DE60230894D1 - - Google Patents

Info

Publication number
DE60230894D1
DE60230894D1 DE60230894T DE60230894T DE60230894D1 DE 60230894 D1 DE60230894 D1 DE 60230894D1 DE 60230894 T DE60230894 T DE 60230894T DE 60230894 T DE60230894 T DE 60230894T DE 60230894 D1 DE60230894 D1 DE 60230894D1
Authority
DE
Germany
Prior art keywords
attached
facet
abrading
skin
handle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230894T
Other languages
German (de)
English (en)
Inventor
John A Mikszta
Ronald J Pettis
Jason Alarcon
John M Brittingham
John Dekker Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE60230894D1 publication Critical patent/DE60230894D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/54—Chiropodists' instruments, e.g. pedicure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Coating Apparatus (AREA)
DE60230894T 2001-10-29 2002-10-29 Expired - Lifetime DE60230894D1 (https=)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33071301P 2001-10-29 2001-10-29
US33316201P 2001-11-27 2001-11-27
PCT/US2002/034504 WO2003051284A2 (en) 2001-10-29 2002-10-29 Method and device for the delivery of a substance

Publications (1)

Publication Number Publication Date
DE60230894D1 true DE60230894D1 (https=) 2009-03-05

Family

ID=26987410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230894T Expired - Lifetime DE60230894D1 (https=) 2001-10-29 2002-10-29

Country Status (12)

Country Link
US (1) US20030093040A1 (https=)
EP (1) EP1439870B1 (https=)
JP (1) JP2005511248A (https=)
CN (1) CN1662266A (https=)
AT (1) ATE420676T1 (https=)
AU (1) AU2002365144A1 (https=)
BR (1) BR0213686A (https=)
CA (1) CA2464994A1 (https=)
DE (1) DE60230894D1 (https=)
ES (1) ES2319625T3 (https=)
MX (1) MXPA04003953A (https=)
WO (1) WO2003051284A2 (https=)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
CN1253220C (zh) * 2001-06-29 2006-04-26 贝克顿迪肯森公司 通过微管在真皮内输入疫苗和基因治疗剂
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
BRPI0307434B8 (pt) * 2002-02-04 2021-06-22 Becton Dickinson Co dispositivo para aplicar ou retirar uma substância através da pele.
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
US7422567B2 (en) * 2002-08-29 2008-09-09 Becton, Dickinson And Company Microabrader with controlled abrasion features
KR20060038407A (ko) 2003-06-30 2006-05-03 알자 코포레이션 비휘발성 반대이온을 포함하는 코팅된 미세돌출부용 제제
US8961477B2 (en) * 2003-08-25 2015-02-24 3M Innovative Properties Company Delivery of immune response modifier compounds
KR20070010115A (ko) * 2003-11-13 2007-01-22 알자 코포레이션 경피전달용 조성물 및 장치
US20070191761A1 (en) * 2004-02-23 2007-08-16 3M Innovative Properties Company Method of molding for microneedle arrays
SE0402100D0 (sv) * 2004-08-30 2004-08-30 Bonsens Ab Molded micro-needles
DK2995331T3 (da) 2004-09-10 2019-01-02 Becton Dickinson Co Rekonstitutonsinfusionsindretning og fremgangsmåde til rekostituering af et medikament
US20070053965A1 (en) * 2005-02-25 2007-03-08 Gruenenthal Gmbh Kit comprising a plaster, optionally containing an active substance, and an agent that at least partially reduces skin irritation
EP2258441A3 (en) * 2005-09-02 2011-09-21 Intercell USA, Inc. Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs
DE102005044737A1 (de) * 2005-09-19 2007-03-29 Braun Gmbh Verfahren zum Entfernen von Haaren, Haarentfernungsgerät und Aufsatz hierfür
CA2629193C (en) 2005-11-18 2016-03-29 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US8554317B2 (en) * 2005-11-30 2013-10-08 3M Innovative Properties Company Microneedle arrays and methods of use thereof
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
WO2007080596A2 (en) * 2006-01-12 2007-07-19 Nano Pass Technologies Ltd. Device for superficial abrasive treatment of the skin
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US7794732B2 (en) * 2006-05-12 2010-09-14 Oklahoma Medical Research Foundation Anthrax compositions and methods of use and production
EP2119469B1 (en) * 2007-02-06 2014-05-14 Hisamitsu Pharmaceutical Co., Inc. Microneedle device for diagnosis of allergy
WO2009088884A1 (en) 2008-01-04 2009-07-16 Edge Systems Corporation Apparatus and method for treating the skin
US8814836B2 (en) 2008-01-29 2014-08-26 Edge Systems Llc Devices, systems and methods for treating the skin using time-release substances
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
EP2305292A4 (en) 2008-08-01 2013-02-20 So Pharmaceutical Corp TRANSDERMAL IMMUNIZER OF S / O TYPE
WO2011005894A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
GB201007207D0 (en) * 2010-04-29 2010-06-16 Univ Cork Method
JP5788019B2 (ja) * 2011-11-18 2015-09-30 南部化成株式会社 経皮投薬装置
US9044582B2 (en) * 2012-06-26 2015-06-02 Franklin J. Chang Apparatus and method for transdermal fluid delivery
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
EP3437575B1 (en) 2013-03-15 2021-04-21 Edge Systems LLC Devices and systems for treating the skin
US10194935B2 (en) * 2013-12-31 2019-02-05 L'oreal Shear-induced dermal infusion
CN115154882A (zh) * 2014-03-26 2022-10-11 纳诺麦德皮肤护理公司 物质传送装置及头部
WO2016096444A1 (en) * 2014-12-18 2016-06-23 Koninklijke Philips N.V. Microdermabrasion device
WO2016106396A1 (en) 2014-12-23 2016-06-30 Edge Systems Llc Devices and methods for treating the skin using a rollerball or a wicking member
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP4197517A1 (en) 2015-07-08 2023-06-21 HydraFacial LLC Devices, systems and methods for promoting hair growth
CN108056845A (zh) * 2017-12-15 2018-05-22 深圳清华大学研究院 一种侧路腰椎椎间融合器
AU2019346549B2 (en) * 2018-09-24 2024-09-12 Krystal Biotech, Inc. Compositions and methods for the treatment of Netherton Syndrome
US11291474B2 (en) 2020-01-06 2022-04-05 Ed F. Nicolas Skin treatment tool applicator tip
EP4294446A4 (en) * 2021-02-18 2024-12-04 Agonex Biopharmaceuticals, Inc. SYSTEMS, DEVICES AND FORMULATIONS FOR THE ADMINISTRATION OF FRACTIONATED HISTAMINE
CA3231401A1 (en) 2021-09-10 2023-03-16 Hydrafacial Llc Devices, systems and methods for treating the skin
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
USD1065551S1 (en) 2021-09-10 2025-03-04 Hydrafacial Llc Skin treatment device
USD1116120S1 (en) 2021-10-11 2026-03-03 Hydrafacial Llc Skin treatment device
USD1042807S1 (en) 2021-10-11 2024-09-17 Hydrafacial Llc Skin treatment tip
USD1112778S1 (en) 2022-03-04 2026-02-10 Hydrafacial Llc Light therapy device for skin care
GB2622416B (en) * 2022-09-15 2025-04-02 Ndm Tech Ltd Skin preparation device
USD1084369S1 (en) 2023-02-10 2025-07-15 Hydrafacial Llc Skin treatment tip
DE102024101897A1 (de) * 2024-01-23 2025-07-24 Gwenaël Bauer Dermabrasionswerkzeug mit auspressbarem Fluidbehälter

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3289670A (en) * 1964-03-09 1966-12-06 Milo Bundy Corp Device for abrading and applying biologicals to the skin of a patient
US3556080A (en) * 1968-04-08 1971-01-19 Lincoln Lab Inc Skin allergy testing device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4270548A (en) * 1979-09-05 1981-06-02 Aller-Screen, Inc. Allergy testing method
FR2474856A1 (fr) * 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
FR2498443B2 (fr) * 1981-01-26 1986-03-28 Merieux Inst Dispositif scarificateur
US4483348A (en) * 1982-03-25 1984-11-20 Nathan Sher Skin testing device
US4597764A (en) * 1983-09-28 1986-07-01 Bruce Black Ossicular replacement prosthesis
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4746515A (en) * 1987-02-26 1988-05-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolaurate
AU614092B2 (en) * 1987-09-11 1991-08-22 Paul Max Grinwald Improved method and apparatus for enhanced drug permeation of skin
TW279133B (https=) * 1990-12-13 1996-06-21 Elan Med Tech
US5273528A (en) * 1992-07-10 1993-12-28 Skeen Mikell L Livestock inoculator
DE4307869C2 (de) * 1993-03-12 1996-04-04 Microparts Gmbh Mikrostrukturkörper und Verfahren zu deren Herstellung
US5679647A (en) * 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5885211A (en) * 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5380337A (en) * 1994-01-24 1995-01-10 Romaine; Richard A. Mesh-type skin biopsy appliance
US5660680A (en) * 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
US5611806A (en) * 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
US5591139A (en) * 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
US6368333B2 (en) * 1994-06-29 2002-04-09 Mattioli Engineering Ltd. V-shaped handpiece for dermabrasion
WO1996037155A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
AU5869796A (en) * 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
US5958589A (en) * 1995-07-07 1999-09-28 The United States Of America As Represented By The Secretary Of Agriculture Starch-based microcellular foams
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5658515A (en) * 1995-09-25 1997-08-19 Lee; Abraham P. Polymer micromold and fabrication process
US6032060A (en) * 1996-01-25 2000-02-29 3M Innovative Properties Company Method for conditioning skin and an electrode by passing electrical energy
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US5919364A (en) * 1996-06-24 1999-07-06 Regents Of The University Of California Microfabricated filter and shell constructed with a permeable membrane
ATE241405T1 (de) * 1996-07-03 2003-06-15 Altea Therapeutics Corp Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5983136A (en) * 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US5910306A (en) * 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
AU6036998A (en) * 1997-01-24 1998-08-18 Regents Of The University Of California, The Apparatus and method for planar laminar mixing
US5928207A (en) * 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
US6077229A (en) * 1997-10-21 2000-06-20 Pitesky; Isadore Allergy testing apparatus
US5999847A (en) * 1997-10-21 1999-12-07 Elstrom; John A. Apparatus and method for delivery of surgical and therapeutic agents
US5931794A (en) * 1997-10-21 1999-08-03 Pitesky; Isadore Allergy testing apparatus
DE69806963T2 (de) * 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US5970998A (en) * 1998-02-27 1999-10-26 The Regents Of The University Of California Microfabricated cantilever ratchet valve, and method for using same
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6106751A (en) * 1998-03-18 2000-08-22 The Regents Of The University Of California Method for fabricating needles via conformal deposition in two-piece molds
US7004933B2 (en) * 1998-05-29 2006-02-28 Light Bioscience L.L.C. Ultrasound enhancement of percutaneous drug absorption
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6162232A (en) * 1999-03-18 2000-12-19 Shadduck; John H. Instruments and techniques for high-velocity fluid abrasion of epidermal layers with skin cooling
US6582442B2 (en) * 2000-02-28 2003-06-24 Dynatronics Corporation Method and system for performing microabrasion
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6331266B1 (en) * 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
MXPA02005765A (es) * 1999-12-10 2003-01-28 Alza Corp Aparato de tratamiento de piel para el suministro de farmaco transdermico sostenido.
AU2088301A (en) * 1999-12-16 2001-06-25 Alza Corporation Device for enhancing transdermal flux of sampled agents
US6706032B2 (en) * 2000-06-08 2004-03-16 Massachusetts Institute Of Technology Localized molecular and ionic transport to and from tissues
ATE416692T1 (de) * 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
AU2002343457A1 (en) * 2001-09-28 2003-04-07 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same

Also Published As

Publication number Publication date
WO2003051284A2 (en) 2003-06-26
EP1439870A4 (en) 2006-03-01
US20030093040A1 (en) 2003-05-15
EP1439870B1 (en) 2009-01-14
CN1662266A (zh) 2005-08-31
JP2005511248A (ja) 2005-04-28
ES2319625T3 (es) 2009-05-11
CA2464994A1 (en) 2003-06-26
WO2003051284A3 (en) 2004-01-29
ATE420676T1 (de) 2009-01-15
MXPA04003953A (es) 2004-06-18
EP1439870A2 (en) 2004-07-28
BR0213686A (pt) 2006-05-23
AU2002365144A1 (en) 2003-06-30

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