DE60237813D1 - Verfahren zum verbessern der effektivität medizinischer einrichtungen durch anhaften von medikamenten an deren oberfläche - Google Patents
Verfahren zum verbessern der effektivität medizinischer einrichtungen durch anhaften von medikamenten an deren oberflächeInfo
- Publication number
- DE60237813D1 DE60237813D1 DE60237813T DE60237813T DE60237813D1 DE 60237813 D1 DE60237813 D1 DE 60237813D1 DE 60237813 T DE60237813 T DE 60237813T DE 60237813 T DE60237813 T DE 60237813T DE 60237813 D1 DE60237813 D1 DE 60237813D1
- Authority
- DE
- Germany
- Prior art keywords
- medicaments
- effectiveness
- improving
- mounting
- medical devices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/02—Pretreatment of the material to be coated
- C23C14/021—Cleaning or etching treatments
- C23C14/022—Cleaning or etching treatments by means of bombardment with energetic particles or radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/22—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
- C23C14/221—Ion beam deposition
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/22—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
- C23C14/50—Substrate holders
- C23C14/505—Substrate holders for rotation of the substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29038901P | 2001-05-11 | 2001-05-11 | |
US31765201P | 2001-09-06 | 2001-09-06 | |
PCT/US2002/015236 WO2002093988A1 (en) | 2001-05-11 | 2002-05-13 | Method and system for improving the effectiveness of medical devices by adhering drugs to the surface thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60237813D1 true DE60237813D1 (de) | 2010-11-11 |
Family
ID=26966151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60237813T Expired - Lifetime DE60237813D1 (de) | 2001-05-11 | 2002-05-13 | Verfahren zum verbessern der effektivität medizinischer einrichtungen durch anhaften von medikamenten an deren oberfläche |
Country Status (5)
Country | Link |
---|---|
US (1) | US7105199B2 (de) |
EP (2) | EP2210626B1 (de) |
JP (1) | JP4617060B2 (de) |
DE (1) | DE60237813D1 (de) |
WO (1) | WO2002093988A1 (de) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
US7923055B2 (en) * | 2001-05-11 | 2011-04-12 | Exogenesis Corporation | Method of manufacturing a drug delivery system |
US20100036502A1 (en) * | 2008-08-07 | 2010-02-11 | Exogenesis Corporation | Medical device for bone implant and method for producing such device |
US8889169B2 (en) * | 2001-05-11 | 2014-11-18 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
US7666462B2 (en) * | 2001-05-11 | 2010-02-23 | Exogenesis Corporation | Method of controlling a drug release rate |
WO2003002243A2 (en) | 2001-06-27 | 2003-01-09 | Remon Medical Technologies Ltd. | Method and device for electrochemical formation of therapeutic species in vivo |
DE60334676D1 (de) | 2003-02-21 | 2010-12-09 | Sorin Biomedica Cardio Srl | Verfahren zur Herstellung eines Stents und entsprechender Stent |
US20050131513A1 (en) * | 2003-12-16 | 2005-06-16 | Cook Incorporated | Stent catheter with a permanently affixed conductor |
ES2764992T3 (es) | 2005-04-04 | 2020-06-05 | Flexible Stenting Solutions Inc | Stent flexible |
US20060233941A1 (en) * | 2005-04-15 | 2006-10-19 | Boston Scientific Scimed, Inc. | Method of coating a medical device utilizing an ion-based thin film deposition technique, a system for coating a medical device, and a medical device produced by the method |
US8840660B2 (en) | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
US8089029B2 (en) | 2006-02-01 | 2012-01-03 | Boston Scientific Scimed, Inc. | Bioabsorbable metal medical device and method of manufacture |
US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US8048150B2 (en) | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
WO2008002778A2 (en) | 2006-06-29 | 2008-01-03 | Boston Scientific Limited | Medical devices with selective coating |
WO2008017028A2 (en) | 2006-08-02 | 2008-02-07 | Boston Scientific Scimed, Inc. | Endoprosthesis with three-dimensional disintegration control |
WO2008033711A2 (en) | 2006-09-14 | 2008-03-20 | Boston Scientific Limited | Medical devices with drug-eluting coating |
US8057534B2 (en) | 2006-09-15 | 2011-11-15 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
JP2010503485A (ja) | 2006-09-15 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 医療用デバイスおよび同デバイスの製造方法 |
ES2368125T3 (es) | 2006-09-15 | 2011-11-14 | Boston Scientific Scimed, Inc. | Endoprótesis bioerosionable con capas inorgánicas bioestables. |
JP2010503489A (ja) | 2006-09-15 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 生体内分解性内部人工器官およびその製造方法 |
CA2663762A1 (en) | 2006-09-18 | 2008-03-27 | Boston Scientific Limited | Endoprostheses |
US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
EP2277563B1 (de) | 2006-12-28 | 2014-06-25 | Boston Scientific Limited | Biologisch abbaubare endoprothesen und verfahren zur herstellung derselben. |
US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
US8067054B2 (en) * | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
US7976915B2 (en) | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
US7942926B2 (en) | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US8002823B2 (en) | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
JP2010533563A (ja) | 2007-07-19 | 2010-10-28 | ボストン サイエンティフィック リミテッド | 吸着抑制表面を有する内部人工器官 |
US8815273B2 (en) | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
US7931683B2 (en) | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
US8221822B2 (en) | 2007-07-31 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
US7988723B2 (en) | 2007-08-02 | 2011-08-02 | Flexible Stenting Solutions, Inc. | Flexible stent |
JP2010535541A (ja) | 2007-08-03 | 2010-11-25 | ボストン サイエンティフィック リミテッド | 広い表面積を有する医療器具用のコーティング |
US8052745B2 (en) | 2007-09-13 | 2011-11-08 | Boston Scientific Scimed, Inc. | Endoprosthesis |
US8377460B2 (en) * | 2007-09-14 | 2013-02-19 | Exogenesis Corporation | Method for modifying the wettability and/or other biocompatibility characteristics of a surface of a biological material by the application of gas cluster ion beam technology and biological materials made thereby |
US20100227523A1 (en) * | 2007-09-14 | 2010-09-09 | Exogenesis Corporation | Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby |
WO2009036373A2 (en) * | 2007-09-14 | 2009-03-19 | Exogenesis Corporation | Method and system for modifying the wettability characteristics of a surface of a medical device by the application of gas cluster ion beam technology and medical devices made thereby |
US9144627B2 (en) | 2007-09-14 | 2015-09-29 | Exogenesis Corporation | Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby |
EP2192993A4 (de) * | 2007-10-01 | 2012-02-15 | Exogenesis Corp | Verfahren und system zur beschichtung der oberfläche eines medizinischen gerätes mit einem therapeutischen wirkstoff und auf diese weise hergestellte wirkstofffreisetzende medizinische geräte |
US7938855B2 (en) | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
US8029554B2 (en) | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US20090186068A1 (en) * | 2008-01-18 | 2009-07-23 | Chameleon Scientific Corporation | Atomic plasma deposited coatings for drug release |
US20090226598A1 (en) * | 2008-02-11 | 2009-09-10 | Boston Scientific Scimed, Inc. | Substrate Coating Apparatus Having a Solvent Vapor Emitter |
JP5581311B2 (ja) | 2008-04-22 | 2014-08-27 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 無機材料のコーティングを有する医療デバイス及びその製造方法 |
WO2009132176A2 (en) | 2008-04-24 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
US7998192B2 (en) | 2008-05-09 | 2011-08-16 | Boston Scientific Scimed, Inc. | Endoprostheses |
US8236046B2 (en) | 2008-06-10 | 2012-08-07 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
WO2009155328A2 (en) | 2008-06-18 | 2009-12-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
US7985252B2 (en) | 2008-07-30 | 2011-07-26 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
US20100036482A1 (en) * | 2008-08-07 | 2010-02-11 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
US8382824B2 (en) | 2008-10-03 | 2013-02-26 | Boston Scientific Scimed, Inc. | Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides |
US9149376B2 (en) | 2008-10-06 | 2015-10-06 | Cordis Corporation | Reconstrainable stent delivery system |
US8231980B2 (en) | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
US8267992B2 (en) | 2009-03-02 | 2012-09-18 | Boston Scientific Scimed, Inc. | Self-buffering medical implants |
US8071156B2 (en) | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
US20100233227A1 (en) * | 2009-03-10 | 2010-09-16 | Boston Scientific Scimed, Inc. | Medical devices having carbon drug releasing layers |
WO2010105102A1 (en) * | 2009-03-11 | 2010-09-16 | Exogenesis Corporation | Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby |
EP2405891B1 (de) * | 2009-03-11 | 2019-07-03 | Exogenesis Corporation | Verfahren zur modifikation der befeuchtbarkeit und/oder anderer biokompatibilitätseigenschaften der oberfläche eines biologischen materials durch anwendung einer gascluster-ionenstrahltechnologie sowie in diesem verfahren hergestellte biologische materialien |
US8287937B2 (en) | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
WO2011119573A1 (en) | 2010-03-23 | 2011-09-29 | Boston Scientific Scimed, Inc. | Surface treated bioerodible metal endoprostheses |
US20130149459A1 (en) * | 2010-07-02 | 2013-06-13 | Aptar France Sas | Method for the surface treatment of a fluid product dispensing device |
US20170303383A1 (en) * | 2010-08-23 | 2017-10-19 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
US10181402B2 (en) | 2010-08-23 | 2019-01-15 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
US9799488B2 (en) * | 2010-08-23 | 2017-10-24 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology |
US10670960B2 (en) | 2010-08-23 | 2020-06-02 | Exogenesis Corporation | Enhanced high aspect ratio etch performance using accelerated neutral beams derived from gas-cluster ion beams |
WO2013028529A1 (en) * | 2011-08-19 | 2013-02-28 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
US10202684B2 (en) | 2010-08-23 | 2019-02-12 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
US11199769B2 (en) | 2010-08-23 | 2021-12-14 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology |
CN103180030B (zh) | 2010-08-23 | 2017-04-12 | 艾克索乔纳斯公司 | 基于气体团簇离子束技术的中性射束处理方法和设备 |
US10825685B2 (en) | 2010-08-23 | 2020-11-03 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
US10556042B2 (en) | 2011-08-19 | 2020-02-11 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
WO2013028761A1 (en) * | 2011-08-22 | 2013-02-28 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
US9114195B2 (en) | 2011-08-22 | 2015-08-25 | Exogenesis Corporation | Method for modifying the wettability and other biocompatibility characteristics of a surface of a biological material by the application of beam technology and biological materials made thereby |
JP2014525817A (ja) | 2011-08-22 | 2014-10-02 | エクソジェネシス コーポレーション | 物体表面の生物活性特徴の向上方法ならびにそれにより向上された表面 |
RU2648961C2 (ru) * | 2012-02-22 | 2018-03-28 | Эксодженезис Корпорейшн | Способ обработки пучком нейтральных частиц, основанный на технологии обработки пучком газовых кластерных ионов, и полученные таким образом изделия |
GB2546319B (en) | 2016-01-15 | 2019-07-03 | Cook Medical Technologies Llc | Coated medical device and method of coating such a device |
DE112022000720T5 (de) * | 2021-01-22 | 2023-11-16 | Exogenesis Corporation | Mit einem beschleunigten neutralen atomstrahl (bnas) modifiziertes polypropylen zur reduzierung der bakterienbesiedlung ohne antibiotika |
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US4968006A (en) * | 1989-07-21 | 1990-11-06 | Spire Corporation | Ion implantation of spherical surfaces |
US5123924A (en) | 1990-04-25 | 1992-06-23 | Spire Corporation | Surgical implants and method |
JP2662321B2 (ja) | 1991-05-31 | 1997-10-08 | 科学技術振興事業団 | 超低速クラスターイオンビームによる表面処理方法 |
US5419760A (en) | 1993-01-08 | 1995-05-30 | Pdt Systems, Inc. | Medicament dispensing stent for prevention of restenosis of a blood vessel |
US5814194A (en) | 1994-10-20 | 1998-09-29 | Matsushita Electric Industrial Co., Ltd | Substrate surface treatment method |
US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
US5609629A (en) * | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
JP3770970B2 (ja) * | 1996-08-28 | 2006-04-26 | 昭和ゴム株式会社 | アルゴンガスクラスターイオンビームによる医療用物品の表面処理方法 |
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US6331227B1 (en) * | 1999-12-14 | 2001-12-18 | Epion Corporation | Enhanced etching/smoothing of dielectric surfaces |
AU2001277862A1 (en) * | 2000-07-10 | 2002-01-21 | Epion Corporation | Improving effectiveness of introaocular lenses by gcib |
EP1301652B1 (de) * | 2000-07-10 | 2013-09-11 | Exogenesis Corporation | Verbesserung der effektivität künstlicher hüftgelenke durch gcib |
US6676989B2 (en) * | 2000-07-10 | 2004-01-13 | Epion Corporation | Method and system for improving the effectiveness of medical stents by the application of gas cluster ion beam technology |
US6716444B1 (en) * | 2000-09-28 | 2004-04-06 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
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US6641607B1 (en) * | 2000-12-29 | 2003-11-04 | Advanced Cardiovascular Systems, Inc. | Double tube stent |
US7077982B2 (en) * | 2001-03-23 | 2006-07-18 | Fuji Photo Film Co., Ltd. | Molecular electric wire, molecular electric wire circuit using the same and process for producing the molecular electric wire circuit |
US6764505B1 (en) * | 2001-04-12 | 2004-07-20 | Advanced Cardiovascular Systems, Inc. | Variable surface area stent |
US6863786B2 (en) * | 2001-05-09 | 2005-03-08 | Exogenesis Biomedical Technology | Method and system for improving the effectiveness of artificial joints by the application of gas cluster ion beam technology |
US20050025805A1 (en) * | 2003-07-28 | 2005-02-03 | Adam Heller | Osmium compounds for reduction of adverse inflammation |
-
2002
- 2002-05-13 WO PCT/US2002/015236 patent/WO2002093988A1/en active Application Filing
- 2002-05-13 EP EP10158600.6A patent/EP2210626B1/de not_active Expired - Lifetime
- 2002-05-13 JP JP2002590721A patent/JP4617060B2/ja not_active Expired - Fee Related
- 2002-05-13 US US10/144,919 patent/US7105199B2/en not_active Expired - Lifetime
- 2002-05-13 EP EP02769731A patent/EP1393601B1/de not_active Expired - Lifetime
- 2002-05-13 DE DE60237813T patent/DE60237813D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2002093988A1 (en) | 2002-11-21 |
JP4617060B2 (ja) | 2011-01-19 |
EP1393601B1 (de) | 2010-09-29 |
US7105199B2 (en) | 2006-09-12 |
US20020188324A1 (en) | 2002-12-12 |
JP2004532081A (ja) | 2004-10-21 |
EP2210626A1 (de) | 2010-07-28 |
EP2210626B1 (de) | 2015-01-21 |
EP1393601A1 (de) | 2004-03-03 |
EP1393601A4 (de) | 2007-03-21 |
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