DE68906309T2 - Methode zur Behandlung von Kachexie und bestimmte dafür anzuwendende Verbindungen. - Google Patents

Methode zur Behandlung von Kachexie und bestimmte dafür anzuwendende Verbindungen.

Info

Publication number
DE68906309T2
DE68906309T2 DE89306147T DE68906309T DE68906309T2 DE 68906309 T2 DE68906309 T2 DE 68906309T2 DE 89306147 T DE89306147 T DE 89306147T DE 68906309 T DE68906309 T DE 68906309T DE 68906309 T2 DE68906309 T2 DE 68906309T2
Authority
DE
Germany
Prior art keywords
hydrogen
alkyl
halogen
certain compounds
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89306147T
Other languages
English (en)
Other versions
DE68906309D1 (de
Inventor
Yo Takiguchi
Jun Ohsumi
Yasuo Shimoji
Kazuhiko Sasagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE68906309D1 publication Critical patent/DE68906309D1/de
Application granted granted Critical
Publication of DE68906309T2 publication Critical patent/DE68906309T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Storage Of Fruits Or Vegetables (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE89306147T 1988-06-16 1989-06-16 Methode zur Behandlung von Kachexie und bestimmte dafür anzuwendende Verbindungen. Expired - Fee Related DE68906309T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14913788 1988-06-16

Publications (2)

Publication Number Publication Date
DE68906309D1 DE68906309D1 (de) 1993-06-09
DE68906309T2 true DE68906309T2 (de) 1994-01-05

Family

ID=15468558

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68922408T Expired - Lifetime DE68922408D1 (de) 1988-06-16 1989-06-16 Neue Triazolopyrimidin- und Pyrazolopyrimidinderivate zur Behandlung von Kachexie.
DE89306147T Expired - Fee Related DE68906309T2 (de) 1988-06-16 1989-06-16 Methode zur Behandlung von Kachexie und bestimmte dafür anzuwendende Verbindungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE68922408T Expired - Lifetime DE68922408D1 (de) 1988-06-16 1989-06-16 Neue Triazolopyrimidin- und Pyrazolopyrimidinderivate zur Behandlung von Kachexie.

Country Status (9)

Country Link
US (2) US5055479A (de)
EP (2) EP0347252B1 (de)
JP (1) JPH0276880A (de)
KR (1) KR910000737A (de)
AT (2) ATE121744T1 (de)
CA (1) CA1329199C (de)
DE (2) DE68922408D1 (de)
ES (1) ES2057126T3 (de)
IE (2) IE62915B1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
US5264220A (en) * 1991-11-12 1993-11-23 Long David M Jr Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
JPH10218881A (ja) * 1997-02-03 1998-08-18 Pola Chem Ind Inc 新規なピロロピラゾロピリミジン誘導体
TWI271406B (en) * 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
US20020061897A1 (en) 2000-03-30 2002-05-23 Elliott Richard L. Neuropeptide Y antagonists
JP2002043785A (ja) 2000-07-28 2002-02-08 Murata Mfg Co Ltd シールドケース及びそれを用いた電子機器及びそれを用いた電子装置及びシールドケースの製造方法
DZ3415A1 (fr) 2000-08-31 2002-03-07 Chiron Corp Guanidinobenzamides comme mc4-r agonistes.
JP4172541B2 (ja) 2001-04-09 2008-10-29 ノバルティス バクシンズ アンド ダイアグノスティックス， インコーポレーテッド グアニジノ化合物
US7425559B2 (en) 2001-07-13 2008-09-16 Btg International Limited Medicine containing pyrimidine derivative
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
US20050124652A1 (en) * 2002-02-04 2005-06-09 Rustum Boyce Guanidino compounds
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
AU2003219914A1 (en) * 2002-02-25 2003-09-09 Chiron Corporation Intranasal administration of mc4-r agonists
AU2003245325A1 (en) * 2002-05-23 2003-12-12 Chiron Corporation Substituted quinazolinone compounds
US7051505B2 (en) * 2002-08-21 2006-05-30 Greg Brannstrom Tomato harvester
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) * 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
KR20060018217A (ko) * 2003-05-23 2006-02-28 카이론 코포레이션 Ｍｃ4-ｒ 작용제로서 구아니디노-치환된 퀴나졸리논 화합물
US20050009919A1 (en) * 2003-07-07 2005-01-13 Clouatre Dallas L. Treating cachexia and excessive catabolism with (-)-hydroxycitric acid
MXPA06005736A (es) * 2003-11-19 2006-12-14 Chiron Corp Compuestos de quinazolinona con bioacumulacion reducida.
WO2009120836A1 (en) * 2008-03-26 2009-10-01 Neurosigma, Inc. Methods for identifying and targeting autonomic brain regions
MY152687A (en) 2008-04-15 2014-10-31 Eisai R&D Man Co Ltd 3-phenylpyrazolo[5,1-b]thiazole compound
GB0917774D0 (en) * 2009-10-09 2009-11-25 Senexis Ltd Novel pharmaceutical compounds
GB0917775D0 (en) 2009-10-09 2009-11-25 Btg Int Ltd Novel pharmaceutical compounds
WO2012027239A1 (en) * 2010-08-23 2012-03-01 Schering Corporation NOVEL PYRAZOLO[1,5-a]PYRROLO[3,2-e]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
KR20160101398A (ko) 2015-02-17 2016-08-25 순천대학교 산학협력단 바륨타이타네이트층을 포함하는 복합 세라믹 전극의 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51141896A (en) * 1975-05-31 1976-12-07 Sankyo Co Ltd Process for preparing fused ring triazoropyrimidine derivatives
DE2704030A1 (de) * 1976-02-12 1977-08-18 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
JPS5353697A (en) * 1976-10-20 1978-05-16 Sankyo Co Ltd Tricyclic triazolopyrimidine derivatives
US4619933A (en) * 1979-09-28 1986-10-28 The Upjohn Company 6-aryl pyrimidines for treating aplastic anemia
JPS5735593A (en) * 1980-08-12 1982-02-26 Mochida Pharmaceut Co Ltd Novel pyrolo 3,2-e -s-triazolo 1,5-a pyrimidine derivative
DE3241827T1 (de) * 1982-02-19 1984-01-12 Mochida Pharmaceutical Co., Ltd., Tokyo Neue s-Triazolo[1,5-a]pyrimidin-Derivate
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same

Also Published As

Publication number Publication date
DE68922408D1 (de) 1995-06-01
EP0347252A3 (de) 1991-03-27
IE930392L (en) 1989-12-16
ATE121744T1 (de) 1995-05-15
DE68906309D1 (de) 1993-06-09
ES2057126T3 (es) 1994-10-16
KR910000737A (ko) 1991-01-30
US5055479A (en) 1991-10-08
EP0347252B1 (de) 1993-05-05
IE891963L (en) 1989-12-16
EP0508549A3 (de) 1992-11-25
US5086057A (en) 1992-02-04
EP0347252A2 (de) 1989-12-20
EP0508549A2 (de) 1992-10-14
EP0508549B1 (de) 1995-04-26
CA1329199C (en) 1994-05-03
IE62915B1 (en) 1995-03-08
ATE88894T1 (de) 1993-05-15
JPH0276880A (ja) 1990-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee