DE60228615D1 - Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung - Google Patents
Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindungInfo
- Publication number
- DE60228615D1 DE60228615D1 DE60228615T DE60228615T DE60228615D1 DE 60228615 D1 DE60228615 D1 DE 60228615D1 DE 60228615 T DE60228615 T DE 60228615T DE 60228615 T DE60228615 T DE 60228615T DE 60228615 D1 DE60228615 D1 DE 60228615D1
- Authority
- DE
- Germany
- Prior art keywords
- amid
- compound containing
- ester group
- aerosol compositions
- excipient compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 150000002148 esters Chemical group 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000001412 amines Chemical group 0.000 abstract 2
- 125000004185 ester group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34262301P | 2001-12-21 | 2001-12-21 | |
| PCT/US2002/041251 WO2003059331A2 (en) | 2001-12-21 | 2002-12-20 | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60228615D1 true DE60228615D1 (de) | 2008-10-09 |
Family
ID=23342584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60228615T Expired - Lifetime DE60228615D1 (de) | 2001-12-21 | 2002-12-20 | Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7186402B2 (enExample) |
| EP (1) | EP1455764B1 (enExample) |
| JP (1) | JP2005514440A (enExample) |
| AT (1) | ATE406152T1 (enExample) |
| AU (1) | AU2002364594A1 (enExample) |
| CA (1) | CA2470498A1 (enExample) |
| DE (1) | DE60228615D1 (enExample) |
| WO (1) | WO2003059331A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003059331A2 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
| US20030147814A1 (en) * | 2001-12-21 | 2003-08-07 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
| DE60231428D1 (de) * | 2001-12-21 | 2009-04-16 | 3M Innovative Properties Co | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff |
| US20050123484A1 (en) * | 2003-10-02 | 2005-06-09 | Collegium Pharmaceutical, Inc. | Non-flammable topical anesthetic liquid aerosols |
| US20060188449A1 (en) * | 2003-10-03 | 2006-08-24 | Jane Hirsh | Topical aerosol foams |
| US20050255048A1 (en) * | 2004-05-15 | 2005-11-17 | Collegium Pharmaceutical, Inc. | Sprayable formulations for the treatment of acute inflammatory skin conditions |
| GB0614621D0 (en) | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB0620700D0 (en) | 2006-10-19 | 2006-11-29 | 3M Innovative Properties Co | Metered dose valves and dispensers |
| US8652443B2 (en) * | 2008-02-14 | 2014-02-18 | Precision Dermatology, Inc. | Foamable microemulsion compositions for topical administration |
| GB201118188D0 (en) | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| GB201210580D0 (en) * | 2012-06-14 | 2012-08-01 | 3M Innovative Properties Co | Metered dose dispensing valve |
| GB201221063D0 (en) | 2012-11-23 | 2013-01-09 | 3M Innovative Properties Co | Metered dose dispensing valve |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
| JP3009924B2 (ja) | 1992-12-09 | 2000-02-14 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 安定化医用エアーゾル溶液製剤 |
| CA2156408C (en) * | 1993-03-17 | 2005-02-15 | Daniel C. Duan | Aerosol formulation containing a polyester dispersing aid |
| JPH08507792A (ja) * | 1993-03-17 | 1996-08-20 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | ジオール−二酸から誘導される分散助剤を含むエーロゾル配合物 |
| US5492688A (en) * | 1993-04-28 | 1996-02-20 | The Center For Innovative Technology | Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent |
| DK0731688T3 (da) * | 1993-12-02 | 2003-06-23 | Abbott Lab | Aerosol-lægemiddelformuleringer til anvendelse med CFC-frie drivmidler |
| US5508023A (en) * | 1994-04-11 | 1996-04-16 | The Center For Innovative Technology | Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant |
| US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US5650386A (en) * | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
| US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| US6218353B1 (en) * | 1997-08-27 | 2001-04-17 | Micell Technologies, Inc. | Solid particulate propellant systems and aerosol containers employing the same |
| US6136294C1 (en) * | 1998-09-22 | 2002-09-24 | Aeropharm Technology Inc | Amino acid stabilized medical aerosol formulation |
| DE69904498T2 (de) * | 1998-10-27 | 2003-04-24 | Alcon Laboratories, Inc. | Konservierungsmittel für lokale pharmazeutische zubereitungen enthaltend eine fettsäure/aminosäure enthaltende seife |
| US6258857B1 (en) * | 1999-02-04 | 2001-07-10 | Kyowa Industrial Co., Ltd. | Internal liquid composition contained as internal liquid in a releasing container and releasing container product |
| JP2003535122A (ja) | 2000-06-02 | 2003-11-25 | ザイコス インク． | 生物活性物質のための送達システム |
| DE60231428D1 (de) * | 2001-12-21 | 2009-04-16 | 3M Innovative Properties Co | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff |
| US20030147814A1 (en) * | 2001-12-21 | 2003-08-07 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
| WO2003059331A2 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
-
2002
- 2002-12-20 WO PCT/US2002/041251 patent/WO2003059331A2/en not_active Ceased
- 2002-12-20 DE DE60228615T patent/DE60228615D1/de not_active Expired - Lifetime
- 2002-12-20 AT AT02799975T patent/ATE406152T1/de not_active IP Right Cessation
- 2002-12-20 JP JP2003559494A patent/JP2005514440A/ja not_active Withdrawn
- 2002-12-20 AU AU2002364594A patent/AU2002364594A1/en not_active Abandoned
- 2002-12-20 CA CA002470498A patent/CA2470498A1/en not_active Abandoned
- 2002-12-20 US US10/327,198 patent/US7186402B2/en not_active Expired - Fee Related
- 2002-12-20 EP EP02799975A patent/EP1455764B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE406152T1 (de) | 2008-09-15 |
| JP2005514440A (ja) | 2005-05-19 |
| WO2003059331A2 (en) | 2003-07-24 |
| EP1455764A2 (en) | 2004-09-15 |
| US7186402B2 (en) | 2007-03-06 |
| CA2470498A1 (en) | 2003-07-24 |
| WO2003059331A3 (en) | 2003-11-20 |
| US20030138381A1 (en) | 2003-07-24 |
| AU2002364594A1 (en) | 2003-07-30 |
| EP1455764B1 (en) | 2008-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |