DE60231428D1 - Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff - Google Patents
Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoffInfo
- Publication number
- DE60231428D1 DE60231428D1 DE60231428T DE60231428T DE60231428D1 DE 60231428 D1 DE60231428 D1 DE 60231428D1 DE 60231428 T DE60231428 T DE 60231428T DE 60231428 T DE60231428 T DE 60231428T DE 60231428 D1 DE60231428 D1 DE 60231428D1
- Authority
- DE
- Germany
- Prior art keywords
- polyethylene glycol
- aerosol compositions
- functionalized polyethylene
- medical aerosol
- glycol agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34278701P | 2001-12-21 | 2001-12-21 | |
| PCT/US2002/041299 WO2003059317A2 (en) | 2001-12-21 | 2002-12-20 | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60231428D1 true DE60231428D1 (de) | 2009-04-16 |
Family
ID=23343270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60231428T Expired - Lifetime DE60231428D1 (de) | 2001-12-21 | 2002-12-20 | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7718162B2 (enExample) |
| EP (1) | EP1458357B1 (enExample) |
| JP (1) | JP4959919B2 (enExample) |
| AT (1) | ATE424186T1 (enExample) |
| AU (1) | AU2002367032B8 (enExample) |
| CA (1) | CA2470520A1 (enExample) |
| DE (1) | DE60231428D1 (enExample) |
| WO (1) | WO2003059317A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7718162B2 (en) | 2001-12-21 | 2010-05-18 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
| EP1458354A1 (en) * | 2001-12-21 | 2004-09-22 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
| CA2470498A1 (en) * | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
| GB0614621D0 (en) | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB0620700D0 (en) | 2006-10-19 | 2006-11-29 | 3M Innovative Properties Co | Metered dose valves and dispensers |
| EP2480197B1 (en) | 2009-09-25 | 2015-11-11 | Dr. Reddy's Laboratories Ltd. | Formulations comprising triptan compounds |
| US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
| EP3020393B1 (en) | 2009-12-16 | 2020-10-07 | 3M Innovative Properties Company | Formulations and methods for controlling mdi particle size delivery |
| GB201118188D0 (en) | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| GB201210580D0 (en) | 2012-06-14 | 2012-08-01 | 3M Innovative Properties Co | Metered dose dispensing valve |
| GB201221063D0 (en) | 2012-11-23 | 2013-01-09 | 3M Innovative Properties Co | Metered dose dispensing valve |
| EP3649175A1 (en) | 2017-07-07 | 2020-05-13 | Basf Se | Alkoxylated esteramines and salts thereof |
| CN117042803A (zh) * | 2021-12-02 | 2023-11-10 | 丽泽润有限公司 | 具有多功能应用的天然赋形剂及其制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1163028B (de) * | 1960-03-09 | 1964-02-13 | Hoechst Ag | Verfahren zur Polymerisation von Vinylchlorid |
| WO1987005210A1 (fr) * | 1986-03-10 | 1987-09-11 | Kurt Burghart | Produit pharmaceutique et son procede de preparation |
| ES2038696T3 (es) * | 1986-03-10 | 1996-07-16 | Burghart Kurt | Procedimiento para producir un preparado farmaceutico. |
| US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5342940A (en) * | 1989-05-27 | 1994-08-30 | Sumitomo Pharmaceuticals Company, Limited | Polyethylene glycol derivatives, process for preparing the same |
| SK392592A3 (en) * | 1990-06-29 | 1994-07-06 | Fisons Plc | Pressure aerosol composition |
| AU5171293A (en) * | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
| ES2129117T3 (es) * | 1992-12-09 | 1999-06-01 | Boehringer Ingelheim Pharma | Formulaciones en disolucion en forma de aerosol medicinales estabilizadas. |
| DE69405719T2 (de) * | 1993-03-17 | 1998-01-15 | Minnesota Mining & Mfg | Aerosolzubereitung, enthaltend ein aus einem diol-disäure-derivat abgeleitetes dispergiermittel |
| KR100321649B1 (ko) * | 1993-03-17 | 2002-07-22 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | 에스테르,아미드또는머캅토에스테르로부터유도된분산보조제를함유하는에어로졸제제 |
| US5492688A (en) * | 1993-04-28 | 1996-02-20 | The Center For Innovative Technology | Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent |
| PT731688E (pt) * | 1993-12-02 | 2003-07-31 | Abbott Lab | Formulacoes de farmacos em aerossol para utilizacao com propulsores sem cfc |
| US5508023A (en) * | 1994-04-11 | 1996-04-16 | The Center For Innovative Technology | Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant |
| US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US6517860B1 (en) * | 1996-12-31 | 2003-02-11 | Quadrant Holdings Cambridge, Ltd. | Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery |
| US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| US6218353B1 (en) * | 1997-08-27 | 2001-04-17 | Micell Technologies, Inc. | Solid particulate propellant systems and aerosol containers employing the same |
| US6136294C1 (en) * | 1998-09-22 | 2002-09-24 | Aeropharm Technology Inc | Amino acid stabilized medical aerosol formulation |
| EP1124535B1 (en) * | 1998-10-27 | 2002-12-11 | Alcon Laboratories, Inc. | Preservative system for topically administrable pharmaceutical compositions containing a fatty acid/amino acid soap |
| US6258857B1 (en) * | 1999-02-04 | 2001-07-10 | Kyowa Industrial Co., Ltd. | Internal liquid composition contained as internal liquid in a releasing container and releasing container product |
| GB0016876D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Novel formulation |
| US7217409B2 (en) | 2000-09-22 | 2007-05-15 | Smithkline Beecham Corporation | Alkanoic acid derivatives |
| AR033903A1 (es) * | 2001-05-21 | 2004-01-07 | Inhale Therapeutic Syst | Una composicion de insulina modificada quimicamente para la administracion pulmonar |
| GB0125127D0 (en) | 2001-10-19 | 2001-12-12 | Glaxo Group Ltd | Compounds |
| CA2470498A1 (en) * | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
| US7718162B2 (en) | 2001-12-21 | 2010-05-18 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
-
2002
- 2002-12-20 US US10/327,200 patent/US7718162B2/en not_active Expired - Fee Related
- 2002-12-20 EP EP02806511A patent/EP1458357B1/en not_active Expired - Lifetime
- 2002-12-20 DE DE60231428T patent/DE60231428D1/de not_active Expired - Lifetime
- 2002-12-20 AU AU2002367032A patent/AU2002367032B8/en not_active Ceased
- 2002-12-20 CA CA002470520A patent/CA2470520A1/en not_active Abandoned
- 2002-12-20 JP JP2003559480A patent/JP4959919B2/ja not_active Expired - Fee Related
- 2002-12-20 WO PCT/US2002/041299 patent/WO2003059317A2/en not_active Ceased
- 2002-12-20 AT AT02806511T patent/ATE424186T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002367032B2 (en) | 2008-09-25 |
| CA2470520A1 (en) | 2003-07-24 |
| AU2002367032B8 (en) | 2008-10-23 |
| US7718162B2 (en) | 2010-05-18 |
| JP4959919B2 (ja) | 2012-06-27 |
| JP2006502086A (ja) | 2006-01-19 |
| ATE424186T1 (de) | 2009-03-15 |
| AU2002367032A1 (en) | 2003-07-30 |
| WO2003059317A2 (en) | 2003-07-24 |
| EP1458357A2 (en) | 2004-09-22 |
| WO2003059317A3 (en) | 2003-11-20 |
| US20030152521A1 (en) | 2003-08-14 |
| EP1458357B1 (en) | 2009-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60231428D1 (de) | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff | |
| BR9909394A (pt) | Composição de aerossol, composição farmacêutica, recipiente, dispositivo de inalação, processo para preparar uma composição de aerossol, mistura de um primeiro material particulado, e, processo para administrar um medicamento particulado | |
| EA200401006A1 (ru) | Аэрозольные препараты для внутрилёгочного введения лекарств с получением системного действия | |
| DE69828817D1 (de) | Pharmazeutische aerosolzusammensetzungen | |
| BR0215380A (pt) | Pó micronizado farmacêutico ou nutracêutico de liberação imediata e utilização do mesmo | |
| HUP9800641A2 (hu) | Inhaláló berendezés beklometaszon-dipropionát adagolására mért dózisban | |
| ATE336268T1 (de) | Medizinische aerosolzubereitung | |
| ATE271383T1 (de) | Pulverformulierung zur inhalation | |
| CA2381329A1 (en) | Medicaments | |
| DE60321774D1 (de) | Aerosol-formulierungen von formoterol und mometason | |
| EP1757269A3 (en) | Pulmonary formulation comprising silicon particles | |
| FI956228A0 (fi) | Sisäänhengitykseen tarkoitettuja koostumuksia | |
| SE0002643L (sv) | Inhalationsberedningar innehållande mikropartiklar | |
| HUP0000587A1 (hu) | Takrolimuszt (FK506) tartalmazó gyógyszerkészítmény | |
| HUP9802391A2 (hu) | Inhaláló berendezés szalmeterol adagolására mért dózisban | |
| CY1112978T1 (el) | Αερολυματα που περιεχουν νανοσωματιδιακα φαρμακα | |
| ATE233544T1 (de) | Aerosole als darreichungsform mit cfc-freiem treibmittel | |
| SI1476138T1 (sl) | Formulacije s prirejenim sproščanjem vsaj ene oblike tramadola | |
| MXPA03000442A (es) | Una formulacion medicinal en aerosol. | |
| ATE364381T1 (de) | Formulierungen zur verwendung in inhalationsvorrichtungen | |
| ATE321537T1 (de) | Pharmazeutische zubereitung enthaltend doxazosin | |
| WO2003075977A3 (en) | Agglomerated particles for aerosol drug delivery | |
| ATE343374T1 (de) | Fluticasonpropionat arzneizubereitung | |
| SE9300581D0 (sv) | Komposition foer nasalbehandling | |
| ATE406152T1 (de) | Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |