DE60228615D1 - Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung - Google Patents
Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindungInfo
- Publication number
- DE60228615D1 DE60228615D1 DE60228615T DE60228615T DE60228615D1 DE 60228615 D1 DE60228615 D1 DE 60228615D1 DE 60228615 T DE60228615 T DE 60228615T DE 60228615 T DE60228615 T DE 60228615T DE 60228615 D1 DE60228615 D1 DE 60228615D1
- Authority
- DE
- Germany
- Prior art keywords
- amid
- compound containing
- ester group
- aerosol compositions
- excipient compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 150000002148 esters Chemical group 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000001412 amines Chemical group 0.000 abstract 2
- 125000004185 ester group Chemical group 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34262301P | 2001-12-21 | 2001-12-21 | |
| PCT/US2002/041251 WO2003059331A2 (en) | 2001-12-21 | 2002-12-20 | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60228615D1 true DE60228615D1 (de) | 2008-10-09 |
Family
ID=23342584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60228615T Expired - Lifetime DE60228615D1 (de) | 2001-12-21 | 2002-12-20 | Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7186402B2 (enExample) |
| EP (1) | EP1455764B1 (enExample) |
| JP (1) | JP2005514440A (enExample) |
| AT (1) | ATE406152T1 (enExample) |
| AU (1) | AU2002364594A1 (enExample) |
| CA (1) | CA2470498A1 (enExample) |
| DE (1) | DE60228615D1 (enExample) |
| WO (1) | WO2003059331A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1458354A1 (en) * | 2001-12-21 | 2004-09-22 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
| CA2470498A1 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
| EP1458357B1 (en) * | 2001-12-21 | 2009-03-04 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
| WO2005032521A2 (en) * | 2003-10-02 | 2005-04-14 | Collegium Pharmaceutical, Inc. | Non-flammable topical anesthetic liquid aerosols |
| US20060188449A1 (en) * | 2003-10-03 | 2006-08-24 | Jane Hirsh | Topical aerosol foams |
| WO2005115336A2 (en) * | 2004-05-15 | 2005-12-08 | Collegium Pharmaceutical, Inc. | Sprayable formulations for the treatment of acute inflammatory skin conditions |
| GB0614621D0 (en) | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB0620700D0 (en) | 2006-10-19 | 2006-11-29 | 3M Innovative Properties Co | Metered dose valves and dispensers |
| US8652443B2 (en) * | 2008-02-14 | 2014-02-18 | Precision Dermatology, Inc. | Foamable microemulsion compositions for topical administration |
| GB201118188D0 (en) | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| GB201210580D0 (en) | 2012-06-14 | 2012-08-01 | 3M Innovative Properties Co | Metered dose dispensing valve |
| GB201221063D0 (en) | 2012-11-23 | 2013-01-09 | 3M Innovative Properties Co | Metered dose dispensing valve |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225183A (en) | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
| ES2129117T3 (es) | 1992-12-09 | 1999-06-01 | Boehringer Ingelheim Pharma | Formulaciones en disolucion en forma de aerosol medicinales estabilizadas. |
| KR100321649B1 (ko) | 1993-03-17 | 2002-07-22 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | 에스테르,아미드또는머캅토에스테르로부터유도된분산보조제를함유하는에어로졸제제 |
| DE69405719T2 (de) | 1993-03-17 | 1998-01-15 | Minnesota Mining & Mfg | Aerosolzubereitung, enthaltend ein aus einem diol-disäure-derivat abgeleitetes dispergiermittel |
| US5492688A (en) | 1993-04-28 | 1996-02-20 | The Center For Innovative Technology | Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent |
| JPH09506097A (ja) | 1993-12-02 | 1997-06-17 | アボツト・ラボラトリーズ | 非ｃｆｃ噴射剤と共に用いるエアロゾル薬物調剤 |
| US5508023A (en) | 1994-04-11 | 1996-04-16 | The Center For Innovative Technology | Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant |
| US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
| US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| US6218353B1 (en) | 1997-08-27 | 2001-04-17 | Micell Technologies, Inc. | Solid particulate propellant systems and aerosol containers employing the same |
| US6136294C1 (en) * | 1998-09-22 | 2002-09-24 | Aeropharm Technology Inc | Amino acid stabilized medical aerosol formulation |
