DE68923625D1 - Enzymatischer Prozess zur Herstellung immunomodulatorischer Pentapeptide und Intermediate zu deren Herstellung. - Google Patents

Enzymatischer Prozess zur Herstellung immunomodulatorischer Pentapeptide und Intermediate zu deren Herstellung.

Info

Publication number
DE68923625D1
DE68923625D1 DE68923625T DE68923625T DE68923625D1 DE 68923625 D1 DE68923625 D1 DE 68923625D1 DE 68923625 T DE68923625 T DE 68923625T DE 68923625 T DE68923625 T DE 68923625T DE 68923625 D1 DE68923625 D1 DE 68923625D1
Authority
DE
Germany
Prior art keywords
amino acid
acid residue
amino
omega
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68923625T
Other languages
English (en)
Other versions
DE68923625T2 (de
Inventor
Stig Aasmul-Olsen
Anders J Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
CARLBIOTECH Ltd KOPENHAGEN DK AS
CARLBIOTECH Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CARLBIOTECH Ltd KOPENHAGEN DK AS, CARLBIOTECH Ltd AS filed Critical CARLBIOTECH Ltd KOPENHAGEN DK AS
Application granted granted Critical
Publication of DE68923625D1 publication Critical patent/DE68923625D1/de
Publication of DE68923625T2 publication Critical patent/DE68923625T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/66Thymopoietins
    • C07K14/662Thymopoietins at least 1 amino acid in D-form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE68923625T 1988-01-14 1989-01-16 Enzymatischer Prozess zur Herstellung immunomodulatorischer Pentapeptide und Intermediate zu deren Herstellung. Expired - Lifetime DE68923625T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK015888A DK15888D0 (da) 1988-01-14 1988-01-14 Enzymatisk fremgangsmaade til fremstilling af immunmodulerende pentapeptider samt mellemprodukter til brug ved fremgangsmaaden

Publications (2)

Publication Number Publication Date
DE68923625D1 true DE68923625D1 (de) 1995-09-07
DE68923625T2 DE68923625T2 (de) 1996-03-28

Family

ID=8090415

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68923625T Expired - Lifetime DE68923625T2 (de) 1988-01-14 1989-01-16 Enzymatischer Prozess zur Herstellung immunomodulatorischer Pentapeptide und Intermediate zu deren Herstellung.

Country Status (9)

Country Link
EP (1) EP0324659B1 (de)
AT (1) ATE125819T1 (de)
AU (1) AU2943989A (de)
DE (1) DE68923625T2 (de)
DK (2) DK15888D0 (de)
ES (1) ES2079374T3 (de)
HU (1) HUT57794A (de)
IT (1) IT1223774B (de)
WO (1) WO1989006656A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461834B1 (en) 1998-11-06 2002-10-08 Bionebraska, Inc. Clostripain catalyzed amidation of peptides
EP1625515B1 (de) * 2003-05-17 2018-09-05 Zhigu Holdings Limited System und verfahren zur bereitstellung von mehrfachwiedergaben eines dokumentinhalts
JP2010539024A (ja) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト ガストリン−1およびG−Pen−GRGDSPCAの治療学的な使用
WO2009039970A1 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of bpp-b as a therapeutic agent
RU2010114022A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Сочетание спленопентина и тимопентина и их применение в лекарственном средстве
JP6348283B2 (ja) 2011-01-27 2018-06-27 ニューレン ファーマシューティカルズ リミテッド グリシル−l−2−メチルプロリル−l−グルタミン酸を用いる自閉症スペクトラム障害の治療

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1184770C2 (de) * 1961-06-01 1965-09-02 Hoffmann La Roche Verfahren zur Herstellung von antibacteriell wirksamen Peptiden
FI40902B (de) * 1962-10-12 1969-03-31 Hoffmann La Roche
JPS5443076B2 (de) * 1974-04-24 1979-12-18
FR2294715A1 (fr) * 1974-12-17 1976-07-16 Inst Rech Scient Nouveau peptide utilisable en therapeutique et son procede d'obtention
WO1980002157A1 (en) * 1979-04-06 1980-10-16 Forenede Bryggerier As A process for enzymatic production of peptides
US4361673A (en) * 1980-09-19 1982-11-30 American Home Products Corporation Polypeptide compositions
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
JPS5917997A (ja) * 1982-07-23 1984-01-30 Toyo Soda Mfg Co Ltd ジペプチドエステルとアミノ酸エステルとの付加化合物の製造方法
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
DE3619633A1 (de) * 1986-06-11 1987-12-17 Hoechst Ag Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
EP0288965A2 (de) * 1987-04-29 1988-11-02 Hoechst Aktiengesellschaft Peptide mit Phospholipase A2- hemmender Wirkung

Also Published As

Publication number Publication date
IT1223774B (it) 1990-09-29
DK15888D0 (da) 1988-01-14
EP0324659A2 (de) 1989-07-19
ATE125819T1 (de) 1995-08-15
WO1989006656A1 (en) 1989-07-27
EP0324659A3 (de) 1991-04-03
DK169090A (da) 1990-09-14
EP0324659B1 (de) 1995-08-02
IT8867761A0 (it) 1988-08-12
DK169090D0 (da) 1990-07-13
ES2079374T3 (es) 1996-01-16
DE68923625T2 (de) 1996-03-28
HU890937D0 (en) 1991-11-28
AU2943989A (en) 1989-08-11
HUT57794A (en) 1991-12-30

Similar Documents

Publication Publication Date Title
EP0017485B1 (de) Verfahren zur enzymatischen Herstellung von Peptiden
WO1995020039B1 (en) Customized proteases with altered transacylation activity
HUT54213A (en) Process for the enzymatic removal of n-terminal sequence of proteins
US4086136A (en) Process for producing a peptide using a serine or thiol proteinase
AU8600491A (en) A novel protease
DE68923625T2 (de) Enzymatischer Prozess zur Herstellung immunomodulatorischer Pentapeptide und Intermediate zu deren Herstellung.
Shui-Tein et al. Stable industrial protease catalyzed peptide bond formation in organic solvent.
AU589289B2 (en) Novel inhibitor peptides
WO1999002708A8 (en) Fusion proteins comprising sequences derived from bovine if1 atpase inhibitor protein
CA1059938A (en) Process for producing a peptide
Gittel et al. Directed N-terminal elongation of unprotected peptides catalyzed by cathepsin C in water
Shibata et al. A novel type of substrate specificity of rice BAPAase (benzoyl-L-arginine p-nitroanilide hydrolase) with mixed endopeptidase and carboxypeptidase
DE3887854D1 (de) Verfahren zur Herstellung von Dipeptiden.
EP0945512A3 (de) Serinproteasen
Rolland-Fulcrandr et al. The use of a glutamic acid specific endopeptidase in peptide synthesis
NO157706B (no) Fremgangsmÿte for enzymatisk fremstilling av peptider.
IT1214410B (it) Metodo di ottenimento di n-formil-l-peptidi

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ORTHO PHARMACEUTICAL CORP., RARITAN, N.J., US