DE60316807D1 - Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren - Google Patents

Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren

Info

Publication number
DE60316807D1
DE60316807D1 DE60316807T DE60316807T DE60316807D1 DE 60316807 D1 DE60316807 D1 DE 60316807D1 DE 60316807 T DE60316807 T DE 60316807T DE 60316807 T DE60316807 T DE 60316807T DE 60316807 D1 DE60316807 D1 DE 60316807D1
Authority
DE
Germany
Prior art keywords
hiv
drug
correlating
medicaments
reverse transcriptase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60316807T
Other languages
English (en)
Other versions
DE60316807T2 (de
Inventor
Hilde Azijn
Bethune Marie-Pierre T M M De
Johan Hendrika Vingerhoets
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen R&D Ireland ULC
Original Assignee
Tibotec Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharmaceuticals Ltd filed Critical Tibotec Pharmaceuticals Ltd
Application granted granted Critical
Publication of DE60316807D1 publication Critical patent/DE60316807D1/de
Publication of DE60316807T2 publication Critical patent/DE60316807T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
DE60316807T 2002-07-01 2003-06-30 Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren Expired - Lifetime DE60316807T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39302502P 2002-07-01 2002-07-01
US393025P 2002-07-01
PCT/EP2003/050279 WO2004003227A1 (en) 2002-07-01 2003-06-30 New mutational profiles in hiv-1 reverse transcriptase correlated with phenotypic drug resistance

Publications (2)

Publication Number Publication Date
DE60316807D1 true DE60316807D1 (de) 2007-11-22
DE60316807T2 DE60316807T2 (de) 2008-07-17

Family

ID=30000963

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60316807T Expired - Lifetime DE60316807T2 (de) 2002-07-01 2003-06-30 Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren

Country Status (6)

Country Link
EP (1) EP1520036B1 (de)
AT (1) ATE375400T1 (de)
AU (1) AU2003251731C1 (de)
CA (1) CA2490918A1 (de)
DE (1) DE60316807T2 (de)
WO (1) WO2004003227A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0817866A1 (de) * 1996-01-26 1998-01-14 Innogenetics N.V. Verfahren für den nachweis von drogen-induzierten mutationen in dem reverse transcriptase gen
NZ516259A (en) * 1999-05-28 2004-02-27 Virco N New mutational profiles in HIV-1 reverse transcriptase correlated with phenotypic drug resistance
BR0011939A (pt) * 1999-06-22 2002-03-12 Virologic Inc Recursos e métodos para monitorar terapia anti-retroviral inibidora de protease e orientar decisões terapêuticas no tratamento de hiv/aids
ES2321809T3 (es) * 2000-10-20 2009-06-12 Virco Bvba Establecimiento de valores e corte biologicos para predecir la resistencia a la terapia.

Also Published As

Publication number Publication date
EP1520036A1 (de) 2005-04-06
AU2003251731C1 (en) 2009-03-05
AU2003251731B2 (en) 2008-09-18
AU2003251731A1 (en) 2004-01-19
EP1520036B1 (de) 2007-10-10
CA2490918A1 (en) 2004-01-08
WO2004003227A1 (en) 2004-01-08
DE60316807T2 (de) 2008-07-17
ATE375400T1 (de) 2007-10-15

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