DE60333211D1 - Neue verbindungen und deren verwendung als ppar-modulatoren - Google Patents
Neue verbindungen und deren verwendung als ppar-modulatorenInfo
- Publication number
- DE60333211D1 DE60333211D1 DE60333211T DE60333211T DE60333211D1 DE 60333211 D1 DE60333211 D1 DE 60333211D1 DE 60333211 T DE60333211 T DE 60333211T DE 60333211 T DE60333211 T DE 60333211T DE 60333211 D1 DE60333211 D1 DE 60333211D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- new compounds
- ppar modulators
- compositions
- ppar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Optical Integrated Circuits (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Semiconductor Memories (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200201631 | 2002-10-28 | ||
DKPA200300793 | 2003-05-26 | ||
PCT/DK2003/000722 WO2004037776A2 (en) | 2002-10-28 | 2003-10-27 | Novel compounds and their use as prar-modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60333211D1 true DE60333211D1 (de) | 2010-08-12 |
Family
ID=32178576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60333211T Expired - Lifetime DE60333211D1 (de) | 2002-10-28 | 2003-10-27 | Neue verbindungen und deren verwendung als ppar-modulatoren |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1558572B1 (de) |
JP (1) | JP4708184B2 (de) |
KR (1) | KR20050061562A (de) |
AT (1) | ATE472526T1 (de) |
AU (2) | AU2003273783C1 (de) |
BR (1) | BR0315683A (de) |
CA (1) | CA2503280A1 (de) |
DE (1) | DE60333211D1 (de) |
ES (1) | ES2345882T3 (de) |
MX (1) | MXPA05004402A (de) |
NO (1) | NO20052575L (de) |
PL (1) | PL376718A1 (de) |
RU (1) | RU2349582C2 (de) |
WO (1) | WO2004037776A2 (de) |
ZA (1) | ZA200502814B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7129268B2 (en) * | 2002-10-28 | 2006-10-31 | Novo Nordisk A/S | Peroxisome proliferator activated receptor-active arylene acetic acid derivatives |
ES2378435T3 (es) | 2003-09-19 | 2012-04-12 | Janssen Pharmaceutica N.V. | �?cidos 4-((fenoxialquil)tio)-fenoxiacéticos y análogos |
BRPI0414554A (pt) * | 2003-10-28 | 2006-11-07 | Reddys Lab Ltd Dr | compostos e seus usos em medicina: processo para preparação destes e composições farmacêuticas que os contenham |
US8053598B2 (en) | 2004-05-05 | 2011-11-08 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
WO2005113506A1 (en) * | 2004-05-14 | 2005-12-01 | Irm Llc | Compounds and compositions as ppar modulators |
JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
NZ568488A (en) | 2005-12-22 | 2011-07-29 | High Point Pharmaceuticals Llc | Phenoxy acetic acids as PPAR delta activators |
PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
WO2007141295A1 (en) * | 2006-06-08 | 2007-12-13 | High Point Pharmaceuticals, Llc | Process for preparing phenoxy acetic acid derivatives |
WO2015035171A1 (en) | 2013-09-09 | 2015-03-12 | High Point Pharmaceuticals, Llc | Use of a ppar-delta agonist for treating muscle atrophy |
US20230002344A1 (en) * | 2019-11-19 | 2023-01-05 | Nibn, The National Institute For Biotechnology In The Negev Ltd. | Novel benzothiophene derivatives and use thereof for stimulating mitochondrial turnover |
IL300000A (en) | 2020-07-22 | 2023-03-01 | Reneo Pharmaceuticals Inc | PPAR agonist - crystalline delta |
WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1011651B1 (de) | 1996-02-02 | 2005-04-27 | Merck & Co., Inc. | Verfahren zur behandlung von diabetes und verwandter krankheitszustände. |
WO1997028149A1 (en) | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
ES2202582T3 (es) | 1996-02-02 | 2004-04-01 | MERCK & CO., INC. | Agentes antidiabeticos. |
EP0904079B1 (de) | 1996-02-02 | 2004-03-24 | Merck & Co., Inc. | Antidiabetisches mittel |
EP0882029B1 (de) | 1996-02-02 | 2003-04-02 | Merck & Co., Inc. | Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit |
US5773469A (en) | 1996-06-18 | 1998-06-30 | Ortho Pharmaceutical Corporation | Diaryl antimicrobial agents |
WO1998027974A1 (en) | 1996-12-23 | 1998-07-02 | Merck & Co., Inc. | Antidiabetic agents |
DE69840510D1 (de) | 1997-07-24 | 2009-03-12 | Astellas Pharma Inc | Medizinische zusammensetzungen mit cholesterin erniedrigender wirkung |
JP2002542218A (ja) | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 新規な化合物、それらの製造および使用 |
GB9914977D0 (en) | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
TWI262185B (en) | 1999-10-01 | 2006-09-21 | Eisai Co Ltd | Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives |
JP2001354671A (ja) | 2000-04-14 | 2001-12-25 | Nippon Chemiphar Co Ltd | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
ATE542805T1 (de) | 2000-08-11 | 2012-02-15 | Nippon Chemiphar Co | Ppar-delta aktivatoren |
GB0031103D0 (en) | 2000-12-20 | 2001-01-31 | Glaxo Group Ltd | Chemical compounds |
MXPA04000891A (es) * | 2001-07-30 | 2004-05-21 | Novo Nordisk As | Nuevos derivados de acido vinilcarboxilico y su uso como antidiabeticos. |
-
2003
- 2003-10-27 BR BR0315683-4A patent/BR0315683A/pt not_active IP Right Cessation
- 2003-10-27 ES ES03757741T patent/ES2345882T3/es not_active Expired - Lifetime
- 2003-10-27 AU AU2003273783A patent/AU2003273783C1/en not_active Ceased
- 2003-10-27 WO PCT/DK2003/000722 patent/WO2004037776A2/en active Application Filing
- 2003-10-27 AT AT03757741T patent/ATE472526T1/de not_active IP Right Cessation
- 2003-10-27 KR KR1020057007096A patent/KR20050061562A/ko not_active Application Discontinuation
- 2003-10-27 EP EP03757741A patent/EP1558572B1/de not_active Expired - Lifetime
- 2003-10-27 DE DE60333211T patent/DE60333211D1/de not_active Expired - Lifetime
- 2003-10-27 RU RU2005116243/04A patent/RU2349582C2/ru not_active IP Right Cessation
- 2003-10-27 PL PL376718A patent/PL376718A1/pl not_active Application Discontinuation
- 2003-10-27 CA CA002503280A patent/CA2503280A1/en not_active Abandoned
- 2003-10-27 JP JP2005501509A patent/JP4708184B2/ja not_active Expired - Fee Related
- 2003-10-27 MX MXPA05004402A patent/MXPA05004402A/es active IP Right Grant
-
2005
- 2005-04-07 ZA ZA2005/02814A patent/ZA200502814B/en unknown
- 2005-05-27 NO NO20052575A patent/NO20052575L/no not_active Application Discontinuation
-
2010
- 2010-04-19 AU AU2010201560A patent/AU2010201560A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2345882T3 (es) | 2010-10-05 |
CA2503280A1 (en) | 2004-05-06 |
KR20050061562A (ko) | 2005-06-22 |
AU2003273783C1 (en) | 2010-08-12 |
ZA200502814B (en) | 2005-12-28 |
MXPA05004402A (es) | 2005-07-26 |
ATE472526T1 (de) | 2010-07-15 |
JP2006503908A (ja) | 2006-02-02 |
EP1558572A2 (de) | 2005-08-03 |
AU2003273783A1 (en) | 2004-05-13 |
EP1558572B1 (de) | 2010-06-30 |
NO20052575L (no) | 2005-05-27 |
BR0315683A (pt) | 2005-08-30 |
AU2010201560A1 (en) | 2010-05-06 |
RU2005116243A (ru) | 2006-01-20 |
AU2003273783B2 (en) | 2010-03-18 |
PL376718A1 (pl) | 2006-01-09 |
JP4708184B2 (ja) | 2011-06-22 |
RU2349582C2 (ru) | 2009-03-20 |
WO2004037776A2 (en) | 2004-05-06 |
WO2004037776A3 (en) | 2004-06-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20052575L (no) | Nye forbindelser, deres fremstilling og anvendelse | |
DE60330757D1 (de) | Verwendung von pyridylamiden als angiogenesehemmer | |
ATE478072T1 (de) | Spiroimidazol-derivate als ppar-modulatoren | |
ATE449604T1 (de) | Pyrazolamid-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren | |
ATE445624T1 (de) | Verbindungen und zusammensetzungen als ppar- modulatoren | |
ATE368031T1 (de) | Neue gamma secretase inhibitoren | |
MX2007009356A (es) | Compuestos y composiciones como moduladores de ppar. | |
CY1111050T1 (el) | Φωσφονικα, μονοφωσφοναμιδικα, διφωσφοναμιδικα για την αγωγη των ιϊκων παθησεων | |
ATE537152T1 (de) | Verbindungen, ihre pharmazeutischen zusammensetzungen und ihre verwendung in der behandlung von stoffwechselstörungen | |
MXPA04000891A (es) | Nuevos derivados de acido vinilcarboxilico y su uso como antidiabeticos. | |
WO2006100081A3 (de) | Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung | |
ATE515494T1 (de) | Neue verbindungen, deren herstellung und verwendung | |
SE0403006D0 (sv) | New compounds | |
ATE412636T1 (de) | Piperazinylpyridinderivate als mittel gegen adipositas | |
BRPI0417858A (pt) | composto, composição farmacêutica, e, uso de uma composição farmacêutica | |
SE0203825D0 (sv) | Novel fused heterocycles and uses thereof | |
BRPI0409763A (pt) | compostos de arila como moduladores de ppars, método de modulação, método de inibição da formação de adipócitos em um mamìfero, método de tratamento de uma doença ou uma condição modulada por ppar e composição farmacêutica | |
DE602005024539D1 (de) | Neue verbindungen, ihre herstellung und verwendung | |
DE602006016323D1 (de) | Oxazol- und thiazol-verbindungen als ppar-modulatoren | |
ATE469882T1 (de) | Neue verbindungen, die sich f r die behandlung von durch ppar vermittelten krankheiten eignen | |
UA106200C2 (uk) | Заміщені похідні оксіндолу та їхнє застосування для лікування захворювань, залежних від вазопресину | |
DE602005024384D1 (de) | Neue verbindungen, ihre herstellung und verwendung | |
ATE475642T1 (de) | Phenoxyessigsäurederivate als ppar-agonisten | |
TW200510427A (en) | Novel fused heterocycles and uses thereof | |
ATE370133T1 (de) | Thiazolinderivate als selektive androgenrezeptormodulatoren (sarms) |