0460016B1 (de) 1993-12-15
ES2060146T3 (es) 1994-11-16
AU639906B2 (en) 1993-08-12
EP0460016A1 (de) 1991-12-11
JPH04505699A (ja) 1992-10-08
CA2048695A1 (en) 1990-09-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee