DE68904586D1 - Histamin-derivat, verfahren zu dessen herstellung und therapeutischen anwendung. - Google Patents

Histamin-derivat, verfahren zu dessen herstellung und therapeutischen anwendung.

Info

Publication number
DE68904586D1
DE68904586D1 DE8989401143T DE68904586T DE68904586D1 DE 68904586 D1 DE68904586 D1 DE 68904586D1 DE 8989401143 T DE8989401143 T DE 8989401143T DE 68904586 T DE68904586 T DE 68904586T DE 68904586 D1 DE68904586 D1 DE 68904586D1
Authority
DE
Germany
Prior art keywords
production
therapeutic use
histamine derivative
alkyl
histamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989401143T
Other languages
English (en)
Other versions
DE68904586T2 (de
Inventor
Jean-Michel Res Du Chat Arrang
Monique Garbarg
Walter Schunack
Jean-Charles Schwartz
Ralph Ortwin Lipp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioprojet SC
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Bioprojet SC
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet SC, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Bioprojet SC
Publication of DE68904586D1 publication Critical patent/DE68904586D1/de
Application granted granted Critical
Publication of DE68904586T2 publication Critical patent/DE68904586T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE8989401143T 1988-04-22 1989-04-21 Histamin-derivat, verfahren zu dessen herstellung und therapeutischen anwendung. Expired - Lifetime DE68904586T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8805399A FR2630328B1 (fr) 1988-04-22 1988-04-22 Derive de l'histamine, sa preparation et son application en therapeutique

Publications (2)

Publication Number Publication Date
DE68904586D1 true DE68904586D1 (de) 1993-03-11
DE68904586T2 DE68904586T2 (de) 1993-08-19

Family

ID=9365603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989401143T Expired - Lifetime DE68904586T2 (de) 1988-04-22 1989-04-21 Histamin-derivat, verfahren zu dessen herstellung und therapeutischen anwendung.

Country Status (7)

Country Link
US (1) US5034539A (de)
EP (1) EP0338939B1 (de)
JP (1) JPH0655728B2 (de)
AT (1) ATE85051T1 (de)
DE (1) DE68904586T2 (de)
ES (1) ES2046500T3 (de)
FR (1) FR2630328B1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661909B1 (fr) * 1990-05-09 1997-08-14 Inst Nat Sante Rech Med Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.
NZ238688A (en) * 1990-06-28 1992-05-26 Smithkline Beecham Corp Substituted histidines: pharmaceutical compositions, preparation and uses thereof
US5162541A (en) * 1990-09-10 1992-11-10 Schering Corporation Transfer hydrogenolysis of alkylheteroaryl halo-containing compounds
US5463074A (en) * 1991-12-18 1995-10-31 Schering Corporation Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring
ATE128708T1 (de) * 1991-12-18 1995-10-15 Schering Corp Imidazolylalkyl- piperazin und -diazepin derivate als histamin h3 agonisten/antagonisten.
US5932596A (en) * 1991-12-18 1999-08-03 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring
US5807872A (en) * 1992-12-16 1998-09-15 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
AU3944593A (en) * 1992-04-01 1993-11-08 University Of Toledo, The 4-(4'-piperidinyl or 3'-pirrolidinyl) substituted imidazoles as H3-receptor antagonists and therapeutic uses thereof
US5639775A (en) * 1992-04-01 1997-06-17 The University Of Toledo 4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H3 -receptor antagonists and therapeutic uses thereof
US5486526A (en) * 1992-04-01 1996-01-23 The University Of Toledo Histamine H3 -receptor antagonists and therapeutic uses thereof
US5648355A (en) * 1994-02-09 1997-07-15 Kos Pharmaceutical, Inc. Method of treatment of endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin
US5905152A (en) * 1996-08-08 1999-05-18 Schering Corporation Preparation of aminomethyl-phenylimidazoles
EP1147092A1 (de) 1999-01-18 2001-10-24 Novo Nordisk A/S Substituierte imidazole, ihre herstellung und verwendung
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6610721B2 (en) 2000-03-17 2003-08-26 Novo Nordisk A/S Imidazo heterocyclic compounds
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
JP3892894B2 (ja) * 2005-04-28 2007-03-14 大塚製薬株式会社 カルボスチリル化合物の製造法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2586562B1 (fr) * 1985-09-02 1989-03-10 Inst Nat Sante Rech Med Composition pharmaceutique contenant de l'a-methylhistamine

Also Published As

Publication number Publication date
ES2046500T3 (es) 1994-02-01
FR2630328B1 (fr) 1990-08-24
FR2630328A1 (fr) 1989-10-27
EP0338939A1 (de) 1989-10-25
JPH0655728B2 (ja) 1994-07-27
EP0338939B1 (de) 1993-01-27
DE68904586T2 (de) 1993-08-19
JPH037264A (ja) 1991-01-14
ATE85051T1 (de) 1993-02-15
US5034539A (en) 1991-07-23

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