DE615481C - Process for the preparation of long-lasting lecithin emulsions for therapeutic purposes - Google Patents
Process for the preparation of long-lasting lecithin emulsions for therapeutic purposesInfo
- Publication number
- DE615481C DE615481C DEA72442D DEA0072442D DE615481C DE 615481 C DE615481 C DE 615481C DE A72442 D DEA72442 D DE A72442D DE A0072442 D DEA0072442 D DE A0072442D DE 615481 C DE615481 C DE 615481C
- Authority
- DE
- Germany
- Prior art keywords
- oil
- lecithin
- water
- parts
- therapeutic purposes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Plant Substances (AREA)
Description
Verfahren zur Herstellung haltbarer Lecithinemulsionen für therapeutische Zwecke Die Eigenschaft des Lecithins pflanzlichen und tierischen Ursprungs, in Wasser aufzuquellen und hiermit dauerhafte Emulsionen zu bilden, ist bekannt. Dagegen gelingt es nicht; derartige haltbare Emulsionen herzustellen, wenn man zu der Mischung von Lecithin und Wasser fettes Öl und Paraffinöl oder einen dieser beiden Stoffe gibt.Process for the preparation of durable lecithin emulsions for therapeutic use Purposes The property of the lecithin of vegetable and animal origin, in water It is known to swell and thereby form permanent emulsions. On the other hand succeeds it not; to produce such durable emulsions when adding to the mixture of Lecithin and water are fatty oil and paraffin oil or one of these two substances.
Wie nun gefunden wurde, kann man solche Emulsionen, die neben Lecithin pflanzlichen oder tierischen Ursprungs Wasser, fettes Öl und gegebenenfalls Paraffmäl enthalten, von außerordentlich großer Haltbarkeit gewinnen, wenn man Pineöl oder Mischungen von Pineöl und anderen Terpenverbindungen zusetzt.As has now been found, such emulsions can be used in addition to lecithin of vegetable or animal origin water, fatty oil and, if necessary, paraffin contain, of extraordinarily great durability, if you use pine oil or Adds mixtures of pine oil and other terpene compounds.
Derartige haltbare und sich nicht entmischende Lecithin, Pineöl, fettes Öl und Paraffinöl enthaltende wässerige Emulsionen sind für therapeutische Zwecke sehr geeignet, insbesondere zum Schutze der Haut gegen Sonnenbrand unter gleichzeitiger Erzielung einer gesunden Bräunung und zum Einreiben gegen rheumatische Erkrankungen.Such durable and non-segregating lecithin, pine oil, fatty Aqueous emulsions containing oil and paraffin oil are for therapeutic purposes very suitable, especially for protecting the skin against sunburn while at the same time Achieving a healthy tan and for rubbing against rheumatic diseases.
Die Emulsion wirkt auf die Fett- und Schmutzteile der Haut lösend ein. Die Terpenverbindungenerzeugen eine stärkere Durchblutung der eingeriebenen Hautpartien, während das Lecithin von der Haut resorbiert wird. Die Zusätze von fettem Öl und Paraffinöl wirken als vorzügliche Gleitmittel beim Massieren.The emulsion has a dissolving effect on the fat and dirt parts of the skin a. The terpene compounds create a stronger blood flow to the rubbed Areas of the skin while the lecithin is absorbed by the skin. The additions of Fatty oil and paraffin oil act as excellent lubricants when massaging.
Bei der Herstellung der Emulsion ist man jedoch nicht darauf angewiesen, von dem verhältnismäßig kostspieligen reinen Lecithin auszugehen. Es besteht vielmehr die Möglichkeit, eine wasser- und ölhaltige Pflanzenlecithinemulsion, wie sie z. B. in sehr großen Mengen als Nebenprodukt bei der Extraktion von Sojaöl aus Sojabohnen gewonnen wird, in frischem Zustande für diesen Zweck zu benutzen.When making the emulsion, however, one does not have to rely on start from the relatively expensive pure lecithin. Rather, it exists the possibility of a water- and oil-containing vegetable lecithin emulsion, as z. B. in very large quantities as a by-product in the extraction of soybean oil from soybeans is obtained to use fresh for this purpose.
Bei der Extraktion der Sojabohnen, beispielsweise mit Benzin, werden gleichzeitig erhebliche Mengen des in den Bohnen vorhandenen Lecithins ausgelöst. Das Lecithin ist zunächst in dem Öl kolloidal gelöst, scheidet sich hieraus bei längerem Stehen aus und setzt sich zu Boden. Da jedoch- diese Selbstausscheidung sehr lange Zeit in Anspruch nimmt und auf diese Weise nur ein bereits verdorbenes, sehr minderwertiges Lecithin gewonnen werden kann, wird die Ausscheidung zweckmäßig durch Einleiten von entspanntem- Wasserdampf in das 01-beschleunigt. Das Lecithin quillt mit dem in dem Ö] zu Wasser kondensierten Dampf auf, setzt sich zu Boden und wird hier als Lecithin-Öl-Wasser-Gemisch, das man gewöhnlich als Sojaschlamm bezeichnet, abgetrennt. Durch Zentrifugieren läßt sich die Hauptmenge des Öles entfernen, so daß nunmehr eine Emulsion erhalten wird, die z. B. aus 3 5 Teiler Lecithin, 15 Teilen Öl und 5o Teilen Wasser zusammengesetzt ist.When extracting the soybeans, for example with gasoline at the same time triggered considerable amounts of the lecithin present in the beans. The lecithin is initially colloidally dissolved in the oil, from which it separates prolonged standing and sits on the ground. But there- this self-elimination takes a very long time and in this way only a spoiled, If very inferior lecithin can be obtained, excretion becomes expedient by introducing relaxed steam into the 01 accelerated. The lecithin swells up with the steam condensed into water in the oil, and sits on the floor and is used here as a lecithin-oil-water mixture, which is usually called soy sludge designated, separated. Most of the oil can be removed by centrifugation, so that now an emulsion is obtained which, for. B. from 3 5 parts lecithin, 15 Parts of oil and 50 parts of water.
Um eine Zersetzung dieser Emulsion durch Gärung zu vermeiden, wurde das Wasser aus dem frischen Sojaschlamm seither sofort unter Vakuum verdampft, so daß eine haltbare Mischung aus z. B. 7o Teilen Lecithin und 3o Teilren Öl gewonnen wird. Dieses Lecithin-Öl-Gemisch kann für die Ausführung der Erfindung Verwendung finden. Außerdem hat sie aber den großen Vorteil, daß man für den gleichen Zweck den frischen wasserhaltigen Sojaschlamm benutzen kann, indem man diesen z. B. mit- einem - Gemisch von Pineöl, Terpentinöl gegeb.ernenfalls unter Zusatz von Paraffinöl und weiteren Mengen Wasser und fettem Öl durch kräftiges Rühren und Schütteln m einer geeigneten Vorrichtung emulgiert. Es gelingt also auf diese Weise,. den sonst leicht verderblichen Sojaschlamm sofort in eine haltbare Emulsion üherzuführen.In order to avoid a decomposition of this emulsion by fermentation, was the water from the fresh soy mud since then immediately under vacuum evaporated, so that a durable mixture of z. B. 7o parts of lecithin and 3o parts Oil is obtained. This lecithin-oil mixture can be used to carry out the invention Find use. But it also has the great advantage that you can buy for the same Purpose can use the fresh water-containing soy mud by z. B. with a mixture of pine oil, turpentine oil, otherwise with the addition of Paraffin oil and additional amounts of water and fatty oil by stirring and shaking vigorously emulsified in a suitable device. So it succeeds in this way. the Convert otherwise easily perishable soy sludge immediately into a long-lasting emulsion.
Zur Ausführung der Erfindung werden beispielsweise 8 Teile Sojalecithin mit einem Ölgehalt von 30 0,lo, die durch -Trocknexi voli frischem Sojaschlamm,. gewonnen worden sind, mit 15 Teilen Pineöl, 12 Teilen Terpentinöl, io Teilen Paraffinöl und _S5 Teilen. Wasser durch kräftiges Rühren emulgiert. Ferner kann man z. B. so verfahren, daß 16 Teile frischer Sojaschlamm mit einem Gehalt von 35 % Lecithin, 15 % Öl, 5o % Wasser mit 15 Teilen Pineöl, 12 Teilen Terpentinöl, io Teilen raffiniertem Sojabohnenöl und 47 Teilen Wasser emulgiert werden.For example, 8 parts of soy lecithin are used to carry out the invention with an oil content of 30 0, lo, which by -Trocknexi voli fresh soy mud ,. have been obtained with 15 parts pine oil, 12 parts turpentine oil, 10 parts paraffin oil and _S5 parts. Water emulsified by vigorous stirring. Furthermore, you can z. B. so process that 16 parts of fresh soy sludge with a content of 35% lecithin, 15% oil, 50% water with 15 parts pine oil, 12 parts turpentine oil, 10 parts refined Soybean oil and 47 parts of water are emulsified.
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEA72442D DE615481C (en) | 1934-02-07 | 1934-02-08 | Process for the preparation of long-lasting lecithin emulsions for therapeutic purposes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE437859X | 1934-02-07 | ||
DEA72442D DE615481C (en) | 1934-02-07 | 1934-02-08 | Process for the preparation of long-lasting lecithin emulsions for therapeutic purposes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE615481C true DE615481C (en) | 1935-07-05 |
Family
ID=25932779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEA72442D Expired DE615481C (en) | 1934-02-07 | 1934-02-08 | Process for the preparation of long-lasting lecithin emulsions for therapeutic purposes |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE615481C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4258063A (en) * | 1978-06-23 | 1981-03-24 | Henkel Corporation | Self-emulsifying cosmetic base |
-
1934
- 1934-02-08 DE DEA72442D patent/DE615481C/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4258063A (en) * | 1978-06-23 | 1981-03-24 | Henkel Corporation | Self-emulsifying cosmetic base |
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