DE68929141D1 - Krebszellenmetastaseninhibitoren - Google Patents

Krebszellenmetastaseninhibitoren

Info

Publication number
DE68929141D1
DE68929141D1 DE68929141T DE68929141T DE68929141D1 DE 68929141 D1 DE68929141 D1 DE 68929141D1 DE 68929141 T DE68929141 T DE 68929141T DE 68929141 T DE68929141 T DE 68929141T DE 68929141 D1 DE68929141 D1 DE 68929141D1
Authority
DE
Germany
Prior art keywords
cancer cell
cell metastasis
metastasis inhibitors
inhibitors
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68929141T
Other languages
English (en)
Inventor
Tsutomu Tsuruoka
Satoru Nakabayashi
Harumi Fukuyasu
Yuuko Ishii
Takashi Tsuruoka
Haruo Yamamoto
Shigeharu Inouye
Shinichi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3109588A external-priority patent/JPH0643306B2/ja
Priority claimed from JP9367388A external-priority patent/JPH078793B2/ja
Priority claimed from JP9745488A external-priority patent/JPH078794B2/ja
Priority claimed from JP63147816A external-priority patent/JPH0768215B2/ja
Priority claimed from JP14781588A external-priority patent/JPH01313425A/ja
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of DE68929141D1 publication Critical patent/DE68929141D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68929141T 1988-02-12 1989-02-09 Krebszellenmetastaseninhibitoren Expired - Lifetime DE68929141D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP3109588A JPH0643306B2 (ja) 1988-02-12 1988-02-12 癌細胞転移抑制剤
JP9367388A JPH078793B2 (ja) 1988-04-15 1988-04-15 Ｎ−置換−１−デオキシノジリマイシン誘導体を含有する癌細胞転移抑制剤
JP9745488A JPH078794B2 (ja) 1988-04-19 1988-04-19 糖ラクタムを含有する癌細胞転移抑制剤
JP63147816A JPH0768215B2 (ja) 1988-06-14 1988-06-14 糖ラクタム誘導体
JP14781588A JPH01313425A (ja) 1988-06-14 1988-06-14 糖ラクタム誘導体及びそれを含有する癌細胞転移抑制剤

Publications (1)

Publication Number Publication Date
DE68929141D1 true DE68929141D1 (de) 2000-02-24

Family

ID=27521295

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68929141T Expired - Lifetime DE68929141D1 (de) 1988-02-12 1989-02-09 Krebszellenmetastaseninhibitoren

Country Status (3)

Country Link
US (1) US4985445A (de)
EP (1) EP0328111B1 (de)
DE (1) DE68929141D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2065446A1 (en) * 1989-09-07 1991-03-08 Yoshiaki Yoshikuni Antiviral drug
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
WO2000056334A1 (en) * 1999-03-19 2000-09-28 The Trustees Of Boston College Use of imino sugars for anti-tumor therapy
WO2004007407A2 (en) * 2002-07-11 2004-01-22 Fluorous Technologies Incorporated Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
WO2004074251A1 (en) * 2003-02-20 2004-09-02 Ranbaxy Laboratories Limited Derivatives of azasugars as anticancer agents
US8415315B2 (en) 2004-05-06 2013-04-09 University Of Central Florida Research Foundation, Inc. Methods and compositions for inhibiting the proliferation of cancer cells
ES2705335T3 (es) * 2005-05-17 2019-03-22 Amicus Therapeutics Inc Un método para el tratamiento de la enfermedad de Pompe usando 1-desoxinojirimicina y derivados
US8975280B2 (en) * 2006-05-24 2015-03-10 The Chancellor, Masters And Scholars Of The University Of Oxford Deoxynojirimycin and D-arabinitol analogs and methods of using
JP6236406B2 (ja) 2012-03-07 2017-11-22 アミカス セラピューティックス インコーポレイテッド ポンペ病の処置のための高濃度α−グルコシダーゼ組成物
CN114540327A (zh) 2014-09-30 2022-05-27 阿米库斯治疗学公司 具有增强的碳水化合物的高强度酸性α-葡糖苷酶
WO2017117407A1 (en) 2015-12-30 2017-07-06 Amicus Therapeutics, Inc. Augmented acid alpha-glucosidase for the treatment of pompe disease
CA3019354A1 (en) 2016-03-30 2017-10-05 Amicus Therapeutics, Inc. Method for selection of high m6p recombinant proteins
SG11201808455VA (en) 2016-03-30 2018-10-30 Amicus Therapeutics Inc Formulations comprising recombinant acid alpha-glucosidase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5617349B2 (de) * 1973-07-09 1981-04-22
JPS5953261B2 (ja) * 1973-08-03 1984-12-24 明治製菓株式会社 ２（１ｈ）−ピリドン誘導体の製造法
JPS5833229B2 (ja) * 1974-03-28 1983-07-18 明治製菓株式会社 Ｄ− グルコ −１，５− ラクタムユウドウタイ ノ セイホウ
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
JPS55105666A (en) * 1979-02-08 1980-08-13 Nippon Shinyaku Co Ltd Piperidine derivative
JPS55105667A (en) * 1979-02-08 1980-08-13 Nippon Shinyaku Co Ltd Gluconic lactam derivative
DE3007078A1 (de) * 1980-02-26 1981-09-10 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JPH0676379B2 (ja) * 1987-03-06 1994-09-28 明治製菓株式会社 糖ラクタム誘導体及びそれを含有する抗炎症剤
JPH0676324B2 (ja) * 1987-04-15 1994-09-28 明治製菓株式会社 糖ラクタムを含有する抗炎症剤
JPH0761945B2 (ja) * 1988-04-26 1995-07-05 明治製菓株式会社 癌細胞転移抑制剤
EP0345104B1 (de) * 1988-06-02 1995-11-02 Merrell Dow Pharmaceuticals Inc. Alpha-glukosidase-Inhibitoren

Also Published As

Publication number Publication date
EP0328111B1 (de) 2000-01-19
EP0328111A3 (de) 1993-03-24
US4985445A (en) 1991-01-15
EP0328111A2 (de) 1989-08-16

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Legal Events

Date Code Title Description
8332 No legal effect for de