DE60212424D1 - Radiopharmazeutishes mittel zur behandlung von krebs im frühstadium - Google Patents
Radiopharmazeutishes mittel zur behandlung von krebs im frühstadiumInfo
- Publication number
- DE60212424D1 DE60212424D1 DE60212424T DE60212424T DE60212424D1 DE 60212424 D1 DE60212424 D1 DE 60212424D1 DE 60212424 T DE60212424 T DE 60212424T DE 60212424 T DE60212424 T DE 60212424T DE 60212424 D1 DE60212424 D1 DE 60212424D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- radiopharmaceutic
- cancer
- agent
- stadium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35559801P | 2001-10-22 | 2001-10-22 | |
| US355598P | 2001-10-22 | ||
| PCT/US2002/033918 WO2003035114A1 (en) | 2001-10-22 | 2002-10-22 | Radiopharmaceutical agent for the treatment of early stage cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60212424D1 true DE60212424D1 (de) | 2006-07-27 |
| DE60212424T2 DE60212424T2 (de) | 2006-10-12 |
Family
ID=23398047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60212424T Expired - Fee Related DE60212424T2 (de) | 2001-10-22 | 2002-10-22 | Radiopharmazeutisches mittel zur behandlung von krebs im frühstadium |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20030133872A1 (de) |
| EP (1) | EP1438076B1 (de) |
| JP (1) | JP2005507001A (de) |
| AT (1) | ATE329623T1 (de) |
| DE (1) | DE60212424T2 (de) |
| WO (1) | WO2003035114A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005049096A2 (en) * | 2003-11-14 | 2005-06-02 | Dow Global Technologies Inc. | Protein and polymer conjugates as chelants with enhanced blood retention |
| EP1778699A4 (de) * | 2004-08-10 | 2009-02-25 | Dow Global Technologies Inc | Targeting von chelanten und chelaten |
| MX2018000239A (es) * | 2015-07-07 | 2018-05-23 | Five Eleven Pharma Inc | Bifosfonatos de hbed, sus conjugados radio metalicos y su uso como agentes teranosticos. |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3994996A (en) * | 1972-02-11 | 1976-11-30 | Fmc Corporation | Polymeric phosphazenes and process for preparation |
| US4662420A (en) * | 1981-10-05 | 1987-05-05 | Sanwa Shutter Corporation | Panel shutter mechanism |
| US4454106A (en) * | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
| US5362476A (en) * | 1984-10-18 | 1994-11-08 | Board Of Regents, The University Of Texas System | Alkyl phosphonate polyazamacrocyclic cheates for MRI |
| US4779930A (en) * | 1987-09-17 | 1988-10-25 | Rosen Steven B | Infant head support for use with infant retaining devices |
| US5739294A (en) * | 1991-12-10 | 1998-04-14 | The Dow Chemical Company | Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents |
| US5428139A (en) * | 1991-12-10 | 1995-06-27 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals |
| US5714604A (en) * | 1993-05-06 | 1998-02-03 | The Dow Chemical Company | Process for the preparation of azamacrocyclic or acyclic aminophosphonate ester derivatives |
| KR20000010533A (ko) * | 1996-04-19 | 2000-02-15 | 텍사스 테크 유니버시티 | 시각적 조직 특이성 조영제로서의 형광 킬레이트 |
| US6670456B2 (en) * | 2001-02-28 | 2003-12-30 | Dow Global Technologies Inc. | Actinium-225 complexes and conjugates for targeted radiotherapy |
| US7338651B2 (en) * | 2001-09-04 | 2008-03-04 | Texas Tech University System | Multi-use multimodal imaging chelates |
-
2002
- 2002-10-22 EP EP02789260A patent/EP1438076B1/de not_active Expired - Lifetime
- 2002-10-22 DE DE60212424T patent/DE60212424T2/de not_active Expired - Fee Related
- 2002-10-22 US US10/278,558 patent/US20030133872A1/en not_active Abandoned
- 2002-10-22 WO PCT/US2002/033918 patent/WO2003035114A1/en active IP Right Grant
- 2002-10-22 AT AT02789260T patent/ATE329623T1/de not_active IP Right Cessation
- 2002-10-22 JP JP2003537678A patent/JP2005507001A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1438076A1 (de) | 2004-07-21 |
| US20030133872A1 (en) | 2003-07-17 |
| EP1438076B1 (de) | 2006-06-14 |
| DE60212424T2 (de) | 2006-10-12 |
| ATE329623T1 (de) | 2006-07-15 |
| WO2003035114A1 (en) | 2003-05-01 |
| JP2005507001A (ja) | 2005-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |