DE60313173D1 - Synthese von purin-derivaten - Google Patents

Synthese von purin-derivaten

Info

Publication number
DE60313173D1
DE60313173D1 DE60313173T DE60313173T DE60313173D1 DE 60313173 D1 DE60313173 D1 DE 60313173D1 DE 60313173 T DE60313173 T DE 60313173T DE 60313173 T DE60313173 T DE 60313173T DE 60313173 D1 DE60313173 D1 DE 60313173D1
Authority
DE
Germany
Prior art keywords
synthesis
purin derivatives
purin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60313173T
Other languages
English (en)
Other versions
DE60313173T2 (de
Inventor
Lars G Hammarstroem
Nancy Elisabeth Krauss
Sharada Shenvi Labadie
David Bernard Smith
Francisco Xavier Talamas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60313173D1 publication Critical patent/DE60313173D1/de
Publication of DE60313173T2 publication Critical patent/DE60313173T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60313173T 2002-06-27 2003-06-23 Synthese von purin-derivaten Expired - Fee Related DE60313173T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39208102P 2002-06-27 2002-06-27
US392081P 2002-06-27
PCT/EP2003/006568 WO2004002990A2 (en) 2002-06-27 2003-06-23 Synthesis of purine derivatives

Publications (2)

Publication Number Publication Date
DE60313173D1 true DE60313173D1 (de) 2007-05-24
DE60313173T2 DE60313173T2 (de) 2008-01-03

Family

ID=30000809

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313173T Expired - Fee Related DE60313173T2 (de) 2002-06-27 2003-06-23 Synthese von purin-derivaten

Country Status (9)

Country Link
US (1) US7105666B2 (de)
EP (1) EP1519938B1 (de)
JP (1) JP2005535631A (de)
CN (1) CN100427487C (de)
AU (1) AU2003279690A1 (de)
CA (1) CA2488562A1 (de)
DE (1) DE60313173T2 (de)
ES (1) ES2283788T3 (de)
WO (1) WO2004002990A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
AU735127B2 (en) * 1997-08-07 2001-06-28 Regents Of The University Of California, The Purine inhibitor of protein kinases, G proteins and polymerases
AU2002342051B2 (en) * 2001-10-12 2009-06-11 Irm Llc Kinase inhibitor scaffolds and methods for their preparation
GB0407723D0 (en) * 2004-04-05 2004-05-12 Novartis Ag Organic compounds
US8962643B2 (en) 2006-02-24 2015-02-24 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
WO2009079000A1 (en) * 2007-12-17 2009-06-25 Janssen Pharmaceutica N.V. Imidazolopyrimidine modulators of trpv1
PE20091102A1 (es) 2007-12-17 2009-07-25 Janssen Pharmaceutica Nv Moduladores imidazolo-, oxazolo-, y tiazolopirimidina del trpv1
US9408848B2 (en) 2008-08-15 2016-08-09 Georgetown University Fluorescent CDK inhibitors for treatment of cancer
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
AU2021267373A1 (en) 2020-05-06 2022-12-08 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
AU2022388555A1 (en) 2021-11-09 2024-05-02 Ajax Therapeutics, Inc. 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3930005A (en) * 1973-06-15 1975-12-30 Squibb & Sons Inc Antiinflammatory agents and their use
CH652396A5 (de) 1981-12-07 1985-11-15 Ciba Geigy Ag Amino-5-nitropyrimidin-derivate.
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
AUPO912997A0 (en) * 1997-09-11 1997-10-02 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
US6965041B1 (en) * 1999-03-24 2005-11-15 The United States Of America As Represented By The Department Of Health And Human Services N-acylphosphoramidites and their use in oligonucleotide synthesis
EP2433941A1 (de) * 2002-12-11 2012-03-28 Bristol-Myers Squibb Company Verfahren zur Isolierung des antiviralen Mittels [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylencyclopentyl]-6H-purin-6-one

Also Published As

Publication number Publication date
WO2004002990A3 (en) 2004-03-04
CN100427487C (zh) 2008-10-22
EP1519938B1 (de) 2007-04-11
DE60313173T2 (de) 2008-01-03
EP1519938A2 (de) 2005-04-06
JP2005535631A (ja) 2005-11-24
CN1665814A (zh) 2005-09-07
AU2003279690A1 (en) 2004-01-19
US20040034224A1 (en) 2004-02-19
CA2488562A1 (en) 2004-01-08
US7105666B2 (en) 2006-09-12
ES2283788T3 (es) 2007-11-01
WO2004002990A2 (en) 2004-01-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee