DE60226012D1 - Geschmacksmaskierte pharmazeutische formulierungen - Google Patents

Geschmacksmaskierte pharmazeutische formulierungen

Info

Publication number
DE60226012D1
DE60226012D1 DE60226012T DE60226012T DE60226012D1 DE 60226012 D1 DE60226012 D1 DE 60226012D1 DE 60226012 T DE60226012 T DE 60226012T DE 60226012 T DE60226012 T DE 60226012T DE 60226012 D1 DE60226012 D1 DE 60226012D1
Authority
DE
Germany
Prior art keywords
taste
masked pharmaceutical
pharmaceutical formulations
microcapsule
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60226012T
Other languages
English (en)
Other versions
DE60226012T2 (de
Inventor
Stephen A Ulrich
Karen R Zimm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Application granted granted Critical
Publication of DE60226012D1 publication Critical patent/DE60226012D1/de
Publication of DE60226012T2 publication Critical patent/DE60226012T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60226012T 2001-03-05 2002-02-26 Geschmacksmaskierte pharmazeutische formulierungen Expired - Fee Related DE60226012T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27347301P 2001-03-05 2001-03-05
US273473P 2001-03-05
PCT/US2002/005795 WO2002069939A2 (en) 2001-03-05 2002-02-26 Taste masked pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE60226012D1 true DE60226012D1 (de) 2008-05-21
DE60226012T2 DE60226012T2 (de) 2009-05-14

Family

ID=23044085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60226012T Expired - Fee Related DE60226012T2 (de) 2001-03-05 2002-02-26 Geschmacksmaskierte pharmazeutische formulierungen

Country Status (12)

Country Link
US (1) US6767557B2 (de)
EP (1) EP1370247B1 (de)
JP (1) JP2004520420A (de)
AT (1) ATE391496T1 (de)
AU (1) AU2002254036A1 (de)
BR (1) BR0207932A (de)
CA (1) CA2440069A1 (de)
DE (1) DE60226012T2 (de)
HK (1) HK1058482A1 (de)
MX (1) MXPA03008057A (de)
MY (1) MY129317A (de)
WO (1) WO2002069939A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0207930A (pt) * 2001-03-05 2004-03-02 Ortho Mcneil Pharm Inc Composições farmacêuticas lìquidas com sabor mascarado
FR2821747B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Suspension de telithromycine a gout masque
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1492511B3 (de) * 2002-04-09 2012-05-02 Flamel Technologies Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
CN100577164C (zh) * 2002-04-09 2010-01-06 弗拉梅技术公司 可改进释放阿莫西林的微囊含水混悬液形式的口服药物制剂
MXPA04008070A (es) 2003-03-10 2004-11-26 Altana Pharma Ag Novedoso proceso para la preparacion de roflumilasto.
US20060228410A1 (en) * 2003-08-11 2006-10-12 Hubert Dumont Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US20060013834A1 (en) * 2004-02-24 2006-01-19 Medicis Pediatrics, Inc. Room temperature stable aqueous liquid pharmaceutical composition
US20060127479A1 (en) * 2004-10-08 2006-06-15 Natrajan Kumaraperumal Solvent free taste masked pharmaceutical compositions
JP5383183B2 (ja) 2005-03-16 2014-01-08 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング ロフルミラストを含有する矯味された剤形
US20060216355A1 (en) * 2005-03-28 2006-09-28 Donald Spector Encapsulated pharmaceuticals in a medium having non-encapsulated flavoring agents
US9023382B2 (en) * 2005-06-08 2015-05-05 Basf Corporation Medicament carrier composition and method of forming a film therefrom
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
US20070281014A1 (en) * 2006-06-01 2007-12-06 Cima Labs, Inc. Prednisolone salt formulations
US8637076B2 (en) * 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
US8304226B2 (en) * 2006-08-22 2012-11-06 Carl Miller Quality of life of hepatitis C patients with a formulation for administration to the oral mucosa including freeze dried lysate of selected Lactobacillus or Bifidobacterium species and N-acetyl D-glucosamine
US8007783B2 (en) * 2006-08-22 2011-08-30 Carl Miller Quality of life for hepatitis C patients with a formulation for administration to the oral mucosa including Lactobacillus delbrueckii subsp. bulgaricus and N-acetyl D-glucosamine
WO2008098586A1 (en) * 2007-02-13 2008-08-21 Dafra Pharma N.V. Pharmaceutical carrier composition and pharmaceutical composition
EP2167052B1 (de) * 2007-06-18 2015-04-01 Dolhay Klinika Egészségügyi KFT. Biozid-kapseln, diese enthaltende zubereitung und die zubereitung umfassende hygienebinde
US20090065225A1 (en) * 2007-09-07 2009-03-12 Black & Decker Inc. Switchable anti-lock control
NZ594513A (en) * 2009-03-04 2013-10-25 Orexo Ab Abuse resistant formulation
EP2427177B1 (de) 2009-05-08 2018-03-28 Emplicure AB Zusammensetzung mit verzögerter wirkstofffreisetzung enthaltend ein geopolymerisches bindemittel
US20110236494A1 (en) * 2010-03-04 2011-09-29 Ranbaxy Laboratories Limited Ciprofloxacin oral suspension
AU2010351281B2 (en) 2010-04-12 2014-03-20 S. Zhaveri Pharmakem Pvt. Ltd. Ciprofloxacin dry syrup composition
CA2809927C (en) 2010-09-07 2019-08-20 Orexo Ab A transdermal drug administration device
EP2762167A4 (de) 2011-09-30 2015-12-09 Mochida Pharm Co Ltd Einfach einnehmbares feststoffpräparat
KR20200106088A (ko) 2012-01-16 2020-09-10 엘라자베스 맥켄나 간 질환들 및 장애들의 치료를 위한 조성물들 및 방법들
JP2015535829A (ja) 2012-09-21 2015-12-17 マッケーナ、エリザベス 天然に存在するＣｐＧオリゴヌクレオチド組成物およびその治療的適用
CA2906107C (en) 2013-03-15 2021-08-24 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of oxcarbazepine
WO2014144661A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Compny Rapidly dispersible dosage form of topiramate
US10098964B2 (en) 2015-03-12 2018-10-16 The Board Of Trustees Of The University Of Illinois Inclusion complexes and methods for making the same
JP6294400B2 (ja) * 2016-07-19 2018-03-14 持田製薬株式会社 易服用性固形製剤
US20220016074A1 (en) 2018-11-21 2022-01-20 Rosemont Pharmaceuticals Limited Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
WO2020255837A1 (ja) * 2019-06-17 2020-12-24 東和薬品株式会社 時限式溶出マスキング粒子およびそれを含有する経口医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5599556A (en) 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
DE4200821A1 (de) 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
DE19631084A1 (de) * 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
CA2323680C (en) * 1998-05-18 2007-05-22 Takeda Chemical Industries, Ltd. Orally disintegrable tablets
CA2338996A1 (en) 1998-07-31 2000-02-10 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition having improved taste
PT1194124E (pt) 1999-06-11 2004-02-27 Ranbaxy Lab Ltd Composicoes de sabor mascarado
IN192159B (de) 2000-05-15 2004-02-28 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
JP2004520420A (ja) 2004-07-08
MY129317A (en) 2007-03-30
HK1058482A1 (en) 2004-05-21
AU2002254036A1 (en) 2002-09-19
CA2440069A1 (en) 2002-09-12
US6767557B2 (en) 2004-07-27
US20020197327A1 (en) 2002-12-26
WO2002069939A3 (en) 2003-03-13
DE60226012T2 (de) 2009-05-14
MXPA03008057A (es) 2004-10-15
ATE391496T1 (de) 2008-04-15
EP1370247B1 (de) 2008-04-09
EP1370247A2 (de) 2003-12-17
WO2002069939A2 (en) 2002-09-12
BR0207932A (pt) 2004-03-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC., TI, US

8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee