DE60207399D1 - Alkoxycarbonylaminobenzoesäure- oder alkoxycarbonylaminotetrazolylphenylderivate als ip-antagonisten - Google Patents
Alkoxycarbonylaminobenzoesäure- oder alkoxycarbonylaminotetrazolylphenylderivate als ip-antagonistenInfo
- Publication number
- DE60207399D1 DE60207399D1 DE60207399T DE60207399T DE60207399D1 DE 60207399 D1 DE60207399 D1 DE 60207399D1 DE 60207399 T DE60207399 T DE 60207399T DE 60207399 T DE60207399 T DE 60207399T DE 60207399 D1 DE60207399 D1 DE 60207399D1
- Authority
- DE
- Germany
- Prior art keywords
- alkoxycarbonylaminotetrozolylphenyl
- alkoxycarbonylaminobenoic
- antagonists
- derivatives
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002253 acid Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27287201P | 2001-03-02 | 2001-03-02 | |
US272872P | 2001-03-02 | ||
US31255901P | 2001-08-15 | 2001-08-15 | |
US312559P | 2001-08-15 | ||
PCT/EP2002/001943 WO2002070500A1 (en) | 2001-03-02 | 2002-02-25 | Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as ip antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60207399D1 true DE60207399D1 (de) | 2005-12-22 |
DE60207399T2 DE60207399T2 (de) | 2006-08-03 |
Family
ID=26955795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60207399T Expired - Fee Related DE60207399T2 (de) | 2001-03-02 | 2002-02-25 | Alkoxycarbonylaminobenzoesäure- oder alkoxycarbonylaminotetrazolylphenylderivate als ip-antagonisten |
Country Status (16)
Country | Link |
---|---|
US (1) | US6903086B2 (de) |
EP (1) | EP1379516B1 (de) |
JP (1) | JP4018985B2 (de) |
KR (1) | KR100559015B1 (de) |
CN (1) | CN1256334C (de) |
AR (1) | AR033430A1 (de) |
AT (1) | ATE309994T1 (de) |
AU (1) | AU2002253061B2 (de) |
BR (1) | BR0207795A (de) |
CA (1) | CA2438737A1 (de) |
DE (1) | DE60207399T2 (de) |
ES (1) | ES2252443T3 (de) |
MX (1) | MXPA03007865A (de) |
PA (1) | PA8540601A1 (de) |
PE (1) | PE20020905A1 (de) |
WO (1) | WO2002070500A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0218876D0 (en) * | 2002-08-13 | 2002-09-25 | Merck Sharp & Dohme | Therapeutic agents |
JP2006517576A (ja) * | 2003-02-14 | 2006-07-27 | メディカル リサーチ カウンシル | 病理的子宮症状の治療のためのipレセプターアンタゴニスト |
GB0503056D0 (en) * | 2005-02-14 | 2005-03-23 | Smithkline Beecham Corp | Chemical compounds |
US8076491B2 (en) * | 2007-08-21 | 2011-12-13 | Senomyx, Inc. | Compounds that inhibit (block) bitter taste in composition and use thereof |
KR101558193B1 (ko) * | 2007-08-21 | 2015-10-12 | 세노믹스, 인코포레이티드 | 인간 t2r 쓴맛 수용체 및 이의 용도 |
GB0907551D0 (en) * | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
US9321745B2 (en) | 2013-03-12 | 2016-04-26 | Allergan, Inc. | Inhibition of neovascularization by inhibition of prostanoid IP receptors |
US9295665B2 (en) | 2013-03-12 | 2016-03-29 | Allergan, Inc. | Inhibition of neovascularization by simultaneous inhibition of prostanoid IP and EP4 receptors |
CN106496036A (zh) * | 2016-09-29 | 2017-03-15 | 福建天富生物科技发展有限公司 | 一种抗凝血药物中间体5‑甲氧基‑2‑硝基苯甲酸的制备方法 |
US20200383967A1 (en) * | 2017-08-07 | 2020-12-10 | Hiroshima University | Novel Anthranilic Acid-Based Compound, and Pin1 Inhibitor, Therapeutic Agent for Inflammatory Diseases and Therapeutic Agent for Cancer That Use the Same |
EP3746134A1 (de) | 2018-02-02 | 2020-12-09 | Maverix Oncology, Inc. | Kleinmolekülige wirkstoffkonjugate von gemcitabinmonophosphat |
CN108774183A (zh) * | 2018-08-03 | 2018-11-09 | 成都苑东生物制药股份有限公司 | 一种乙二醇类化合物的制备方法 |
EP4119138A1 (de) * | 2021-07-12 | 2023-01-18 | Universität Hamburg | Dhodh-inhibitoren und ihre verwendung als antivirale mittel |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6174905B1 (en) | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
US5998424A (en) | 1997-06-19 | 1999-12-07 | Dupont Pharmaceuticals Company | Inhibitors of factor Xa with a neutral P1 specificity group |
US6184242B1 (en) | 1997-09-04 | 2001-02-06 | Syntex Usa (Llc) | 2-(substituted-phenyl)amino-imidazoline derivatives |
US6320078B1 (en) | 1998-07-24 | 2001-11-20 | Mitsui Chemicals, Inc. | Method of producing benzamide derivatives |
KR20010072080A (ko) | 1998-07-31 | 2001-07-31 | 쓰끼하시 다미까따 | 페닐아졸 화합물, 그의 제조 방법 및 고지혈증용 약제 |
JP3938689B2 (ja) * | 2000-03-16 | 2007-06-27 | エフ.ホフマン−ラ ロシュ アーゲー | Ipアンタゴニストとしてのカルボン酸誘導体 |
-
2002
- 2002-02-25 CA CA002438737A patent/CA2438737A1/en not_active Abandoned
- 2002-02-25 EP EP02722127A patent/EP1379516B1/de not_active Expired - Lifetime
- 2002-02-25 JP JP2002569820A patent/JP4018985B2/ja not_active Expired - Fee Related
- 2002-02-25 BR BR0207795-7A patent/BR0207795A/pt not_active IP Right Cessation
- 2002-02-25 MX MXPA03007865A patent/MXPA03007865A/es active IP Right Grant
- 2002-02-25 CN CNB028058704A patent/CN1256334C/zh not_active Expired - Fee Related
- 2002-02-25 AT AT02722127T patent/ATE309994T1/de not_active IP Right Cessation
- 2002-02-25 AU AU2002253061A patent/AU2002253061B2/en not_active Ceased
- 2002-02-25 KR KR1020037011543A patent/KR100559015B1/ko not_active IP Right Cessation
- 2002-02-25 ES ES02722127T patent/ES2252443T3/es not_active Expired - Lifetime
- 2002-02-25 DE DE60207399T patent/DE60207399T2/de not_active Expired - Fee Related
- 2002-02-25 WO PCT/EP2002/001943 patent/WO2002070500A1/en active IP Right Grant
- 2002-02-26 PA PA20028540601A patent/PA8540601A1/es unknown
- 2002-02-28 AR ARP020100716A patent/AR033430A1/es unknown
- 2002-02-28 PE PE2002000168A patent/PE20020905A1/es not_active Application Discontinuation
- 2002-03-01 US US10/087,034 patent/US6903086B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020165235A1 (en) | 2002-11-07 |
AU2002253061B2 (en) | 2005-04-07 |
AR033430A1 (es) | 2003-12-17 |
US6903086B2 (en) | 2005-06-07 |
CN1527824A (zh) | 2004-09-08 |
CA2438737A1 (en) | 2002-09-12 |
MXPA03007865A (es) | 2003-12-04 |
JP4018985B2 (ja) | 2007-12-05 |
KR100559015B1 (ko) | 2006-03-10 |
ES2252443T3 (es) | 2006-05-16 |
EP1379516A1 (de) | 2004-01-14 |
JP2004529899A (ja) | 2004-09-30 |
BR0207795A (pt) | 2004-03-23 |
CN1256334C (zh) | 2006-05-17 |
PE20020905A1 (es) | 2002-10-19 |
DE60207399T2 (de) | 2006-08-03 |
KR20040023591A (ko) | 2004-03-18 |
PA8540601A1 (es) | 2002-09-30 |
EP1379516B1 (de) | 2005-11-16 |
WO2002070500A1 (en) | 2002-09-12 |
ATE309994T1 (de) | 2005-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |