DE60330501D1 - Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung - Google Patents
Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutungInfo
- Publication number
- DE60330501D1 DE60330501D1 DE60330501T DE60330501T DE60330501D1 DE 60330501 D1 DE60330501 D1 DE 60330501D1 DE 60330501 T DE60330501 T DE 60330501T DE 60330501 T DE60330501 T DE 60330501T DE 60330501 D1 DE60330501 D1 DE 60330501D1
- Authority
- DE
- Germany
- Prior art keywords
- bleeding
- connection
- treating nervous
- nervous injury
- injury
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000006378 damage Effects 0.000 title abstract 2
- 208000027418 Wounds and injury Diseases 0.000 title 1
- 230000000740 bleeding effect Effects 0.000 title 1
- 208000014674 injury Diseases 0.000 title 1
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 abstract 2
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 abstract 2
- 229960001661 ursodiol Drugs 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- BHTRKEVKTKCXOH-UHFFFAOYSA-N Taurochenodesoxycholsaeure Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCCS(O)(=O)=O)C)C1(C)CC2 BHTRKEVKTKCXOH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- BHTRKEVKTKCXOH-LBSADWJPSA-N tauroursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)CC1 BHTRKEVKTKCXOH-LBSADWJPSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42521002P | 2002-11-07 | 2002-11-07 | |
| US45161503P | 2003-03-03 | 2003-03-03 | |
| PCT/US2003/031989 WO2004043342A2 (en) | 2002-11-07 | 2003-10-08 | Methods of treating injuries of the nervous system associated with hemorrhage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60330501D1 true DE60330501D1 (de) | 2010-01-21 |
Family
ID=32314576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60330501T Expired - Lifetime DE60330501D1 (de) | 2002-11-07 | 2003-10-08 | Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060135494A1 (https=) |
| EP (1) | EP1575578B1 (https=) |
| JP (1) | JP2006510740A (https=) |
| KR (1) | KR20050103185A (https=) |
| AT (1) | ATE451108T1 (https=) |
| AU (1) | AU2003275495A1 (https=) |
| DE (1) | DE60330501D1 (https=) |
| WO (1) | WO2004043342A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7772220B2 (en) | 2004-10-15 | 2010-08-10 | Seo Hong Yoo | Methods and compositions for reducing toxicity of a pharmaceutical compound |
| US20030044413A1 (en) * | 2000-08-15 | 2003-03-06 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
| US20060204481A1 (en) * | 2003-04-02 | 2006-09-14 | Steer Clifford J | Methods of promoting cell viability |
| DE602005019582D1 (de) | 2004-08-30 | 2010-04-08 | Seo Hong Yoo | Nervenschutzwirkung von aufgelöster udca bei einem fokalen ischämischen modell |
| KR20070084211A (ko) | 2004-10-15 | 2007-08-24 | 유서홍 | 약제학적 화합물의 독성을 감소시키기 위한 방법 및 조성물 |
| JP2008530100A (ja) * | 2005-02-10 | 2008-08-07 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 視覚障害の治療方法 |
| CN101534641A (zh) * | 2006-03-22 | 2009-09-16 | 哈佛大学校长及研究员协会 | 治疗高胆固醇血症和动脉粥样硬化的方法和组合物 |
| KR20180029317A (ko) * | 2016-09-12 | 2018-03-21 | 경상대학교산학협력단 | 간손상 예방, 개선 또는 치료용 조성물 |
| KR101953298B1 (ko) * | 2017-07-18 | 2019-02-28 | 의료법인 성광의료재단 | 우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2090876A1 (en) * | 1991-07-03 | 1993-01-04 | Otsuka Pharmaceutical Co., Ltd. | Apoptosis regulating composition |
| US5656725A (en) * | 1995-05-12 | 1997-08-12 | Apoptosis Technology, Inc. | Peptides and compositions which modulate apoptosis |
| US6544972B1 (en) * | 1997-09-25 | 2003-04-08 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
| JP2002504514A (ja) * | 1998-02-27 | 2002-02-12 | ニュートラマックス ラボラトリーズ，インコーポレイテッド | 肝臓傷害の予防、治療及び修復のためのｌ−エルゴチオネイン、ノゲシ及びｓ−アデノシルメテオニン |
| GB0019290D0 (en) * | 2000-08-04 | 2000-09-27 | Symphar Sa | Methods for inducing apolipoprotein E secretion |
| US20030044413A1 (en) * | 2000-08-15 | 2003-03-06 | Regents Of The University Of Minnesota | Methods of limiting apoptosis of cells |
-
2003
- 2003-10-08 KR KR1020057008192A patent/KR20050103185A/ko not_active Withdrawn
- 2003-10-08 US US10/532,039 patent/US20060135494A1/en not_active Abandoned
- 2003-10-08 AU AU2003275495A patent/AU2003275495A1/en not_active Abandoned
- 2003-10-08 DE DE60330501T patent/DE60330501D1/de not_active Expired - Lifetime
- 2003-10-08 AT AT03759773T patent/ATE451108T1/de not_active IP Right Cessation
- 2003-10-08 EP EP03759773A patent/EP1575578B1/en not_active Expired - Lifetime
- 2003-10-08 WO PCT/US2003/031989 patent/WO2004043342A2/en not_active Ceased
- 2003-10-08 JP JP2005507039A patent/JP2006510740A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003275495A8 (en) | 2004-06-03 |
| US20060135494A1 (en) | 2006-06-22 |
| EP1575578A4 (en) | 2007-10-10 |
| HK1086479A1 (zh) | 2006-09-22 |
| EP1575578B1 (en) | 2009-12-09 |
| EP1575578A2 (en) | 2005-09-21 |
| WO2004043342A3 (en) | 2004-07-15 |
| AU2003275495A1 (en) | 2004-06-03 |
| JP2006510740A (ja) | 2006-03-30 |
| ATE451108T1 (de) | 2009-12-15 |
| WO2004043342A2 (en) | 2004-05-27 |
| KR20050103185A (ko) | 2005-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |