DE68927636D1 - Photochemische Umwandlung von Cephalosporinen, 1-Carba(dethia)cephalosporinen und 1-Oxa(1-dethia)cephalosporinen - Google Patents

Photochemische Umwandlung von Cephalosporinen, 1-Carba(dethia)cephalosporinen und 1-Oxa(1-dethia)cephalosporinen

Info

Publication number
DE68927636D1
DE68927636D1 DE68927636T DE68927636T DE68927636D1 DE 68927636 D1 DE68927636 D1 DE 68927636D1 DE 68927636 T DE68927636 T DE 68927636T DE 68927636 T DE68927636 T DE 68927636T DE 68927636 D1 DE68927636 D1 DE 68927636D1
Authority
DE
Germany
Prior art keywords
cephalosporins
dethia
carba
oxa
photochemical conversion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927636T
Other languages
English (en)
Other versions
DE68927636T2 (de
Inventor
Larry Wayne Hertel
John Michael Morin
Robert Theodore Vasileff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE68927636D1 publication Critical patent/DE68927636D1/de
Publication of DE68927636T2 publication Critical patent/DE68927636T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
    • B01J19/122—Incoherent waves
    • B01J19/123—Ultraviolet light
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D463/08—Modification of a carboxyl group directly attached in position 2, e.g. esterification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Electromagnetism (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE68927636T 1989-03-15 1989-12-08 Photochemische Umwandlung von Cephalosporinen, 1-Carba(dethia)cephalosporinen und 1-Oxa(1-dethia)cephalosporinen Expired - Fee Related DE68927636T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,169 US4888100A (en) 1989-03-15 1989-03-15 Photochemical conversion of cephalosporins, 1-carba(1-dethia)cephalosporins and 1-oxa(1-dethia)cephalosporins

Publications (2)

Publication Number Publication Date
DE68927636D1 true DE68927636D1 (de) 1997-02-20
DE68927636T2 DE68927636T2 (de) 1997-05-28

Family

ID=23262398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927636T Expired - Fee Related DE68927636T2 (de) 1989-03-15 1989-12-08 Photochemische Umwandlung von Cephalosporinen, 1-Carba(dethia)cephalosporinen und 1-Oxa(1-dethia)cephalosporinen

Country Status (12)

Country Link
US (1) US4888100A (de)
EP (1) EP0387448B1 (de)
JP (1) JPH02268188A (de)
KR (1) KR900014402A (de)
AT (1) ATE147389T1 (de)
CA (1) CA2005166A1 (de)
DE (1) DE68927636T2 (de)
ES (1) ES2095843T3 (de)
GR (1) GR3022830T3 (de)
HU (1) HU206360B (de)
IL (1) IL92623A (de)
MX (1) MX18633A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60187689A (ja) * 1984-03-06 1985-09-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造法

Also Published As

Publication number Publication date
EP0387448A3 (de) 1992-01-22
MX18633A (es) 1993-11-01
HU206360B (en) 1992-10-28
ES2095843T3 (es) 1997-03-01
IL92623A0 (en) 1990-08-31
DE68927636T2 (de) 1997-05-28
EP0387448B1 (de) 1997-01-08
IL92623A (en) 1994-07-31
ATE147389T1 (de) 1997-01-15
HU896486D0 (en) 1990-02-28
CA2005166A1 (en) 1990-09-15
KR900014402A (ko) 1990-10-23
GR3022830T3 (en) 1997-06-30
JPH02268188A (ja) 1990-11-01
EP0387448A2 (de) 1990-09-19
US4888100A (en) 1989-12-19
HUT53647A (en) 1990-11-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee