DE60213232D1 - Gezielte freisetzung von arzneimitteln zur behandlung von virusinfektionen - Google Patents
Gezielte freisetzung von arzneimitteln zur behandlung von virusinfektionenInfo
- Publication number
- DE60213232D1 DE60213232D1 DE60213232T DE60213232T DE60213232D1 DE 60213232 D1 DE60213232 D1 DE 60213232D1 DE 60213232 T DE60213232 T DE 60213232T DE 60213232 T DE60213232 T DE 60213232T DE 60213232 D1 DE60213232 D1 DE 60213232D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- medicaments
- virus infections
- targeted release
- viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/644—Transferrin, e.g. a lactoferrin or ovotransferrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29066801P | 2001-05-15 | 2001-05-15 | |
US290668P | 2001-05-15 | ||
US35539402P | 2002-02-08 | 2002-02-08 | |
US355394P | 2002-02-08 | ||
PCT/US2002/011892 WO2002092116A1 (en) | 2001-05-15 | 2002-05-15 | Targeted delivery of drugs for the treatment of viral infections |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60213232D1 true DE60213232D1 (de) | 2006-08-31 |
DE60213232T2 DE60213232T2 (de) | 2007-07-26 |
Family
ID=26966345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60213232T Expired - Lifetime DE60213232T2 (de) | 2001-05-15 | 2002-05-15 | Gezielte freisetzung von arzneimitteln zur behandlung von virusinfektionen |
Country Status (9)
Country | Link |
---|---|
US (1) | US8183208B2 (de) |
EP (1) | EP1395273B1 (de) |
JP (1) | JP2004537515A (de) |
CN (1) | CN100372566C (de) |
AT (1) | ATE333288T1 (de) |
CA (1) | CA2447335C (de) |
DE (1) | DE60213232T2 (de) |
PL (1) | PL367244A1 (de) |
WO (1) | WO2002092116A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1395273B1 (de) | 2001-05-15 | 2006-07-19 | Faulk Pharmaceuticals, Inc. | Gezielte freisetzung von arzneimitteln zur behandlung von virusinfektionen |
WO2002094271A1 (en) * | 2001-05-15 | 2002-11-28 | Faulk Pharmaceuticals, Inc. | Targeted delivery of bioaffecting compounds for the treatment of cancer |
PL366637A1 (en) * | 2001-05-16 | 2005-02-07 | Faulk Pharmaceuticals, Inc. | Targeted delivery of drugs for the treatment of parasitic infections |
CA2869088A1 (en) * | 2002-02-07 | 2003-08-14 | Massachusetts Institute Of Technology | Anti-pathogen treatments |
WO2012138911A2 (en) * | 2011-04-05 | 2012-10-11 | The Administrators Of The Tulane Educational Fund | Conjugates of anti-hiv drugs and somatostatin analogs |
EP4005600A1 (de) * | 2012-04-26 | 2022-06-01 | Yale University | Gegen hiv gerichtete zytotoxische wirkstoffe freisetzende moleküle (cdm-hs), zytotoxische wirkung gegen das menschliche immunschwächevirus und verfahren zur verwendung |
CN107304424B (zh) * | 2016-05-23 | 2019-05-10 | 成都福际生物技术有限公司 | 改造的转铁蛋白dna结合域、重组dna聚合酶及制备方法 |
US20180236098A1 (en) * | 2016-08-12 | 2018-08-23 | L.E.A.F. Holdings Group Llc | Alpha and gamma-d polyglutamated antifolates and uses thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2116979B (en) | 1982-02-25 | 1985-05-15 | Ward Page Faulk | Conjugates of proteins with anti-tumour agents |
US5108987A (en) * | 1982-02-25 | 1992-04-28 | Faulk Ward P | Conjugates of proteins with anti-tumor agents |
GB8519457D0 (en) | 1985-08-02 | 1985-09-11 | Faulk Ward Page | Tumour imaging agents |
IN165717B (de) | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
FI102355B1 (fi) * | 1988-02-11 | 1998-11-30 | Bristol Myers Squibb Co | Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi |
US5688488A (en) | 1989-04-03 | 1997-11-18 | Purdue Research Foundation | Composition and method for tumor imaging |
US5208323A (en) * | 1989-08-10 | 1993-05-04 | Universite Laval | Coupling of an anti-tumor to an antibody using glutaraldehyde preactivated anti-tumor agent |
US5238940A (en) | 1990-03-22 | 1993-08-24 | Quadra Logic Technologies Inc. | Compositions for photodynamic therapy |
US5268165A (en) | 1990-10-16 | 1993-12-07 | Biomedical Frontiers, Inc. | Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging |
US5326778A (en) | 1992-03-03 | 1994-07-05 | Research Corporation Technologies, Inc. | Conjugates of biotin and deferoxamine for radioimmunoimaging and radioimmunotherapy |
DE4435087A1 (de) | 1994-09-30 | 1996-04-04 | Deutsches Krebsforsch | Konjugat zur Behandlung von Infektions-, Autoimmun- und Hauterkrankungen |
US6066319A (en) * | 1996-04-30 | 2000-05-23 | President And Fellows Of Harvard College | Drug delivery using terminal complement components |
US5919643A (en) * | 1996-06-11 | 1999-07-06 | Advanced Research & Technology Institute | Methods and compositions for the use of apurinic/apyrimidinic endonucleases |
DE19636889A1 (de) | 1996-09-11 | 1998-03-12 | Felix Dr Kratz | Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel |
WO2000033884A1 (en) * | 1998-12-04 | 2000-06-15 | Oregon Health Sciences University | Conjugates of lipids and antimicrobial or antineoplastic drugs |
GB9908195D0 (en) * | 1999-04-09 | 1999-06-02 | Microbiological Res Authority | Treatment of intracellular infection |
AUPQ014699A0 (en) | 1999-05-04 | 1999-05-27 | Access Pharmaceuticals Australia Pty Limited | Amplification of folate-mediated targeting to tumor cells using nanoparticles |
JP2004501171A (ja) | 2000-06-28 | 2004-01-15 | フォーク ワード ページ | A)臓器が移植された患者における活性化されたリンパ球への、b)放射線療法を受ける患者における、癌細胞への放射線増感剤としての、c)癌の診断および治療における薬物担体としてのビタミン結合タンパク質中の、細胞毒の標的指向型送達 |
US20020137901A1 (en) | 2001-01-22 | 2002-09-26 | Cavanaugh Philip Gerard | Synthesis, and photodynamic therapy-mediated anti-cancer, and other uses of chlorin e6-transferrin |
US6548531B2 (en) * | 2001-02-09 | 2003-04-15 | Hoffmann-La Roche Inc. | Method for cancer therapy |
US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
FR2824563B1 (fr) | 2001-05-10 | 2004-12-03 | Bio Merieux | Particules composites, conjugues derives, procede de preparation et applications |
EP1395273B1 (de) | 2001-05-15 | 2006-07-19 | Faulk Pharmaceuticals, Inc. | Gezielte freisetzung von arzneimitteln zur behandlung von virusinfektionen |
WO2002094271A1 (en) * | 2001-05-15 | 2002-11-28 | Faulk Pharmaceuticals, Inc. | Targeted delivery of bioaffecting compounds for the treatment of cancer |
PL373511A1 (en) * | 2001-05-15 | 2005-09-05 | Faulk Pharmaceuticals, Inc. | Substantially homogeneous bio-affecting material having a pre-determined ratio of bioaffecting component to cell targeting component, the method for making such a material and the method of its use |
PL366637A1 (en) | 2001-05-16 | 2005-02-07 | Faulk Pharmaceuticals, Inc. | Targeted delivery of drugs for the treatment of parasitic infections |
US20040220086A1 (en) | 2001-10-17 | 2004-11-04 | Faulk W. Page | Methods and materials for targeting and affecting selected cells |
-
2002
- 2002-05-15 EP EP02736575A patent/EP1395273B1/de not_active Expired - Lifetime
- 2002-05-15 DE DE60213232T patent/DE60213232T2/de not_active Expired - Lifetime
- 2002-05-15 CN CNB028142411A patent/CN100372566C/zh not_active Expired - Fee Related
- 2002-05-15 JP JP2002589033A patent/JP2004537515A/ja active Pending
- 2002-05-15 PL PL02367244A patent/PL367244A1/xx not_active Application Discontinuation
- 2002-05-15 CA CA2447335A patent/CA2447335C/en not_active Expired - Fee Related
- 2002-05-15 AT AT02736575T patent/ATE333288T1/de not_active IP Right Cessation
- 2002-05-15 WO PCT/US2002/011892 patent/WO2002092116A1/en active IP Right Grant
-
2008
- 2008-01-03 US US11/968,904 patent/US8183208B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1395273A4 (de) | 2004-08-18 |
JP2004537515A (ja) | 2004-12-16 |
CA2447335C (en) | 2011-01-04 |
CN100372566C (zh) | 2008-03-05 |
CA2447335A1 (en) | 2002-11-21 |
US20080103094A1 (en) | 2008-05-01 |
EP1395273A1 (de) | 2004-03-10 |
EP1395273B1 (de) | 2006-07-19 |
WO2002092116A1 (en) | 2002-11-21 |
CN1529612A (zh) | 2004-09-15 |
DE60213232T2 (de) | 2007-07-26 |
US8183208B2 (en) | 2012-05-22 |
ATE333288T1 (de) | 2006-08-15 |
PL367244A1 (en) | 2005-02-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: VOSSIUS & PARTNER, 81675 MUENCHEN |