ATE375400T1 - Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren - Google Patents
Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelierenInfo
- Publication number
- ATE375400T1 ATE375400T1 AT03761599T AT03761599T ATE375400T1 AT E375400 T1 ATE375400 T1 AT E375400T1 AT 03761599 T AT03761599 T AT 03761599T AT 03761599 T AT03761599 T AT 03761599T AT E375400 T1 ATE375400 T1 AT E375400T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv
- correlate
- drug
- drugs
- reverse transcriptase
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 101900297506 Human immunodeficiency virus type 1 group M subtype B Reverse transcriptase/ribonuclease H Proteins 0.000 title 1
- 230000035772 mutation Effects 0.000 title 1
- 230000000869 mutational effect Effects 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000009510 drug design Methods 0.000 abstract 1
- 238000009509 drug development Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39302502P | 2002-07-01 | 2002-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE375400T1 true ATE375400T1 (de) | 2007-10-15 |
Family
ID=30000963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03761599T ATE375400T1 (de) | 2002-07-01 | 2003-06-30 | Neue mutationsmuster in hiv-1 reverser transcriptase, die mit phenotypischer resistenz gegen medikamente korrelieren |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1520036B1 (de) |
| AT (1) | ATE375400T1 (de) |
| AU (1) | AU2003251731C1 (de) |
| CA (1) | CA2490918A1 (de) |
| DE (1) | DE60316807T2 (de) |
| WO (1) | WO2004003227A1 (de) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2215073A1 (en) * | 1996-01-26 | 1997-07-31 | Innogenetics N.V. | Method for detection of drug-induced mutations in the reverse transcriptase gene |
| MXPA01012270A (es) * | 1999-05-28 | 2003-06-24 | Virco Nv | Nuevos perfiles mutacionales en la transcriptasa reversa de vih-1 correlacionadas con resistencia fenotipica a farmacos. |
| WO2000078996A1 (en) * | 1999-06-22 | 2000-12-28 | Virologic, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of hiv/aids |
| WO2002033402A2 (en) * | 2000-10-20 | 2002-04-25 | Virco Bvba | Establishment of biological cut-off values for predicting resistance to therapy |
-
2003
- 2003-06-30 AT AT03761599T patent/ATE375400T1/de active
- 2003-06-30 WO PCT/EP2003/050279 patent/WO2004003227A1/en not_active Ceased
- 2003-06-30 CA CA002490918A patent/CA2490918A1/en not_active Abandoned
- 2003-06-30 EP EP03761599A patent/EP1520036B1/de not_active Expired - Lifetime
- 2003-06-30 DE DE60316807T patent/DE60316807T2/de not_active Expired - Lifetime
- 2003-06-30 AU AU2003251731A patent/AU2003251731C1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE60316807D1 (de) | 2007-11-22 |
| DE60316807T2 (de) | 2008-07-17 |
| CA2490918A1 (en) | 2004-01-08 |
| EP1520036A1 (de) | 2005-04-06 |
| AU2003251731B2 (en) | 2008-09-18 |
| WO2004003227A1 (en) | 2004-01-08 |
| EP1520036B1 (de) | 2007-10-10 |
| AU2003251731A1 (en) | 2004-01-19 |
| AU2003251731C1 (en) | 2009-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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