| BR9914799A (pt) | 1998-10-27 | 2001-07-10 | Alcon Lab Inc | Sistema conservante para composições farmacêuticas administráveis topicamente contendo um sabão de ácido graxo/aminoácido |
| US6258857B1 (en) * | 1999-02-04 | 2001-07-10 | Kyowa Industrial Co., Ltd. | Internal liquid composition contained as internal liquid in a releasing container and releasing container product |
| JP2003535122A (ja) | 2000-06-02 | 2003-11-25 | ザイコス インク． | 生物活性物質のための送達システム |
| EP1458354A1 (en) * | 2001-12-21 | 2004-09-22 | 3M Innovative Properties Company | Medicinal aerosol formulations comprising ion pair complexes |
| EP1458357B1 (en) * | 2001-12-21 | 2009-03-04 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
| CA2470498A1 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with an amide and/or ester containing excipient compound |
-
2002
- 2002-12-20 CA CA002470498A patent/CA2470498A1/en not_active Abandoned
- 2002-12-20 AU AU2002364594A patent/AU2002364594A1/en not_active Abandoned
- 2002-12-20 AT AT02799975T patent/ATE406152T1/de not_active IP Right Cessation
- 2002-12-20 EP EP02799975A patent/EP1455764B1/en not_active Expired - Lifetime
- 2002-12-20 US US10/327,198 patent/US7186402B2/en not_active Expired - Fee Related
- 2002-12-20 WO PCT/US2002/041251 patent/WO2003059331A2/en not_active Ceased
- 2002-12-20 JP JP2003559494A patent/JP2005514440A/ja not_active Withdrawn
- 2002-12-20 DE DE60228615T patent/DE60228615D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002364594A1 (en) | 2003-07-30 |
| US7186402B2 (en) | 2007-03-06 |
| WO2003059331A2 (en) | 2003-07-24 |
| ATE406152T1 (de) | 2008-09-15 |
| CA2470498A1 (en) | 2003-07-24 |
| EP1455764A2 (en) | 2004-09-15 |
| JP2005514440A (ja) | 2005-05-19 |
| US20030138381A1 (en) | 2003-07-24 |
| WO2003059331A3 (en) | 2003-11-20 |
| EP1455764B1 (en) | 2008-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200401006A1 (ru) | Аэрозольные препараты для внутрилёгочного введения лекарств с получением системного действия | |
| DE69932835D1 (de) | Medizinische aerosolzubereitung | |
| ATE406152T1 (de) | Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung | |
| ATE271383T1 (de) | Pulverformulierung zur inhalation | |
| BR0214254A (pt) | Pó filmogênio micronizado e composição farmacêutica, cosmética ou neutracêutica | |
| BR9909394A (pt) | Composição de aerossol, composição farmacêutica, recipiente, dispositivo de inalação, processo para preparar uma composição de aerossol, mistura de um primeiro material particulado, e, processo para administrar um medicamento particulado | |
| NO20043913L (no) | Blandinger med modifisert frigjoring av i det minste en form av tramadol | |
| DE69432025D1 (de) | Formulierungen mit verzögerter freisetzung zur abgabe von metoprolol über 24 stunden | |
| ATE293995T1 (de) | Pharmazeutische zusammensetzungen, die wirkstoffabsorptionsfördernde verbindungen enthalten | |
| DE69233150D1 (de) | Fluorchlorkohlenwasserstoffreie Aerosolformulierungen | |
| FR2764889B1 (fr) | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant | |
| BR9307431A (pt) | Composição à base de água formadora de pelìcula curável | |
| FR2784678B1 (fr) | Nouveaux derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant | |
| CA2416403A1 (en) | A medicinal aerosol formulation | |
| EA199900991A1 (ru) | Медицинские аэрозольные препараты | |
| ATE202931T1 (de) | Taxanderivate enthaltende arzneizubereitungen | |
| KR860005636A (ko) | 활성성분으로 스페르구알린(Spergualin)을 함유하는 주사제 조성물과 그 제조방법. | |
| SE9300581D0 (sv) | Komposition foer nasalbehandling | |
| ATE424186T1 (de) | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff | |
| FR2740134B1 (fr) | Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant | |
| DE69323921D1 (de) | Mutante des Respiratory-syncytial-Virus (RS-Virus) und eine eine solche Mutante enthaltende pharmazeutische Zusammensetzung | |
| IL79816A0 (en) | Pharmaceutical composition comprising a drug-polymer matrix | |
| EA200000664A1 (ru) | Фармацевтические композиции, содержащие микронизированные бициклические лекарственные средства | |
| ID21546A (id) | Turunan-turunan amida baru dan komposisi-komposisi obat darinya | |
| DK0972519T3 (da) | Immuntolerance-inducere |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |