DE60320224D1 - Hydrolytisch abbaubare polyalkylenoxid-polymere - Google Patents
Hydrolytisch abbaubare polyalkylenoxid-polymereInfo
- Publication number
- DE60320224D1 DE60320224D1 DE60320224T DE60320224T DE60320224D1 DE 60320224 D1 DE60320224 D1 DE 60320224D1 DE 60320224 T DE60320224 T DE 60320224T DE 60320224 T DE60320224 T DE 60320224T DE 60320224 D1 DE60320224 D1 DE 60320224D1
- Authority
- DE
- Germany
- Prior art keywords
- polymer
- hydrolytically
- polyalkylene oxide
- oxide polymers
- hydrolytically removable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/04—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers only
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/18—Block or graft polymers
- C08G64/183—Block or graft polymers containing polyether sequences
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
- C08G65/33337—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group cyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33344—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing carbamate group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33396—Polymers modified by chemical after-treatment with organic compounds containing nitrogen having oxygen in addition to nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polyethers (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35735002P | 2002-02-15 | 2002-02-15 | |
US357350P | 2002-02-15 | ||
PCT/US2003/005113 WO2003070805A1 (en) | 2002-02-15 | 2003-02-14 | Hydrolytically degradable alkylene oxide based polymers |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60320224D1 true DE60320224D1 (de) | 2008-05-21 |
DE60320224T2 DE60320224T2 (de) | 2009-05-14 |
Family
ID=27757601
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60320224T Expired - Lifetime DE60320224T2 (de) | 2002-02-15 | 2003-02-14 | Hydrolytisch abbaubare polyalkylenoxid-polymere |
Country Status (7)
Country | Link |
---|---|
US (2) | US20060239961A1 (de) |
EP (1) | EP1476489B8 (de) |
AT (1) | ATE391742T1 (de) |
AU (1) | AU2003213152A1 (de) |
DE (1) | DE60320224T2 (de) |
ES (1) | ES2304501T3 (de) |
WO (1) | WO2003070805A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE391742T1 (de) * | 2002-02-15 | 2008-04-15 | Nektar Therapeutics Al Corp | Hydrolytisch abbaubare polyalkylenoxid-polymere |
AU2002337479A1 (en) * | 2002-09-04 | 2004-03-29 | Hadasit Medical Research Services & Development Ltd. | Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation |
US7456151B2 (en) | 2004-07-14 | 2008-11-25 | University Of Utah Research Foundation | Promoting angiogenesis with netrin1 polypeptides |
EP1841808B1 (de) * | 2004-12-22 | 2009-01-21 | California Institute Of Technology | Abbaubare polymere und herstellungsverfahren dafür |
WO2006078163A2 (en) * | 2005-01-18 | 2006-07-27 | Dolphys Technologies B.V. | High molecular weight non-ionic surfactants comprising nitrogen or phosphorus containing groups |
WO2006102659A2 (en) * | 2005-03-23 | 2006-09-28 | Nektar Therapeutics Al, Corporation | CONJUGATES OF AN hGH MOIETY AND A POLYMER |
US7517914B2 (en) * | 2005-04-04 | 2009-04-14 | Boston Scientificscimed, Inc. | Controlled degradation materials for therapeutic agent delivery |
US8263109B2 (en) | 2005-05-09 | 2012-09-11 | Boston Scientific Scimed, Inc. | Injectable bulking compositions |
WO2007075534A2 (en) | 2005-12-16 | 2007-07-05 | Nektar Therapeutics Al, Corporation | Polymer conjugates of glp-1 |
JP5312050B2 (ja) * | 2006-02-21 | 2013-10-09 | ネクター セラピューティクス | 分割型の分解性重合体とそれから生成される複合体 |
SI2054074T1 (sl) | 2006-08-04 | 2014-12-31 | Prolong Pharmaceuticals Llc | Modificiran eritropoetin |
WO2008033497A1 (en) * | 2006-09-14 | 2008-03-20 | The Research Foundation Of State University Of New York | Nanostructured smart gel for time release drug delivery |
KR100838809B1 (ko) | 2007-05-03 | 2008-06-17 | 성균관대학교산학협력단 | 겔강도가 우수한 온도 및 피에치 민감성 블록 공중합체 및이의 제조방법과 이를 이용한 약물전달체 |
EP2247645B1 (de) * | 2008-02-13 | 2017-12-06 | Hyperbranch Medical Technology, Inc. | Vernetzte polyalkylenimin-hydrogele mit einstellbaren degradationsraten |
US20100004313A1 (en) * | 2008-02-29 | 2010-01-07 | Tbd | Modified Poloxamers for Gene Expression and Associated Methods |
WO2010033207A1 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
US9399044B2 (en) | 2014-05-28 | 2016-07-26 | International Business Machines Corporation | Antimicrobial cationic polyamines |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3227740A (en) * | 1963-02-25 | 1966-01-04 | Union Oil Co | Preparation of alkyl carbonates |
US4189609A (en) * | 1974-08-19 | 1980-02-19 | Basf Wyandotte Corporation | Multi-block coupled polyoxyalkylene copolymer surfactants |
DE2536121A1 (de) * | 1974-08-19 | 1976-03-04 | Basf Wyandotte Corp | Oberflaechenaktive block-polyoxyalkylencopolymere |
EP0258780B1 (de) * | 1986-09-05 | 1993-06-23 | American Cyanamid Company | Alkylenoxydblöcke enthaltende Polyester und deren Verwendung als Arzneimittelabgabesysteme |
US4866143A (en) * | 1988-04-21 | 1989-09-12 | Basf Corporation | Novel surfactants based on poly(alkylene carbonate)s |
US5330768A (en) * | 1991-07-05 | 1994-07-19 | Massachusetts Institute Of Technology | Controlled drug delivery using polymer/pluronic blends |
US5650234A (en) * | 1994-09-09 | 1997-07-22 | Surface Engineering Technologies, Division Of Innerdyne, Inc. | Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces |
US6201065B1 (en) * | 1995-07-28 | 2001-03-13 | Focal, Inc. | Multiblock biodegradable hydrogels for drug delivery and tissue treatment |
US5861174A (en) * | 1996-07-12 | 1999-01-19 | University Technology Corporation | Temperature sensitive gel for sustained delivery of protein drugs |
ZA978537B (en) * | 1996-09-23 | 1998-05-12 | Focal Inc | Polymerizable biodegradable polymers including carbonate or dioxanone linkages. |
US6258351B1 (en) * | 1996-11-06 | 2001-07-10 | Shearwater Corporation | Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels |
US7074878B1 (en) * | 1999-12-10 | 2006-07-11 | Harris J Milton | Hydrolytically degradable polymers and hydrogels made therefrom |
US6348558B1 (en) | 1999-12-10 | 2002-02-19 | Shearwater Corporation | Hydrolytically degradable polymers and hydrogels made therefrom |
ATE391742T1 (de) | 2002-02-15 | 2008-04-15 | Nektar Therapeutics Al Corp | Hydrolytisch abbaubare polyalkylenoxid-polymere |
AU2003249317B2 (en) * | 2002-07-19 | 2007-08-02 | Institute Of Materials Research And Engineering | Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from |
-
2003
- 2003-02-14 AT AT03709198T patent/ATE391742T1/de not_active IP Right Cessation
- 2003-02-14 US US10/371,996 patent/US20060239961A1/en not_active Abandoned
- 2003-02-14 ES ES03709198T patent/ES2304501T3/es not_active Expired - Lifetime
- 2003-02-14 EP EP03709198A patent/EP1476489B8/de not_active Expired - Lifetime
- 2003-02-14 WO PCT/US2003/005113 patent/WO2003070805A1/en not_active Application Discontinuation
- 2003-02-14 DE DE60320224T patent/DE60320224T2/de not_active Expired - Lifetime
- 2003-02-14 AU AU2003213152A patent/AU2003213152A1/en not_active Abandoned
-
2011
- 2011-05-16 US US13/108,616 patent/US9040060B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU2003213152A1 (en) | 2003-09-09 |
ATE391742T1 (de) | 2008-04-15 |
WO2003070805A1 (en) | 2003-08-28 |
US9040060B2 (en) | 2015-05-26 |
US20060239961A1 (en) | 2006-10-26 |
US20110217343A1 (en) | 2011-09-08 |
ES2304501T3 (es) | 2008-10-16 |
EP1476489B1 (de) | 2008-04-09 |
EP1476489A1 (de) | 2004-11-17 |
EP1476489B8 (de) | 2008-10-08 |
DE60320224T2 (de) | 2009-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8381 | Inventor (new situation) |
Inventor name: BENTLEY, MICHAEL D., HUNTSVILLE, AL 35801, US Inventor name: HARRIS, MILTON J., HUNTSVILLE, AL 35801, US Inventor name: ZHAO, XUAN, HUNTSVILLE, AL 35803, US Inventor name: BATTLE, WILLIAM DUDLEY, HUNTSVILLE, AL 35801, US Inventor name: SHEN, XIAOMING, MADISON, AL 35758, US |
|
8364 | No opposition during term of opposition |