DE68910867D1 - Matrix für die transdermale Abgabe von Arzneimitteln. - Google Patents

Matrix für die transdermale Abgabe von Arzneimitteln.

Info

Publication number
DE68910867D1
DE68910867D1 DE89303914T DE68910867T DE68910867D1 DE 68910867 D1 DE68910867 D1 DE 68910867D1 DE 89303914 T DE89303914 T DE 89303914T DE 68910867 T DE68910867 T DE 68910867T DE 68910867 D1 DE68910867 D1 DE 68910867D1
Authority
DE
Germany
Prior art keywords
drugs
matrix
transdermal delivery
transdermal
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89303914T
Other languages
English (en)
Other versions
DE68910867T2 (de
Inventor
Randall Paul Sweet
Chi-Long Lee
Gerald Alphonse Gornowicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Silicones Corp
Original Assignee
Dow Corning Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Corning Corp filed Critical Dow Corning Corp
Application granted granted Critical
Publication of DE68910867D1 publication Critical patent/DE68910867D1/de
Publication of DE68910867T2 publication Critical patent/DE68910867T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/61—Polysiloxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polyurethanes Or Polyureas (AREA)
DE68910867T 1988-04-22 1989-04-20 Matrix für die transdermale Abgabe von Arzneimitteln. Expired - Fee Related DE68910867T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/184,748 US4840796A (en) 1988-04-22 1988-04-22 Block copolymer matrix for transdermal drug release

Publications (2)

Publication Number Publication Date
DE68910867D1 true DE68910867D1 (de) 1994-01-05
DE68910867T2 DE68910867T2 (de) 1994-05-26

Family

ID=22678177

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68910867T Expired - Fee Related DE68910867T2 (de) 1988-04-22 1989-04-20 Matrix für die transdermale Abgabe von Arzneimitteln.

Country Status (5)

Country Link
US (1) US4840796A (de)
EP (1) EP0338819B1 (de)
JP (1) JPH0725668B2 (de)
CA (1) CA1323473C (de)
DE (1) DE68910867T2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
DE3743946A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
US5306502A (en) * 1987-09-01 1994-04-26 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for delivering nitroglycerin to the skin, processes for the production thereof and the use thereof
US5273757A (en) * 1987-09-01 1993-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for the delivery of substances, processes for the production thereof and use thereof
US5019395A (en) * 1988-03-08 1991-05-28 Warner-Lambert Company Compositions with enhanced penetration
US4951657A (en) * 1988-04-22 1990-08-28 Dow Corning Corporation Heat sealable membrane for transdermal drug release
GB8811776D0 (en) * 1988-05-18 1988-06-22 Smith & Nephew Ass Dressings
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
CA2060113A1 (en) * 1991-02-01 1992-08-02 Agis Kydonieus Temperature activated controlled release device
US5580573A (en) * 1991-02-01 1996-12-03 E. R. Squibb And Sons, Inc. Temperature activated controlled release
US6010715A (en) * 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
CA2075517C (en) * 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
EP0799017A1 (de) * 1994-11-15 1997-10-08 Osmotics Corporation Hautpflegezusammensetzungen und verfahren
US5756572A (en) * 1995-07-24 1998-05-26 Dow Corning Corporation Silicone pressure sensitive adhesive composition containing thermoplastic multi-segmented copolymer
AU1800099A (en) * 1997-11-25 1999-06-15 Theratech, Inc. Transdermal delivery devices containing polydiorganosiloxane polymers to regulate adhesive properties
PT1140039E (pt) 1998-12-18 2010-02-03 Alza Corp Dispositivos transparentes de administração transdérmica de nicotina
EP1169025B1 (de) * 1999-04-01 2005-08-24 Alza Corporation Transdermale vorrichtung zur arzneistoffverabreichung mit einem polyurethanwirkstoffreservoir
US20020004065A1 (en) 2000-01-20 2002-01-10 David Kanios Compositions and methods to effect the release profile in the transdermal administration of active agents
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
EP1742620B1 (de) 2004-03-12 2012-12-05 Dow Corning Corporation Verfahren zur herstellung von silikon-kontaktklebern zur abgabe von hydrophilen arzneimitteln unter verwendung eines silikonpolyethers
US20050220835A1 (en) 2004-03-30 2005-10-06 Jayaraman Ramesh B Agent eluting bioimplantable devices and polymer systems for their preparation
KR20080072834A (ko) * 2005-11-04 2008-08-07 다우 코닝 코포레이션 광전지의 캡슐화
TW201005975A (en) * 2008-03-14 2010-02-01 Dow Corning Method of forming a photovoltaic cell module
CN102931259A (zh) 2008-10-31 2013-02-13 陶氏康宁公司 光生伏打电池组件和形成方法
US20110129676A1 (en) * 2009-12-01 2011-06-02 Bravet David J Multi-layered front sheet encapsulant for photovoltaic modules
US9006163B2 (en) 2011-12-15 2015-04-14 Colgate-Palmolive Company Cleansing compositions with polyurethane-34
ES2957540T3 (es) * 2012-07-10 2024-01-22 Massachusetts Gen Hospital Sistema y método para monitorizar y tratar una superficie de un sujeto
EP3515961A1 (de) 2016-09-19 2019-07-31 Dow Silicones Corporation Polyurethan-polyorganosiloxan-copolymer und verfahren zu dessen herstellung
JP6840228B2 (ja) 2016-09-19 2021-03-10 ダウ シリコーンズ コーポレーション 皮膚接触接着剤並びにその調製方法及び使用
EP3522986A1 (de) * 2016-09-19 2019-08-14 Dow France S.A.S. Copolymerzusammensetzung zur körperpflege
WO2018052648A1 (en) 2016-09-19 2018-03-22 Dow Corning Corporation Copolymer composition for personal care
CN109843380B (zh) * 2016-09-19 2021-08-17 美国陶氏有机硅公司 用于涂层和粘合剂应用的共聚物组合物
US20210177726A1 (en) 2017-02-15 2021-06-17 Dow Silicones Corporation Personal care compositions including a polyurethane - polyorganosiloxane copolymer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
CA1206668A (en) * 1980-02-29 1986-06-24 Robert S. Ward, Jr. Polymer surfaces for blood-contacting surfaces of a biomedical device, and methods for forming
US4336243A (en) * 1980-08-11 1982-06-22 G. D. Searle & Co. Transdermal nitroglycerin pad
US4435180A (en) * 1982-05-25 1984-03-06 Alza Corporation Elastomeric active agent delivery system and method of use
JPS5984817A (ja) * 1982-11-08 1984-05-16 Sekisui Chem Co Ltd 薬剤徐放性製剤
US4559054A (en) * 1984-08-09 1985-12-17 Research Corporation Rate-controlled drug release system
US4638043A (en) * 1984-11-13 1987-01-20 Thermedics, Inc. Drug release system
EP0196769B1 (de) * 1985-02-25 1992-07-08 Rutgers, The State University of New Jersey Dosierungssystem für transdermale Absorption von Arzneimittelwirkstoffen
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
US4631329A (en) * 1985-11-29 1986-12-23 Dow Corning Corporation Moisture resistant polyurethanes derived from non-aromatic diisocyanates

Also Published As

Publication number Publication date
CA1323473C (en) 1993-10-26
JPH0725668B2 (ja) 1995-03-22
DE68910867T2 (de) 1994-05-26
EP0338819A3 (en) 1990-02-21
US4840796A (en) 1989-06-20
JPH01311016A (ja) 1989-12-15
EP0338819A2 (de) 1989-10-25
EP0338819B1 (de) 1993-11-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee