DE60210600D1 - Mikrofluidfraktionssammler - Google Patents
MikrofluidfraktionssammlerInfo
- Publication number
- DE60210600D1 DE60210600D1 DE60210600T DE60210600T DE60210600D1 DE 60210600 D1 DE60210600 D1 DE 60210600D1 DE 60210600 T DE60210600 T DE 60210600T DE 60210600 T DE60210600 T DE 60210600T DE 60210600 D1 DE60210600 D1 DE 60210600D1
- Authority
- DE
- Germany
- Prior art keywords
- sample
- fluid flow
- flow control
- control mechanisms
- fraction collectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/80—Fraction collectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00801—Means to assemble
- B01J2219/0081—Plurality of modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00833—Plastic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
- B01J2219/00909—Separation using filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
- B01J2219/00916—Separation by chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
- B01J2219/00918—Separation by adsorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00952—Sensing operations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00952—Sensing operations
- B01J2219/00968—Type of sensors
- B01J2219/0097—Optical sensors
- B01J2219/00975—Ultraviolet light
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00952—Sensing operations
- B01J2219/00968—Type of sensors
- B01J2219/00981—Gas sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00986—Microprocessor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29689701P | 2001-06-07 | 2001-06-07 | |
US10/147,948 US20020186263A1 (en) | 2001-06-07 | 2002-05-16 | Microfluidic fraction collectors |
PCT/US2002/017721 WO2003008101A1 (en) | 2001-06-07 | 2002-06-04 | Microfluidic fraction collectors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60210600D1 true DE60210600D1 (de) | 2006-05-24 |
Family
ID=26845366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60210600T Expired - Lifetime DE60210600D1 (de) | 2001-06-07 | 2002-06-04 | Mikrofluidfraktionssammler |
Country Status (5)
Country | Link |
---|---|
US (1) | US20020186263A1 (de) |
EP (1) | EP1392436B1 (de) |
AT (1) | ATE322945T1 (de) |
DE (1) | DE60210600D1 (de) |
WO (1) | WO2003008101A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
US6919058B2 (en) | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
US6581441B1 (en) * | 2002-02-01 | 2003-06-24 | Perseptive Biosystems, Inc. | Capillary column chromatography process and system |
AU2003284055A1 (en) * | 2002-10-09 | 2004-05-04 | The Board Of Trustees Of The University Of Illinois | Microfluidic systems and components |
US20040129676A1 (en) * | 2003-01-07 | 2004-07-08 | Tan Roy H. | Apparatus for transfer of an array of liquids and methods for manufacturing same |
US20040227199A1 (en) * | 2003-05-15 | 2004-11-18 | Toshiba Kikai Kabushiki Kaisha | Minute flow passage and micro-chemical chip including the same |
US20080135484A1 (en) * | 2004-10-18 | 2008-06-12 | Hammer Michael R | Liquid Chromatography Apparatus |
WO2007114794A1 (en) * | 2006-03-31 | 2007-10-11 | Nam Trung Nguyen | Active control for droplet-based microfluidics |
US7744762B2 (en) * | 2006-08-24 | 2010-06-29 | Virginia Tech Intellectual Properties, Inc. | Microfluidic devices and methods facilitating high-throughput, on-chip detection and separation techniques |
WO2008070775A2 (en) * | 2006-12-06 | 2008-06-12 | The Curators Of The University Of Missouri | Liquid chromatography detector and flow controller therefor |
KR20090120457A (ko) * | 2006-12-06 | 2009-11-24 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | 액체 크로마토그래피 검출기 및 이를 위한 유동 제어기 |
US8032258B2 (en) * | 2007-12-04 | 2011-10-04 | Ludwig Lester F | Multi-channel chemical transport bus for microfluidic and other applications |
CA2684774A1 (en) | 2007-12-05 | 2009-06-18 | Alltech Associates, Inc. | Methods and apparatus for analyzing samples and collecting sample fractions |
US9133833B2 (en) | 2008-12-04 | 2015-09-15 | Alltech Associates, Inc. | Methods and apparatus for moving aliquot samples of fluid |
CN102316950A (zh) | 2008-12-10 | 2012-01-11 | 全技术联合公司 | 色谱系统和系统部件 |
US8314934B2 (en) | 2009-09-01 | 2012-11-20 | Alltech Associates, Inc. | Methods and apparatus for analyzing samples and collecting sample fractions |
DE102010053749B4 (de) * | 2010-12-08 | 2015-02-19 | Airbus Defence and Space GmbH | Vorrichtung zum Identifizieren biotischer Partikel |
DE102011054659A1 (de) * | 2011-10-20 | 2013-04-25 | AeroMegt GmbH | Verfahren und Vorrichtung zum Messen von Aerosolen in einem großen Volumenstrom |
GB201320146D0 (en) | 2013-11-14 | 2014-01-01 | Cambridge Entpr Ltd | Fluidic separation and detection |
CN107666963A (zh) * | 2015-04-08 | 2018-02-06 | 皇家飞利浦有限公司 | 用于多种检测形态的单个盒 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1252428B (de) * | 1965-12-03 | 1900-01-01 | ||
US3680576A (en) * | 1970-09-02 | 1972-08-01 | Bendix Corp | Bonded metal structure having intricate passages formed therein, and a method of making said structures |
US3756459A (en) * | 1971-01-12 | 1973-09-04 | Damon Corp | Method and apparatus for metering fluid utilizing pressure differentials |
DE2338458A1 (de) * | 1973-07-28 | 1975-02-06 | Karl Hehl | Mehrfachduese einer spritzgiessmaschine |
US4259291A (en) * | 1979-07-13 | 1981-03-31 | Technicon Instruments Corporation | Metering device |
US4676274A (en) * | 1985-02-28 | 1987-06-30 | Brown James F | Capillary flow control |
US4674323A (en) * | 1985-07-31 | 1987-06-23 | The Dow Chemical Company | Self-diagnostic gel permeation/size exclusion chromatograph |
EP0484278B1 (de) * | 1990-11-01 | 1995-04-12 | Ciba-Geigy Ag | Vorrichtung zur Aufbereitung oder Vorbereitung von flüssigen Proben für eine chemische Analyse |
US5230866A (en) * | 1991-03-01 | 1993-07-27 | Biotrack, Inc. | Capillary stop-flow junction having improved stability against accidental fluid flow |
WO1992017259A1 (en) * | 1991-03-28 | 1992-10-15 | Perseptive Biosystems, Inc. | On-line product identification in a chromatography effluent by subtraction |
KR100327521B1 (ko) * | 1993-03-19 | 2002-07-03 | 이.아이,듀우판드네모아앤드캄파니 | 일체형화학가공장치및그제조방법 |
DE69431994T2 (de) * | 1993-10-04 | 2003-10-30 | Res Int Inc | Mikro-bearbeitetes fluidbehandlungsvorrichtung mit filter und regelventiler |
DE4405005A1 (de) * | 1994-02-17 | 1995-08-24 | Rossendorf Forschzent | Mikro-Fluiddiode |
US6129973A (en) * | 1994-07-29 | 2000-10-10 | Battelle Memorial Institute | Microchannel laminated mass exchanger and method of making |
US5658413A (en) * | 1994-10-19 | 1997-08-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
US5834314A (en) * | 1994-11-07 | 1998-11-10 | Abbott Laboratories | Method and apparatus for metering a fluid |
EP0791238B1 (de) * | 1994-11-10 | 2004-09-22 | Orchid BioSciences, Inc. | Flüssigkeitsverteilungssystem |
US5856174A (en) * | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
DE29517100U1 (de) * | 1995-10-17 | 1997-02-13 | Zimmer, Johannes, Klagenfurt | Strömungsteilungs- und -umformungskörper |
US5958344A (en) * | 1995-11-09 | 1999-09-28 | Sarnoff Corporation | System for liquid distribution |
US6068751A (en) * | 1995-12-18 | 2000-05-30 | Neukermans; Armand P. | Microfluidic valve and integrated microfluidic system |
US5863502A (en) * | 1996-01-24 | 1999-01-26 | Sarnoff Corporation | Parallel reaction cassette and associated devices |
US6221654B1 (en) * | 1996-09-25 | 2001-04-24 | California Institute Of Technology | Method and apparatus for analysis and sorting of polynucleotides based on size |
US6123316A (en) * | 1996-11-27 | 2000-09-26 | Xerox Corporation | Conduit system for a valve array |
DE19704477A1 (de) * | 1997-02-06 | 1998-08-13 | Solvay Pharm Gmbh | Vorrichtung und Verfahren zur Parallel-Chromatographie |
US6154226A (en) * | 1997-05-13 | 2000-11-28 | Sarnoff Corporation | Parallel print array |
WO1999022228A1 (en) * | 1997-10-24 | 1999-05-06 | Northeastern University | A multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis |
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US6074725A (en) * | 1997-12-10 | 2000-06-13 | Caliper Technologies Corp. | Fabrication of microfluidic circuits by printing techniques |
US6167910B1 (en) * | 1998-01-20 | 2001-01-02 | Caliper Technologies Corp. | Multi-layer microfluidic devices |
US6117396A (en) * | 1998-02-18 | 2000-09-12 | Orchid Biocomputer, Inc. | Device for delivering defined volumes |
AU765096B2 (en) * | 1998-03-23 | 2003-09-11 | Amalgamated ResearchLLC | Fractal stack for scaling and distribution of fluids |
US6191418B1 (en) * | 1998-03-27 | 2001-02-20 | Synsorb Biotech, Inc. | Device for delivery of multiple liquid sample streams to a mass spectrometer |
AU763433B2 (en) * | 1998-05-22 | 2003-07-24 | California Institute Of Technology | Microfabricated cell sorter |
EP0966022B1 (de) * | 1998-06-18 | 2007-05-30 | Micromass UK Limited | Mehrfachprobeninlassmassenspektrometer |
US6494614B1 (en) * | 1998-07-27 | 2002-12-17 | Battelle Memorial Institute | Laminated microchannel devices, mixing units and method of making same |
DE19847952C2 (de) * | 1998-09-01 | 2000-10-05 | Inst Physikalische Hochtech Ev | Fluidstromschalter |
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WO2000031602A1 (de) * | 1998-11-20 | 2000-06-02 | Sepiatec Gmbh | Verfahren und vorrichtung zur regelung einzelner teilströme eines fördersystems für fluide medien |
JP2000214151A (ja) * | 1999-01-25 | 2000-08-04 | Shimadzu Corp | 液体クロマトグラフ分取装置 |
US6641783B1 (en) * | 1999-02-08 | 2003-11-04 | Charles Pidgeon | Chromatographic systems with pre-detector eluent switching |
ATE419911T1 (de) * | 1999-04-23 | 2009-01-15 | Advion Biosystems Inc | Parallel ausgeführte flüssigkeitschromatographievorrichtung mit hohem durchsatz |
US6263918B1 (en) * | 1999-04-29 | 2001-07-24 | The Regents Of The University Of California | Multiple feed powder splitter |
CN100402850C (zh) * | 1999-06-28 | 2008-07-16 | 加利福尼亚技术学院 | 微型制造的弹性体的阀和泵系统 |
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US6268219B1 (en) * | 1999-07-09 | 2001-07-31 | Orchid Biosciences, Inc. | Method and apparatus for distributing fluid in a microfluidic device |
US6537506B1 (en) * | 2000-02-03 | 2003-03-25 | Cellular Process Chemistry, Inc. | Miniaturized reaction apparatus |
JP2003532117A (ja) * | 2000-04-13 | 2003-10-28 | サーモ フィニガン リミテッド ライアビリティ カンパニー | 並列質量分析によるプロテオミクス解析 |
US6481453B1 (en) * | 2000-04-14 | 2002-11-19 | Nanostream, Inc. | Microfluidic branch metering systems and methods |
US7351376B1 (en) * | 2000-06-05 | 2008-04-01 | California Institute Of Technology | Integrated active flux microfluidic devices and methods |
US20020189947A1 (en) * | 2001-06-13 | 2002-12-19 | Eksigent Technologies Llp | Electroosmotic flow controller |
US6581441B1 (en) * | 2002-02-01 | 2003-06-24 | Perseptive Biosystems, Inc. | Capillary column chromatography process and system |
-
2002
- 2002-05-16 US US10/147,948 patent/US20020186263A1/en not_active Abandoned
- 2002-06-04 DE DE60210600T patent/DE60210600D1/de not_active Expired - Lifetime
- 2002-06-04 EP EP02763202A patent/EP1392436B1/de not_active Expired - Lifetime
- 2002-06-04 AT AT02763202T patent/ATE322945T1/de not_active IP Right Cessation
- 2002-06-04 WO PCT/US2002/017721 patent/WO2003008101A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1392436A1 (de) | 2004-03-03 |
WO2003008101A1 (en) | 2003-01-30 |
ATE322945T1 (de) | 2006-04-15 |
EP1392436B1 (de) | 2006-04-12 |
US20020186263A1 (en) | 2002-12-12 |
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