DE60208534D1 - Verwendung von antikörper gegen mag zur behandlung ischämischer schlaganfälle - Google Patents
Verwendung von antikörper gegen mag zur behandlung ischämischer schlaganfälleInfo
- Publication number
- DE60208534D1 DE60208534D1 DE60208534T DE60208534T DE60208534D1 DE 60208534 D1 DE60208534 D1 DE 60208534D1 DE 60208534 T DE60208534 T DE 60208534T DE 60208534 T DE60208534 T DE 60208534T DE 60208534 D1 DE60208534 D1 DE 60208534D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- antibody against
- ischemic attacks
- mag
- against mag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0103174.9A GB0103174D0 (en) | 2001-02-08 | 2001-02-08 | Novel method of treatment |
GB0103174 | 2001-02-08 | ||
PCT/GB2002/000551 WO2002062383A2 (en) | 2001-02-08 | 2002-02-08 | Antagonists of myelin-associated glycoprotein and their use in the treatment and/or prevention of neurological diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60208534D1 true DE60208534D1 (de) | 2006-03-30 |
DE60208534T2 DE60208534T2 (de) | 2006-11-30 |
Family
ID=9908386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60208534T Expired - Lifetime DE60208534T2 (de) | 2001-02-08 | 2002-02-08 | Verwendung von antikörper gegen mag zur behandlung ischämischer schlaganfälle |
Country Status (11)
Country | Link |
---|---|
US (2) | US20040170627A1 (de) |
EP (2) | EP1645285A3 (de) |
JP (2) | JP5005156B2 (de) |
AT (1) | ATE314861T1 (de) |
AU (1) | AU2002229928A1 (de) |
CY (1) | CY1105549T1 (de) |
DE (1) | DE60208534T2 (de) |
DK (1) | DK1357941T3 (de) |
ES (1) | ES2254655T3 (de) |
GB (1) | GB0103174D0 (de) |
WO (1) | WO2002062383A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
US20040151721A1 (en) | 2001-10-19 | 2004-08-05 | O'keefe Theresa | Humanized anti-CCR2 antibodies and methods of use therefor |
AR040778A1 (es) * | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
GB0306309D0 (en) * | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
CA2525784C (en) * | 2003-05-16 | 2019-04-09 | Acorda Therapeutics, Inc. | Proteoglycan degrading mutants for treatment of cns |
US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
JP2007521248A (ja) * | 2003-12-10 | 2007-08-02 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | ヒト化抗ccr2抗体および該抗体を使用する方法 |
US7485295B2 (en) | 2005-09-26 | 2009-02-03 | Acorda Therapeutics, Inc. | Compositions and methods of using chondroitinase ABCI mutants |
WO2009009406A1 (en) * | 2007-07-06 | 2009-01-15 | Smithkline Beecham Corporation | Antibody formulations |
US8974782B2 (en) | 2011-02-07 | 2015-03-10 | Glaxo Group Limited | Treatment of stroke comprising anti-MAG antibodies |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
US5250414A (en) * | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5527527A (en) * | 1989-09-07 | 1996-06-18 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical agent conjugates |
US5154924A (en) * | 1989-09-07 | 1992-10-13 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical agent conjugates |
US5182107A (en) * | 1989-09-07 | 1993-01-26 | Alkermes, Inc. | Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates |
GB9403250D0 (en) * | 1994-02-21 | 1994-04-13 | Univ Mcgill | Therapeutic use of myelin-associated glycoprotein (mag) |
US6576607B1 (en) * | 1995-04-19 | 2003-06-10 | Acorda Therapeutics | Methods using CNS neurite outgrowth modulators |
US5792743A (en) * | 1995-04-19 | 1998-08-11 | Acorda Therapeutics | Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule |
US5932542A (en) * | 1995-06-27 | 1999-08-03 | Research Foundation Of Cuny, Hunter College | Composition and methods using myelin-associated glycoprotein (MAG) and inhibitors thereof |
EP1047449B1 (de) * | 1997-10-28 | 2003-09-10 | The University Of British Columbia | Immunologische zusammensetzungen und verfahren zur transienten änderung des zentralnervensystem-myelins der saügetiere und förderung der nerven-regenerierung |
EP1030684A4 (de) * | 1997-11-14 | 2004-09-15 | Euro Celtique Sa | Modifizierte antikörper mit verstärkter fähigkeit eine anti-idiotypische antwort auszulösen |
AU3134799A (en) * | 1998-04-16 | 1999-11-08 | Peter Erich Braun | Nevron growth inhibitory molecules or derivatives thereof used to immunize mammals thereby promoting axon regeneration |
GB9908533D0 (en) * | 1999-04-14 | 1999-06-09 | Novartis Ag | Organic compounds |
GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
US20040002790A1 (en) * | 2002-06-28 | 2004-01-01 | Paul Senn | Sensitive devices and sensitive applications |
AR040778A1 (es) * | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
GB0306309D0 (en) * | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
-
2001
- 2001-02-08 GB GBGB0103174.9A patent/GB0103174D0/en not_active Ceased
-
2002
- 2002-02-08 DE DE60208534T patent/DE60208534T2/de not_active Expired - Lifetime
- 2002-02-08 ES ES02711034T patent/ES2254655T3/es not_active Expired - Lifetime
- 2002-02-08 AU AU2002229928A patent/AU2002229928A1/en not_active Abandoned
- 2002-02-08 DK DK02711034T patent/DK1357941T3/da active
- 2002-02-08 EP EP05077130A patent/EP1645285A3/de not_active Withdrawn
- 2002-02-08 JP JP2002562389A patent/JP5005156B2/ja not_active Expired - Fee Related
- 2002-02-08 US US10/467,253 patent/US20040170627A1/en not_active Abandoned
- 2002-02-08 WO PCT/GB2002/000551 patent/WO2002062383A2/en active IP Right Grant
- 2002-02-08 AT AT02711034T patent/ATE314861T1/de active
- 2002-02-08 EP EP02711034A patent/EP1357941B1/de not_active Expired - Lifetime
-
2006
- 2006-02-01 CY CY20061100125T patent/CY1105549T1/el unknown
-
2007
- 2007-05-09 US US11/746,355 patent/US20080014195A1/en not_active Abandoned
-
2008
- 2008-05-27 JP JP2008137916A patent/JP2008291031A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP1357941A2 (de) | 2003-11-05 |
US20080014195A1 (en) | 2008-01-17 |
EP1645285A3 (de) | 2010-04-14 |
EP1357941B1 (de) | 2006-01-04 |
AU2002229928A1 (en) | 2002-08-19 |
US20040170627A1 (en) | 2004-09-02 |
DK1357941T3 (da) | 2006-05-01 |
ES2254655T3 (es) | 2006-06-16 |
JP2004523538A (ja) | 2004-08-05 |
ATE314861T1 (de) | 2006-02-15 |
DE60208534T2 (de) | 2006-11-30 |
JP5005156B2 (ja) | 2012-08-22 |
JP2008291031A (ja) | 2008-12-04 |
CY1105549T1 (el) | 2010-07-28 |
GB0103174D0 (en) | 2001-03-28 |
WO2002062383A3 (en) | 2003-04-10 |
EP1645285A2 (de) | 2006-04-12 |
WO2002062383A2 (en) | 2002-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |