DE68906132T2 - Flecainidacetat enthaltende Arzneizubereitung mit verzögerter Wirkstofffreigabe. - Google Patents

Flecainidacetat enthaltende Arzneizubereitung mit verzögerter Wirkstofffreigabe.

Info

Publication number
DE68906132T2
DE68906132T2 DE89312107T DE68906132T DE68906132T2 DE 68906132 T2 DE68906132 T2 DE 68906132T2 DE 89312107 T DE89312107 T DE 89312107T DE 68906132 T DE68906132 T DE 68906132T DE 68906132 T2 DE68906132 T2 DE 68906132T2
Authority
DE
Germany
Prior art keywords
active ingredient
pharmaceutical preparation
delayed release
preparation containing
flecainide acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89312107T
Other languages
English (en)
Other versions
DE68906132D1 (de
Inventor
David Porter
Andrew M Twitchell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda AB
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of DE68906132D1 publication Critical patent/DE68906132D1/de
Application granted granted Critical
Publication of DE68906132T2 publication Critical patent/DE68906132T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
DE89312107T 1988-11-30 1989-11-22 Flecainidacetat enthaltende Arzneizubereitung mit verzögerter Wirkstofffreigabe. Expired - Lifetime DE68906132T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/277,899 US4938966A (en) 1988-11-30 1988-11-30 Controlled release flecainide acetate formulation

Publications (2)

Publication Number Publication Date
DE68906132D1 DE68906132D1 (de) 1993-05-27
DE68906132T2 true DE68906132T2 (de) 1993-10-14

Family

ID=23062855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89312107T Expired - Lifetime DE68906132T2 (de) 1988-11-30 1989-11-22 Flecainidacetat enthaltende Arzneizubereitung mit verzögerter Wirkstofffreigabe.

Country Status (10)

Country Link
US (1) US4938966A (de)
EP (1) EP0371683B1 (de)
JP (1) JP3004663B2 (de)
AU (1) AU619917B2 (de)
CA (1) CA2002337C (de)
CS (1) CS390791A3 (de)
DE (1) DE68906132T2 (de)
ES (1) ES2054029T3 (de)
HK (1) HK1004887A1 (de)
NZ (1) NZ231308A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0010446D0 (en) * 2000-04-28 2000-06-14 Glaxo Wellcome Kk Pharmaceutical formulation
EP2359814A1 (de) 2010-02-11 2011-08-24 Laboratorios Liconsa, S.A. Pharmazeutische Minitabletten zur verzögerten Freisetzung von Flecainidacetat
EP2861254B1 (de) * 2012-06-13 2020-04-29 Acesion Pharma ApS Pharmazeutische zusammensetzungen für eine kombinationstherapie
WO2020236631A1 (en) * 2019-05-17 2020-11-26 Alsar Ltd Partnership Flecainide combination and controlled-release formulations for treating heart diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005209A (en) * 1974-04-01 1977-01-25 Riker Laboratories, Inc. Antiarrhythmic method utilizing fluoroalkoxy-N-piperidyl and pyridyl benzamides
US3900481A (en) * 1974-04-01 1975-08-19 Riker Laboratories Inc Derivatives of pyrrolidine and piperidine
US3987201A (en) * 1974-12-24 1976-10-19 Eli Lilly And Company Method for treating arrhythmia
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
US4604394A (en) * 1984-10-01 1986-08-05 Merck & Co., Inc. Antiarrhythmic compositions and method
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
JPS63267720A (ja) * 1987-04-24 1988-11-04 Morishita Seiyaku Kk エモルフアゾンの徐放性製剤

Also Published As

Publication number Publication date
AU4551589A (en) 1990-06-07
US4938966A (en) 1990-07-03
CA2002337A1 (en) 1990-05-31
JPH02193923A (ja) 1990-07-31
EP0371683B1 (de) 1993-04-21
CA2002337C (en) 2000-07-04
HK1004887A1 (en) 1998-12-11
DE68906132D1 (de) 1993-05-27
ES2054029T3 (es) 1994-08-01
JP3004663B2 (ja) 2000-01-31
NZ231308A (en) 1991-10-25
CS390791A3 (en) 1992-06-17
EP0371683A1 (de) 1990-06-06
AU619917B2 (en) 1992-02-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MEDA AB, SOLNA, SE