DE68928933D1 - Faser-hemagglutinin von b. pertussis - Google Patents

Faser-hemagglutinin von b. pertussis

Info

Publication number
DE68928933D1
DE68928933D1 DE68928933T DE68928933T DE68928933D1 DE 68928933 D1 DE68928933 D1 DE 68928933D1 DE 68928933 T DE68928933 T DE 68928933T DE 68928933 T DE68928933 T DE 68928933T DE 68928933 D1 DE68928933 D1 DE 68928933D1
Authority
DE
Germany
Prior art keywords
pertussis
therapy
hemagglutinine
fiber
filamentous hemagglutinin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928933T
Other languages
English (en)
Other versions
DE68928933T2 (de
Inventor
David Relman
Mario Domenighini
Rino Rappuoli
Stanley Falkow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sclavo SpA
Leland Stanford Junior University
Original Assignee
Sclavo SpA
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo SpA, Leland Stanford Junior University filed Critical Sclavo SpA
Publication of DE68928933D1 publication Critical patent/DE68928933D1/de
Application granted granted Critical
Publication of DE68928933T2 publication Critical patent/DE68928933T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/127—RNA-directed RNA polymerase (2.7.7.48), i.e. RNA replicase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Rotary Switch, Piano Key Switch, And Lever Switch (AREA)
  • Insulated Conductors (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE68928933T 1988-10-27 1989-10-20 Faser-hemagglutinin von b. pertussis Expired - Fee Related DE68928933T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26364888A 1988-10-27 1988-10-27
PCT/US1989/004732 WO1990004641A1 (en) 1988-10-27 1989-10-20 FILAMENTOUS HEMAGGLUTININ OF $i(B. PERTUSSIS)

Publications (2)

Publication Number Publication Date
DE68928933D1 true DE68928933D1 (de) 1999-04-01
DE68928933T2 DE68928933T2 (de) 1999-08-26

Family

ID=23002666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928933T Expired - Fee Related DE68928933T2 (de) 1988-10-27 1989-10-20 Faser-hemagglutinin von b. pertussis

Country Status (9)

Country Link
EP (1) EP0439542B1 (de)
JP (1) JPH04501506A (de)
AT (1) ATE176913T1 (de)
AU (1) AU643190B2 (de)
CA (1) CA1341123C (de)
DE (1) DE68928933T2 (de)
DK (1) DK76191A (de)
FI (1) FI911973A0 (de)
WO (1) WO1990004641A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643753A (en) 1990-04-18 1997-07-01 Connaught Laboratories Limited Use of autologous promoters to express gene products in bordetella
GB9008746D0 (en) * 1990-04-18 1990-06-13 Connaught Lab The use of autologous promoters to express gene products in bordetella
DE4111531A1 (de) * 1991-04-09 1992-10-29 Biotechnolog Forschung Gmbh Plasmide zur fha-expression und wirte
WO1994021816A1 (en) * 1993-03-25 1994-09-29 Envirocon International Incorporated Test kits and methods for rapidly testing for contamination by microorganisms
US5646251A (en) * 1993-11-05 1997-07-08 The Board Of Trustees Of Leeland Stanford Jr. Univ. Alloreaction-associated antigen (ARAG): a novel member of the immunoglobulin gene superfamily
FR2718750B1 (fr) * 1994-04-19 1996-06-14 Pasteur Institut Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
EP1069133A1 (de) 1999-07-13 2001-01-17 Institut National De La Sante Et De La Recherche Medicale (Inserm) Neisseria meningitidis Zusammensetzungen und ihre Verwendungen als anti-infektionsmitteln
ITMI20090946A1 (it) 2009-05-28 2010-11-29 Novartis Ag Espressione di proteine ricombinanti
US8916173B2 (en) 2013-03-08 2014-12-23 Crucell Holland B.V. Acellular pertussis vaccine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6176422A (ja) * 1984-09-22 1986-04-18 Chemo Sero Therapeut Res Inst 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法
FR2590483B1 (fr) * 1985-11-22 1988-12-09 Pasteur Institut Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine

Also Published As

Publication number Publication date
ATE176913T1 (de) 1999-03-15
EP0439542A4 (en) 1991-11-06
JPH04501506A (ja) 1992-03-19
WO1990004641A1 (en) 1990-05-03
AU643190B2 (en) 1993-11-11
DK76191D0 (da) 1991-04-25
EP0439542A1 (de) 1991-08-07
CA1341123C (en) 2000-10-17
EP0439542B1 (de) 1999-02-24
DE68928933T2 (de) 1999-08-26
FI911973A0 (fi) 1991-04-23
AU4515589A (en) 1990-05-14
DK76191A (da) 1991-06-14

Similar Documents

Publication Publication Date Title
IT8224948A0 (it) Virus vaccinico modificato e metodi per la produzione ed uso del medesimo.
SE9002522L (sv) Metod foer framstaellning av en farmaceutisk komposition i form av mikropartiklar
ES487106A0 (es) Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv
DK0835133T3 (da) Rekombinant koppevirus-rabies-præparater og kombinationspræparater samt anvendelser deraf
IT8819077A0 (it) Processo per la preparazione di 1,2 difluoroetano e di 1,1,2trifluoroetano.
ES2109254T3 (es) Proteinas antigenas y vacunas que las contienen para la prevencion de cocidiosis.
NO912825D0 (no) Fremgangsmaate for fremstilling av cokonjugate vaksiner omfattende immunogenisk protein, hiv-beslektede peptider og anioniske grupper.
NO904471D0 (no) Fremgangsmaate for fremstilling av partikkelformig titandioxyd.
DK0909323T3 (da) Helicobacter pylori-bakterioferritin
DE68928933D1 (de) Faser-hemagglutinin von b. pertussis
DE3854387D1 (de) Einschlusskomplex von Nicardipin oder seinem Hydrochlorid mit beta-Cyclodextrin, ein Verfahren zur Herstellung desselben und eine diesen enthaltende pharmazeutische Zubereitung mit verzögerter Wirkung.
ATE422900T1 (de) Verfahren zur herstellung eines azellulären impfstoffes der bordetella pertussis antigene enthält
DE69017608D1 (de) Verfahren für die Bestimmung von Distickstoffoxid.
SE8902148D0 (sv) Syntetiska peptid antigen foer detektion av htlv-1 infektion
DE68914042D1 (de) Verfahren zur Herstellung von Polyfluorokohlenwasserstoffiodid.
DE58906693D1 (de) Verfahren zur Herstellung von Pigmentzubereitungen der Anthanthronreihe.
DK203485A (da) Taetningsmasse og fremgangsmaade til fremstilling deraf
DE68912734D1 (de) Verfahren zur Herstellung von Tetrafluoräthylen.
DE69013132D1 (de) Verfahren zur Herstellung von Octa-2,7-dien-1-ol.
HU9200583D0 (en) Method for producing el peptides of rubeola
DE68912809D1 (de) Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin.
DE69013621D1 (de) Verfahren zur Herstellung von tertiärem Amino-Alkohol.
DE69009394D1 (de) Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethyl-1-cyclohexanon.
DE58905605D1 (de) Verfahren zur Herstellung von cyclischen Harnstoffen.
DE3686684D1 (de) Mittel zur absorptionsverbesserung von proteinen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee