DE60205487D1 - Verfahren zur verbesserung des durchflusses einer aerosolformulierung in einem dosierventil für einen dosierinhalator - Google Patents

Verfahren zur verbesserung des durchflusses einer aerosolformulierung in einem dosierventil für einen dosierinhalator

Info

Publication number
DE60205487D1
DE60205487D1 DE60205487T DE60205487T DE60205487D1 DE 60205487 D1 DE60205487 D1 DE 60205487D1 DE 60205487 T DE60205487 T DE 60205487T DE 60205487 T DE60205487 T DE 60205487T DE 60205487 D1 DE60205487 D1 DE 60205487D1
Authority
DE
Germany
Prior art keywords
dosing
improving
flow
aerosol formulation
inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60205487T
Other languages
English (en)
Other versions
DE60205487T2 (de
Inventor
M Arsenault
H Castro
Thomas Herdtle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of DE60205487D1 publication Critical patent/DE60205487D1/de
Application granted granted Critical
Publication of DE60205487T2 publication Critical patent/DE60205487T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
DE60205487T 2001-06-22 2002-05-14 Verfahren zur verbesserung des durchflusses einer aerosolformulierung in einem dosierventil für einen dosierinhalator Expired - Fee Related DE60205487T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30028701P 2001-06-22 2001-06-22
US300287P 2001-06-22
PCT/US2002/015506 WO2003000570A1 (en) 2001-06-22 2002-05-14 Metering valve for a metered dose inhaler

Publications (2)

Publication Number Publication Date
DE60205487D1 true DE60205487D1 (de) 2005-09-15
DE60205487T2 DE60205487T2 (de) 2006-06-01

Family

ID=23158471

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60205487T Expired - Fee Related DE60205487T2 (de) 2001-06-22 2002-05-14 Verfahren zur verbesserung des durchflusses einer aerosolformulierung in einem dosierventil für einen dosierinhalator

Country Status (5)

Country Link
US (1) US20030010794A1 (de)
EP (1) EP1399374B1 (de)
AT (1) ATE301594T1 (de)
DE (1) DE60205487T2 (de)
WO (1) WO2003000570A1 (de)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
SI1494732T1 (sl) 2002-03-20 2008-08-31 Mannking Corp Inhalacijski aparat
ATE532547T1 (de) 2002-09-06 2011-11-15 3M Innovative Properties Co Dosierventil für einen dosierinhalator mit konsistenter abgabe
GB0315791D0 (en) 2003-07-07 2003-08-13 3M Innovative Properties Co Two component molded valve stems
JP5078014B2 (ja) 2004-08-20 2012-11-21 マンカインド コーポレイション ジケトピペラジン合成の触媒反応
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
WO2006065588A2 (en) * 2004-12-15 2006-06-22 3M Innovative Properties Company Elastomer seals for use in medicinal aerosol devices
EP1928423B1 (de) 2005-09-14 2015-12-09 Mannkind Corporation Verfahren zur arzneimittelformulierung basierend auf der affinitätssteigerung von aktiven wirkstoffen für kristalline mikropartikel-flächen
EP1986679B1 (de) 2006-02-22 2017-10-25 MannKind Corporation Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff
US20090050143A1 (en) * 2006-03-24 2009-02-26 Boardman Larry D Medicinal formulation container with a treated metal surface
WO2007112271A2 (en) * 2006-03-24 2007-10-04 3M Innovative Properties Company Method for assessing the suitability of metered dose inhaler actuators
US20090298131A1 (en) * 2008-02-19 2009-12-03 Intelligent Biosystems, Inc. Non-Emulsion Methods And Masked Biomolecules
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101558026B1 (ko) 2008-06-13 2015-10-06 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2440184B1 (de) 2009-06-12 2023-04-05 MannKind Corporation Diketopiperazin-mikropartikel mit definierten spefiischen oberflächenbereichen
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CA2801936C (en) 2010-06-21 2021-06-01 Mannkind Corporation Dry powder drug delivery system and methods
KR101940832B1 (ko) 2011-04-01 2019-01-21 맨카인드 코포레이션 의약 카트리지용 블리스터 패키지
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2776053A1 (de) 2011-10-24 2014-09-17 MannKind Corporation Verfahren und zusammensetzungen zur schmerzbehandlung
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
US9554982B2 (en) 2012-09-14 2017-01-31 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US9579265B2 (en) 2014-03-13 2017-02-28 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
US9662285B2 (en) 2014-03-13 2017-05-30 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
GB201702406D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2004526B (en) * 1977-09-22 1982-07-28 Glaxo Group Ltd Aerosol valve
GB8503553D0 (en) * 1985-02-12 1985-03-13 Bespak Plc Valves for pressurised dispensing containers
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
FR2615124B1 (fr) * 1987-05-12 1989-11-24 Valois Valve aerosol doseuse a propulseur, utilisable en position inversee
US5400920A (en) * 1993-07-29 1995-03-28 Minnesota Mining And Manufacturing Company One-time fill aerosol valve
GB2311982B (en) * 1996-04-09 2000-03-08 Bespak Plc Improvements in or relating to valves for dispensers
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
GB2360272B (en) * 2000-03-07 2002-02-13 Bespak Plc Improvements in or relating to valves for dispensers
ATE273206T1 (de) * 2001-03-26 2004-08-15 3M Innovative Properties Co Dossierventil für einen dosierinhalator mit verbessertem fluss

Also Published As

Publication number Publication date
WO2003000570A1 (en) 2003-01-03
WO2003000570A8 (en) 2004-04-29
DE60205487T2 (de) 2006-06-01
US20030010794A1 (en) 2003-01-16
EP1399374A1 (de) 2004-03-24
ATE301594T1 (de) 2005-08-15
EP1399374B1 (de) 2005-08-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee