DE60323107D1 - Behandlungs methode und lösung zur hemmung der trübung der hinteren kapsel - Google Patents
Behandlungs methode und lösung zur hemmung der trübung der hinteren kapselInfo
- Publication number
- DE60323107D1 DE60323107D1 DE60323107T DE60323107T DE60323107D1 DE 60323107 D1 DE60323107 D1 DE 60323107D1 DE 60323107 T DE60323107 T DE 60323107T DE 60323107 T DE60323107 T DE 60323107T DE 60323107 D1 DE60323107 D1 DE 60323107D1
- Authority
- DE
- Germany
- Prior art keywords
- agent
- treatment solution
- cells
- treatment
- epithelial cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002775 capsule Substances 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 4
- 210000001542 lens epithelial cell Anatomy 0.000 abstract 3
- 230000007248 cellular mechanism Effects 0.000 abstract 2
- 230000037427 ion transport Effects 0.000 abstract 2
- 230000007246 mechanism Effects 0.000 abstract 2
- 206010036346 Posterior capsule opacification Diseases 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000034994 death Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 230000008723 osmotic stress Effects 0.000 abstract 1
- 238000002203 pretreatment Methods 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/244,878 US7985405B2 (en) | 2002-09-17 | 2002-09-17 | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells |
PCT/IB2003/003600 WO2004026288A1 (en) | 2002-09-17 | 2003-08-28 | A treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60323107D1 true DE60323107D1 (de) | 2008-10-02 |
Family
ID=31991988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60323107T Expired - Lifetime DE60323107D1 (de) | 2002-09-17 | 2003-08-28 | Behandlungs methode und lösung zur hemmung der trübung der hinteren kapsel |
Country Status (10)
Country | Link |
---|---|
US (2) | US7985405B2 (de) |
EP (1) | EP1542663B1 (de) |
JP (1) | JP4502811B2 (de) |
CN (1) | CN1700909B (de) |
AT (1) | ATE405255T1 (de) |
AU (1) | AU2003250495B2 (de) |
CA (1) | CA2499195C (de) |
DE (1) | DE60323107D1 (de) |
HK (1) | HK1085130A1 (de) |
WO (1) | WO2004026288A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7985405B2 (en) | 2002-09-17 | 2011-07-26 | Jin Jun Zhang | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells |
US7875270B2 (en) * | 2002-09-17 | 2011-01-25 | Abbott Medical Optics Inc. | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells |
US20080039416A1 (en) * | 2004-06-02 | 2008-02-14 | Ho Steffan N | Methods for Treating Disease by Modulating an Osmotic Stress Pathway |
GB0419145D0 (en) * | 2004-08-27 | 2004-09-29 | Univ Dundee | Treatment of posterior capsule opacification |
US20060209253A1 (en) * | 2004-10-20 | 2006-09-21 | Giles Brian C | Method and composition for eliminating ocular hypoxic acidosis |
WO2006089288A2 (en) * | 2005-02-19 | 2006-08-24 | Lenticular Research Group Llc | Apparatus and processes for preventing or delaying onset or progression of age-related cataract |
US20120083772A1 (en) * | 2010-09-30 | 2012-04-05 | Curveright Llc | Corneal treatment system and method |
US9622911B2 (en) | 2010-09-30 | 2017-04-18 | Cxl Ophthalmics, Llc | Ophthalmic treatment device, system, and method of use |
CN102526103B (zh) * | 2010-12-07 | 2013-11-13 | 西藏海思科药业集团股份有限公司 | 一种多种微量元素注射液药物组合物及其制备方法 |
WO2013148896A1 (en) | 2012-03-29 | 2013-10-03 | Cxl Ophthalmics, Llc | Ocular treatment solutions, delivery devices and delivery augmentation methods |
EP2830554A1 (de) | 2012-03-29 | 2015-02-04 | CXL Ophthalmics, LLC | Okulares vernetzungssystem und verfahren zum verschliessen von wunden in der augenhornhaut |
US9566301B2 (en) | 2012-03-29 | 2017-02-14 | Cxl Ophthalmics, Llc | Compositions and methods for treating or preventing diseases associated with oxidative stress |
CN106986876B (zh) * | 2017-03-20 | 2019-02-19 | 北京理工大学 | 一种靶向标记眼晶体上皮细胞的荧光探针、其制备及应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3241765A1 (de) | 1982-11-11 | 1984-05-17 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin | Stabile zubereitungen fuer injektionszwecke enthaltend hydrochlorothiazid |
DE3906311A1 (de) | 1989-02-28 | 1990-08-30 | Adatomed Pharma & Med | Behandlungsystem zur verhinderung von nachstarbildung nach einer kataraktoperation |
WO1990009792A1 (en) * | 1989-03-03 | 1990-09-07 | The General Hospital Corporation | Topical application of amiloride or analogues thereof for treatment of inflammation |
DE69535673D1 (de) | 1994-08-30 | 2008-02-07 | Univ Dundee | Mittel zur induktion von apoptosis und zur therapieanwendung |
US6432934B1 (en) * | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
US6399107B1 (en) | 1998-12-22 | 2002-06-04 | Alcon Laboratories, Inc. | Use of inhibitors of gag synthesis for the treatment of corneal haze |
EP1250924A4 (de) * | 2000-01-26 | 2007-03-14 | Kyorin Seiyaku Kk | Augentropfen |
WO2003026744A1 (en) | 2001-09-25 | 2003-04-03 | Alcon, Inc. | The use of epothilones and analogs in conjunction with ophthalmic surgery |
US7985405B2 (en) | 2002-09-17 | 2011-07-26 | Jin Jun Zhang | Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells |
SE0202924D0 (sv) | 2002-10-03 | 2002-10-03 | Pharmacia Groningen Bv | Compositions for preventing posterior capsular opacification and the use therefor |
-
2002
- 2002-09-17 US US10/244,878 patent/US7985405B2/en not_active Expired - Fee Related
-
2003
- 2003-08-28 CA CA2499195A patent/CA2499195C/en not_active Expired - Fee Related
- 2003-08-28 AT AT03797414T patent/ATE405255T1/de not_active IP Right Cessation
- 2003-08-28 CN CN038252317A patent/CN1700909B/zh not_active Expired - Fee Related
- 2003-08-28 JP JP2004537377A patent/JP4502811B2/ja not_active Expired - Fee Related
- 2003-08-28 DE DE60323107T patent/DE60323107D1/de not_active Expired - Lifetime
- 2003-08-28 WO PCT/IB2003/003600 patent/WO2004026288A1/en active IP Right Grant
- 2003-08-28 AU AU2003250495A patent/AU2003250495B2/en not_active Ceased
- 2003-08-28 EP EP03797414A patent/EP1542663B1/de not_active Expired - Lifetime
-
2006
- 2006-05-04 HK HK06105311.5A patent/HK1085130A1/xx not_active IP Right Cessation
-
2007
- 2007-01-08 US US11/620,981 patent/US8114432B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2004026288A1 (en) | 2004-04-01 |
CN1700909A (zh) | 2005-11-23 |
JP2006507252A (ja) | 2006-03-02 |
US8114432B2 (en) | 2012-02-14 |
AU2003250495B2 (en) | 2009-06-04 |
CA2499195A1 (en) | 2004-04-01 |
US20070129286A1 (en) | 2007-06-07 |
US7985405B2 (en) | 2011-07-26 |
AU2003250495A1 (en) | 2004-04-08 |
JP4502811B2 (ja) | 2010-07-14 |
EP1542663A1 (de) | 2005-06-22 |
US20040052823A1 (en) | 2004-03-18 |
ATE405255T1 (de) | 2008-09-15 |
EP1542663B1 (de) | 2008-08-20 |
CA2499195C (en) | 2011-05-24 |
CN1700909B (zh) | 2011-05-18 |
HK1085130A1 (en) | 2006-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |