DE60232477D1 - Verfahren zur Beseitigung von Viren und Prionen aus Immunglobulinzusammensetzungen - Google Patents
Verfahren zur Beseitigung von Viren und Prionen aus ImmunglobulinzusammensetzungenInfo
- Publication number
- DE60232477D1 DE60232477D1 DE60232477T DE60232477T DE60232477D1 DE 60232477 D1 DE60232477 D1 DE 60232477D1 DE 60232477 T DE60232477 T DE 60232477T DE 60232477 T DE60232477 T DE 60232477T DE 60232477 D1 DE60232477 D1 DE 60232477D1
- Authority
- DE
- Germany
- Prior art keywords
- prions
- immunoglobulin
- immunoglobulin compositions
- methods
- eliminating viruses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 4
- 102000018358 immunoglobulin Human genes 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 102000029797 Prion Human genes 0.000 title abstract 2
- 108091000054 Prion Proteins 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 239000012141 concentrate Substances 0.000 abstract 1
- 238000011026 diafiltration Methods 0.000 abstract 1
- 229940072221 immunoglobulins Drugs 0.000 abstract 1
- 238000001728 nano-filtration Methods 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 229940068968 polysorbate 80 Drugs 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28080701P | 2001-04-02 | 2001-04-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60232477D1 true DE60232477D1 (de) | 2009-07-16 |
Family
ID=23074738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60232477T Expired - Lifetime DE60232477D1 (de) | 2001-04-02 | 2002-04-02 | Verfahren zur Beseitigung von Viren und Prionen aus Immunglobulinzusammensetzungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040110931A1 (de) |
EP (1) | EP1247818B1 (de) |
JP (1) | JP4523222B2 (de) |
AT (1) | ATE432948T1 (de) |
AU (1) | AU784808B2 (de) |
CA (1) | CA2379901A1 (de) |
DE (1) | DE60232477D1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1511391B1 (de) * | 2002-05-23 | 2012-05-02 | Ortho-Clinical Diagnostics, Inc. | Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration |
CA2497364C (en) * | 2002-09-11 | 2013-03-19 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
EP1614424B1 (de) * | 2003-04-09 | 2015-07-22 | The Chemo-Sero-Therapeutic Research Institute | Verfahren zur herstellung einer albumin-zubereitung |
WO2006042541A1 (en) * | 2004-10-21 | 2006-04-27 | Statens Serum Institut | A method comprising nanofiltration to obtain an mbl product safe from infectious agents and the product obtainable by this method |
PT1809663E (pt) * | 2004-11-09 | 2008-10-02 | Ares Trading Sa | Um cesto para cultivo de marisco |
AU2005229674B2 (en) * | 2004-11-18 | 2010-11-04 | Kedrion Melville Inc. | Low concentration solvent/detergent process of immuneglobulin with pre-treatment |
ES2664924T3 (es) | 2005-08-26 | 2018-04-24 | Ares Trading S.A. | Procedimiento para la preparación del interferón beta glicosilado |
AU2006323925B2 (en) | 2005-12-09 | 2012-08-02 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
EP1800673A3 (de) * | 2005-12-23 | 2007-08-15 | Canadian Blood Services | Nitrophenyle und verwandte Zusammensetzungen sowie Thimerosal zur Hemmung von immunspezifischer Zell- oder Gewebezerstörung |
AU2010294192A1 (en) | 2009-09-10 | 2012-04-05 | Lonza Biologics Plc | Method and system for polypeptide purification |
WO2015140751A1 (en) * | 2014-03-21 | 2015-09-24 | Boreal Invest | Terminal nanofiltration of solubilized protein compositions for removal of immunogenic aggregates |
IL285529B2 (en) * | 2014-05-13 | 2023-03-01 | Amgen Inc | Process control systems and methods for the use of filters and filtration processes |
CN106950326B (zh) * | 2017-03-10 | 2018-05-29 | 武汉大学 | 一种化学标记结合lc-ms的方法及其在核苷酸分析中的应用 |
CA3098609A1 (en) * | 2018-05-17 | 2019-11-21 | Csl Behring Ag | Method and system of protein extraction |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2390074A (en) * | 1942-02-09 | 1945-12-04 | Research Corp | Protein product and process |
US3449314A (en) * | 1966-06-03 | 1969-06-10 | Ortho Pharma Corp | Preparation of anti-rh globulin from human plasma |
US3916026A (en) * | 1968-09-19 | 1975-10-28 | Biotest Serum Institut Gmbh | Method for the preparation of gamma-globulin suitable for intravenous use |
US4021540A (en) * | 1975-07-28 | 1977-05-03 | Ortho Diagnostics Inc. | Preparation of a hepatitis B immune globulin and use thereof as a prophylactic material |
US4859340A (en) * | 1976-03-15 | 1989-08-22 | Cuno, Incorporated | Filter sheet |
DE2624373C2 (de) * | 1976-05-31 | 1983-02-03 | Arnold Dr. 8782 Karlstadt Seufert | Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII |
US4590002A (en) * | 1984-12-10 | 1986-05-20 | Ortho Diagnostic Systems, Inc. | Methods for preparation of highly purified, gamma globulins free of hepatitis-B-virus infectivity |
US5173415A (en) * | 1986-01-20 | 1992-12-22 | Japan Chemical Research Co., Ltd. | Process for removal of viruses from solutions of physiologically active substances |
DE3641115A1 (de) * | 1986-12-02 | 1988-06-16 | Lentia Gmbh | Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins |
US5115101A (en) * | 1988-06-08 | 1992-05-19 | Miles Inc. | Removal of protein A from antibody preparations |
FR2639645B1 (fr) * | 1988-11-25 | 1992-05-29 | Elf Aquitaine | Solutions liquides concentrees de polysaccharides |
DE4137996A1 (de) * | 1991-11-19 | 1993-05-27 | Behringwerke Ag | Verfahren zur herstellung eines virussicheren thrombinkonzentrates |
US5858641A (en) * | 1996-09-17 | 1999-01-12 | Shanbrom Technologies, Llc | Disinfectant dye removal from blood and blood fractions using a porous poly(vinyl alcohol-acetal) copolymer |
US6221614B1 (en) * | 1997-02-21 | 2001-04-24 | The Regents Of The University Of California | Removal of prions from blood, plasma and other liquids |
US6096872A (en) * | 1997-10-14 | 2000-08-01 | Ortho Diagnostic Systems, Inc. | Viral clearance process |
FR2772381B1 (fr) * | 1997-12-15 | 2001-06-08 | Lab Francais Du Fractionnement | Procede de preparation par filtration d'une solution de facteur viii securisee viralement |
ES2218118T5 (es) * | 1999-01-19 | 2011-04-06 | Common Services Agency | Tratamiento de líquidos que contienen proteínas. |
US6166187A (en) * | 1999-03-05 | 2000-12-26 | The Regents Of The University Of California | Method of concentrating prion proteins in blood samples |
US6270672B1 (en) * | 1999-08-06 | 2001-08-07 | Baxter Aktiengesellschaft | Devices and methods for removing pathogens from biological fluids |
-
2002
- 2002-03-28 AU AU29316/02A patent/AU784808B2/en not_active Ceased
- 2002-04-02 AT AT02252375T patent/ATE432948T1/de not_active IP Right Cessation
- 2002-04-02 CA CA002379901A patent/CA2379901A1/en not_active Abandoned
- 2002-04-02 DE DE60232477T patent/DE60232477D1/de not_active Expired - Lifetime
- 2002-04-02 US US10/114,160 patent/US20040110931A1/en not_active Abandoned
- 2002-04-02 EP EP02252375A patent/EP1247818B1/de not_active Revoked
- 2002-04-02 JP JP2002100317A patent/JP4523222B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2003064099A (ja) | 2003-03-05 |
JP4523222B2 (ja) | 2010-08-11 |
EP1247818A2 (de) | 2002-10-09 |
EP1247818A3 (de) | 2004-03-03 |
AU784808B2 (en) | 2006-06-29 |
ATE432948T1 (de) | 2009-06-15 |
EP1247818B1 (de) | 2009-06-03 |
US20040110931A1 (en) | 2004-06-10 |
AU2931602A (en) | 2002-10-03 |
CA2379901A1 (en) | 2002-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |