DE60226012D1 - Geschmacksmaskierte pharmazeutische formulierungen - Google Patents

Geschmacksmaskierte pharmazeutische formulierungen

Info

Publication number
DE60226012D1
DE60226012D1 DE60226012T DE60226012T DE60226012D1 DE 60226012 D1 DE60226012 D1 DE 60226012D1 DE 60226012 T DE60226012 T DE 60226012T DE 60226012 T DE60226012 T DE 60226012T DE 60226012 D1 DE60226012 D1 DE 60226012D1
Authority
DE
Germany
Prior art keywords
taste
masked pharmaceutical
pharmaceutical formulations
microcapsule
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60226012T
Other languages
English (en)
Other versions
DE60226012T2 (de
Inventor
Stephen A Ulrich
Karen R Zimm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of DE60226012D1 publication Critical patent/DE60226012D1/de
Application granted granted Critical
Publication of DE60226012T2 publication Critical patent/DE60226012T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60226012T 2001-03-05 2002-02-26 Geschmacksmaskierte pharmazeutische formulierungen Expired - Fee Related DE60226012T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27347301P 2001-03-05 2001-03-05
US273473P 2001-03-05
PCT/US2002/005795 WO2002069939A2 (en) 2001-03-05 2002-02-26 Taste masked pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE60226012D1 true DE60226012D1 (de) 2008-05-21
DE60226012T2 DE60226012T2 (de) 2009-05-14

Family

ID=23044085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60226012T Expired - Fee Related DE60226012T2 (de) 2001-03-05 2002-02-26 Geschmacksmaskierte pharmazeutische formulierungen

Country Status (12)

Country Link
US (1) US6767557B2 (de)
EP (1) EP1370247B1 (de)
JP (1) JP2004520420A (de)
AT (1) ATE391496T1 (de)
AU (1) AU2002254036A1 (de)
BR (1) BR0207932A (de)
CA (1) CA2440069A1 (de)
DE (1) DE60226012T2 (de)
HK (1) HK1058482A1 (de)
MX (1) MXPA03008057A (de)
MY (1) MY129317A (de)
WO (1) WO2002069939A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2440412A1 (en) * 2001-03-05 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Taste masked liquid pharmaceutical compositions
FR2821747B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Suspension de telithromycine a gout masque
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
MXPA04009979A (es) * 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxicilina.
CA2480826C (fr) * 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
CA2503290C (en) 2003-03-10 2012-12-04 Altana Pharma Ag Novel process for the preparation of roflumilast
WO2005013944A1 (en) * 2003-08-11 2005-02-17 Merck Frosst Canada Ltd. Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US20060013834A1 (en) * 2004-02-24 2006-01-19 Medicis Pediatrics, Inc. Room temperature stable aqueous liquid pharmaceutical composition
US20060127479A1 (en) * 2004-10-08 2006-06-15 Natrajan Kumaraperumal Solvent free taste masked pharmaceutical compositions
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US20060216355A1 (en) * 2005-03-28 2006-09-28 Donald Spector Encapsulated pharmaceuticals in a medium having non-encapsulated flavoring agents
US9023382B2 (en) * 2005-06-08 2015-05-05 Basf Corporation Medicament carrier composition and method of forming a film therefrom
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
US20070281014A1 (en) * 2006-06-01 2007-12-06 Cima Labs, Inc. Prednisolone salt formulations
US8637076B2 (en) * 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
US8304226B2 (en) * 2006-08-22 2012-11-06 Carl Miller Quality of life of hepatitis C patients with a formulation for administration to the oral mucosa including freeze dried lysate of selected Lactobacillus or Bifidobacterium species and N-acetyl D-glucosamine
US8007783B2 (en) * 2006-08-22 2011-08-30 Carl Miller Quality of life for hepatitis C patients with a formulation for administration to the oral mucosa including Lactobacillus delbrueckii subsp. bulgaricus and N-acetyl D-glucosamine
WO2008098586A1 (en) * 2007-02-13 2008-08-21 Dafra Pharma N.V. Pharmaceutical carrier composition and pharmaceutical composition
JP2010530408A (ja) * 2007-06-18 2010-09-09 ドルハイ クリニカ エゲースセーギュジ ケーエフティー． 殺生物性カプセル、それらを含む製剤、及び該製剤を含む衛生パッド
US20090065225A1 (en) * 2007-09-07 2009-03-12 Black & Decker Inc. Switchable anti-lock control
BRPI1009121A2 (pt) * 2009-03-04 2018-06-19 Orexo Ab formulações resistentes a abuso
CN102421419B (zh) 2009-05-08 2016-05-04 奥瑞克索股份公司 用于持续药物传递的包含地聚合物粘合剂的组合物
US20110236494A1 (en) * 2010-03-04 2011-09-29 Ranbaxy Laboratories Limited Ciprofloxacin oral suspension
PT2558079T (pt) 2010-04-12 2019-09-05 S Zhaveri Pharmakem Pvt Ltd Composição de xarope seco de ciprofloxacina
WO2012032337A2 (en) 2010-09-07 2012-03-15 Orexo Ab A transdermal drug administration device
JP5976657B2 (ja) * 2011-09-30 2016-08-24 持田製薬株式会社 易服用性固形製剤
SG11201402650RA (en) 2012-01-16 2014-06-27 Elizabeth Mckenna Compositions and methods for the treatment of hepatic diseases and disorders
BR112015006264A2 (pt) 2012-09-21 2017-07-04 Mckenna Elizabeth composições de oligonucleotídeos cpg ocorrendo naturalmente e suas aplicações terapêuticas
WO2014144661A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Compny Rapidly dispersible dosage form of topiramate
ES2761265T3 (es) 2013-03-15 2020-05-19 Aprecia Pharmaceuticals LLC Forma de dosificación de oxcarbazepina rápidamente dispersable
US10098964B2 (en) 2015-03-12 2018-10-16 The Board Of Trustees Of The University Of Illinois Inclusion complexes and methods for making the same
JP6294400B2 (ja) * 2016-07-19 2018-03-14 持田製薬株式会社 易服用性固形製剤
EP3883546A1 (de) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Orale topiramat-suspensionsformulierungen mit verlängerter lagerstabilität und verbesserter bioverfügbarkeit
EP3984529A4 (de) * 2019-06-17 2022-08-10 Towa Pharmaceutical Co., Ltd. Maskierungsteilchen mit zeitgesteuerter elution und diese enthaltende orale pharmazeutische zusammensetzung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5599556A (en) 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
DE4200821A1 (de) 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
DE19631084A1 (de) * 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
US6328994B1 (en) * 1998-05-18 2001-12-11 Takeda Chemical Industries, Ltd. Orally disintegrable tablets
BR9912533A (pt) * 1998-07-31 2002-02-13 Otsuka Pharma Co Ltd Composição farmacêutica tendo sabor melhorado
AU4943000A (en) * 1999-06-11 2001-01-02 Ranbaxy Laboratories Limited Taste masked compositions
IN192159B (de) * 2000-05-15 2004-02-28 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
BR0207932A (pt) 2004-03-02
MXPA03008057A (es) 2004-10-15
HK1058482A1 (en) 2004-05-21
JP2004520420A (ja) 2004-07-08
CA2440069A1 (en) 2002-09-12
ATE391496T1 (de) 2008-04-15
EP1370247A2 (de) 2003-12-17
WO2002069939A3 (en) 2003-03-13
US6767557B2 (en) 2004-07-27
US20020197327A1 (en) 2002-12-26
EP1370247B1 (de) 2008-04-09
DE60226012T2 (de) 2009-05-14
WO2002069939A2 (en) 2002-09-12
MY129317A (en) 2007-03-30
AU2002254036A1 (en) 2002-09-19

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC., TI, US

8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee