DE60235499D1 - ZELLWACHSTUMSHEMMER MIT ANTI-PepT-ANTIKÖRPER - Google Patents

ZELLWACHSTUMSHEMMER MIT ANTI-PepT-ANTIKÖRPER

Info

Publication number
DE60235499D1
DE60235499D1 DE60235499T DE60235499T DE60235499D1 DE 60235499 D1 DE60235499 D1 DE 60235499D1 DE 60235499 T DE60235499 T DE 60235499T DE 60235499 T DE60235499 T DE 60235499T DE 60235499 D1 DE60235499 D1 DE 60235499D1
Authority
DE
Germany
Prior art keywords
pept
cell growth
antibody
hemmer
cytotoxic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235499T
Other languages
English (en)
Inventor
Tatsuhiko Kodama
Takao Hamakubo
Ryoichi Saitoh
Iwao Ohizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60235499D1 publication Critical patent/DE60235499D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60235499T 2001-12-04 2002-12-04 ZELLWACHSTUMSHEMMER MIT ANTI-PepT-ANTIKÖRPER Expired - Lifetime DE60235499D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001369608 2001-12-04
JP2002164834 2002-06-05
PCT/JP2002/012708 WO2003047621A1 (fr) 2001-12-04 2002-12-04 Inhibiteur de la proliferation cellulaire contenant un anticorps dirige contre pept

Publications (1)

Publication Number Publication Date
DE60235499D1 true DE60235499D1 (de) 2010-04-08

Family

ID=26624860

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235499T Expired - Lifetime DE60235499D1 (de) 2001-12-04 2002-12-04 ZELLWACHSTUMSHEMMER MIT ANTI-PepT-ANTIKÖRPER

Country Status (7)

Country Link
US (1) US7666998B2 (de)
EP (1) EP1462113B1 (de)
JP (2) JPWO2003047621A1 (de)
AT (1) ATE458498T1 (de)
AU (1) AU2002354374A1 (de)
DE (1) DE60235499D1 (de)
WO (1) WO2003047621A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003033024A1 (ja) * 2001-10-16 2006-07-06 中外製薬株式会社 細胞増殖抑制剤
AU2002354374A1 (en) 2001-12-04 2003-06-17 Chugai Seiyaku Kabushiki Kaisha CELL PROLIFERATION INHIBITOR CONTAINING ANTI-PepT ANTIBODY
US7666610B2 (en) 2002-03-29 2010-02-23 Chugai Seiyaku Kabushiki Kaisha Expressing transporters on viral envelopes
WO2003104453A1 (ja) * 2002-06-05 2003-12-18 中外製薬株式会社 抗体作製方法
WO2004087762A1 (ja) * 2003-03-28 2004-10-14 Chugai Seiyaku Kabushiki Kaisha ペプチドトランスポーターの輸送活性を阻害する抗体
EP1731032B1 (de) 2004-03-31 2016-10-19 Chugai Seiyaku Kabushiki Kaisha Transgene-maüse für gen einer lösliche form von membran-protein zur produktion von antikörper gegen ein gezielte antigen
US11040082B2 (en) * 2014-08-06 2021-06-22 Georgia State University Research Foundation, Inc. Compositions and methods for treating colorectal cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL108499A (en) 1993-02-04 2000-02-29 Lilly Co Eli Mammalian influx peptide transporter
US5500346A (en) 1993-06-29 1996-03-19 Eli Lilly And Company Monoclonal antibodies to human influx peptide transporter
US5849525A (en) 1994-03-09 1998-12-15 Brigham And Women's Hospital, Inc. Compositions corresponding to a proton-coupled peptide transporter and methods of making and using same
JPH08134100A (ja) 1994-11-09 1996-05-28 Unitika Ltd 糖鎖特異的抗体の製造方法
WO1997019919A1 (fr) 1995-11-30 1997-06-05 C & C Research Laboratories Derives de sulfamides
FR2761994B1 (fr) 1997-04-11 1999-06-18 Centre Nat Rech Scient Preparation de recepteurs membranaires a partir de baculovirus extracellulaires
JPH11172A (ja) 1997-06-11 1999-01-06 Snow Brand Milk Prod Co Ltd ペプチド輸送タンパク質遺伝子を含むｄｎａ、ベクター及び微生物
US6867017B1 (en) * 1998-10-23 2005-03-15 The United States Of America As Represented By The Department Of Health And Human Services ATP-binding transporter (ABC7) and methods for detection of anemia and ataxia
EP1137769B1 (de) 1998-11-10 2008-09-03 University Of Rochester Methoden zu herstellung von genbanken
JP4552056B2 (ja) 1999-11-15 2010-09-29 独立行政法人科学技術振興機構 後天的免疫寛容の獲得方法
JP2001197846A (ja) 2000-01-18 2001-07-24 Ys New Technology Kenkyusho:Kk 免疫寛容動物の作製方法
JPWO2003033024A1 (ja) 2001-10-16 2006-07-06 中外製薬株式会社 細胞増殖抑制剤
AU2002354374A1 (en) 2001-12-04 2003-06-17 Chugai Seiyaku Kabushiki Kaisha CELL PROLIFERATION INHIBITOR CONTAINING ANTI-PepT ANTIBODY
US7666610B2 (en) 2002-03-29 2010-02-23 Chugai Seiyaku Kabushiki Kaisha Expressing transporters on viral envelopes
WO2003104453A1 (ja) 2002-06-05 2003-12-18 中外製薬株式会社 抗体作製方法
WO2004087762A1 (ja) * 2003-03-28 2004-10-14 Chugai Seiyaku Kabushiki Kaisha ペプチドトランスポーターの輸送活性を阻害する抗体
EP1731032B1 (de) 2004-03-31 2016-10-19 Chugai Seiyaku Kabushiki Kaisha Transgene-maüse für gen einer lösliche form von membran-protein zur produktion von antikörper gegen ein gezielte antigen

Also Published As

Publication number Publication date
EP1462113A1 (de) 2004-09-29
US7666998B2 (en) 2010-02-23
WO2003047621A1 (fr) 2003-06-12
US20050281825A1 (en) 2005-12-22
JP2010013471A (ja) 2010-01-21
EP1462113B1 (de) 2010-02-24
AU2002354374A1 (en) 2003-06-17
JPWO2003047621A1 (ja) 2005-04-14
ATE458498T1 (de) 2010-03-15
EP1462113A4 (de) 2004-12-29

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