DE60204701T2 - Tricyclische imidazopyridine - Google Patents

Tricyclische imidazopyridine Download PDF

Info

Publication number
DE60204701T2
DE60204701T2 DE60204701T DE60204701T DE60204701T2 DE 60204701 T2 DE60204701 T2 DE 60204701T2 DE 60204701 T DE60204701 T DE 60204701T DE 60204701 T DE60204701 T DE 60204701T DE 60204701 T2 DE60204701 T2 DE 60204701T2
Authority
DE
Germany
Prior art keywords
alkyl
alkoxy
hydrogen
hydroxy
alkoxycarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60204701T
Other languages
German (de)
English (en)
Other versions
DE60204701D1 (de
Inventor
Wilm Buhr
Jörg Senn-Bilfinger
Jan Peter ZIMMERMANN
Wolfgang-Alexander Simon
Stefan Postius
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of DE60204701D1 publication Critical patent/DE60204701D1/de
Application granted granted Critical
Publication of DE60204701T2 publication Critical patent/DE60204701T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60204701T 2001-08-10 2002-07-31 Tricyclische imidazopyridine Expired - Fee Related DE60204701T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01119321 2001-08-10
EP01119321 2001-08-10
PCT/EP2002/008505 WO2003014123A1 (en) 2001-08-10 2002-07-31 Tricyclic imidazopyridines

Publications (2)

Publication Number Publication Date
DE60204701D1 DE60204701D1 (de) 2005-07-21
DE60204701T2 true DE60204701T2 (de) 2006-08-03

Family

ID=8178292

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60204701T Expired - Fee Related DE60204701T2 (de) 2001-08-10 2002-07-31 Tricyclische imidazopyridine

Country Status (24)

Country Link
US (1) US7223771B2 (enExample)
EP (1) EP1419163B9 (enExample)
JP (1) JP2005504761A (enExample)
KR (1) KR20040023739A (enExample)
CN (1) CN1329395C (enExample)
AT (1) ATE297931T1 (enExample)
BR (1) BR0211826A (enExample)
CA (1) CA2452803A1 (enExample)
DE (1) DE60204701T2 (enExample)
DK (1) DK1419163T5 (enExample)
EA (1) EA007683B1 (enExample)
ES (1) ES2243788T3 (enExample)
HR (1) HRP20040229A2 (enExample)
HU (1) HUP0500330A3 (enExample)
IL (1) IL159554A0 (enExample)
MX (1) MXPA04001277A (enExample)
NO (1) NO20040604L (enExample)
NZ (1) NZ531520A (enExample)
PL (1) PL368195A1 (enExample)
PT (1) PT1419163E (enExample)
SI (1) SI1419163T1 (enExample)
TW (1) TWD111798S1 (enExample)
WO (1) WO2003014123A1 (enExample)
ZA (1) ZA200400918B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004226180A1 (en) 2003-04-04 2004-10-14 Altana Pharma Ag Cyclic benzimidazoles
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
AU2004243444A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
AR046941A1 (es) * 2003-12-19 2006-01-04 Altana Pharma Ag Imidazopiridinas triciclicas y su uso como inhibidores de secrecion de acido gastrico
WO2005058894A1 (en) * 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR047605A1 (es) * 2004-02-17 2006-01-25 Altana Pharma Ag Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos.
EP1735318A2 (en) * 2004-03-17 2006-12-27 Altana Pharma AG 7h-8,9-dihydro-pyrano(2,3-c)imidazo(1,2a)pyridine derivatives and their use as gastric acid secretion inhibitors
EP1805173A2 (en) * 2004-03-22 2007-07-11 Altana Pharma AG 7, 8, 9, 10- tetrahydro-imidazo [2,1-a] isoquinoline derivatives and their use as gastric acid secretion inhibitors
AR048869A1 (es) * 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
ATE374774T1 (de) * 2004-06-09 2007-10-15 Nycomed Gmbh Substituierte tricyclische benzimidazole
AR051041A1 (es) * 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
AR054772A1 (es) * 2005-06-16 2007-07-18 Altana Pharma Ag Espiro- imidazopiridinas como inhibidores de la secrecion de acido gastrico
WO2007113226A1 (en) * 2006-03-31 2007-10-11 Novartis Ag Organic compounds
WO2008071766A2 (en) * 2006-12-14 2008-06-19 Nycomed Gmbh Spiro-indene substituted imidazonaphythyridine and pyranoimidazopyridine derivatives as inhibitors of gastric acid secretion
KR200452179Y1 (ko) * 2009-05-20 2011-02-10 주식회사 신성일렉스 항공 장애물 표시 장치
CN102470126A (zh) 2009-07-09 2012-05-23 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂
GB201321730D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
KR20250136992A (ko) * 2024-03-07 2025-09-17 대원제약주식회사 삼환식 유도체 및 이를 포함하는 약학적 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
ID22718A (id) * 1997-03-24 1999-12-09 Byk Gulden Lomberg Chem Fab Senyawa-senyawa tetrahidropirido
WO1998042707A1 (en) 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
IL132608A0 (en) * 1997-05-28 2001-03-19 Byk Gulden Lomberg Chem Fab Fused dihydropyran compounds medicaments containing the same and the use thereof
CN1221553C (zh) * 2000-03-29 2005-10-05 奥坦纳医药公司 三环咪唑并吡啶类化合物及药物组合物

Also Published As

Publication number Publication date
WO2003014123A1 (en) 2003-02-20
ES2243788T3 (es) 2005-12-01
KR20040023739A (ko) 2004-03-18
SI1419163T1 (sl) 2005-12-31
HK1066213A1 (en) 2005-03-18
HUP0500330A3 (en) 2009-12-28
CA2452803A1 (en) 2003-02-20
ZA200400918B (en) 2005-04-20
NO20040604L (no) 2004-02-10
MXPA04001277A (es) 2004-05-27
HRP20040229A2 (en) 2005-02-28
PT1419163E (pt) 2005-10-31
NZ531520A (en) 2005-10-28
CN1541219A (zh) 2004-10-27
DK1419163T5 (da) 2005-12-19
TWD111798S1 (zh) 2006-07-11
EP1419163B9 (en) 2005-11-09
DE60204701D1 (de) 2005-07-21
EP1419163B1 (en) 2005-06-15
BR0211826A (pt) 2005-06-28
EP1419163A1 (en) 2004-05-19
EA200400254A1 (ru) 2004-08-26
US7223771B2 (en) 2007-05-29
EA007683B1 (ru) 2006-12-29
CN1329395C (zh) 2007-08-01
PL368195A1 (en) 2005-03-21
JP2005504761A (ja) 2005-02-17
HUP0500330A2 (hu) 2005-07-28
US20050049272A1 (en) 2005-03-03
DK1419163T3 (da) 2005-10-17
IL159554A0 (en) 2004-06-01
ATE297931T1 (de) 2005-07-15

Similar Documents

Publication Publication Date Title
DE60204701T2 (de) Tricyclische imidazopyridine
US7307084B2 (en) Cyclic benzimidazoles
US20060148796A1 (en) 6-Substituted imidazopyrazines
US20080113962A1 (en) Condensed Tricyclic Benzimidazoles For the Treatment of Gastrointestinal Disorders
US20080033006A1 (en) 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
WO2006100255A1 (en) Thioamide-substituted tricyclic benzimidazoles useful for the treatment of gastrointestinal diseases
US20070167427A1 (en) 1,2,4-Triazolo[4,3-a]pyridines useful in the treatment of gastrointestinal disorders
US20070203114A1 (en) 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines
EP1718648B1 (en) Tricyclic imidazopyridines and intermediates for the synthesis thereof
US20070287726A1 (en) 5-Substituted 1H-Pyrrolo [3,2-B] Pyridines
AU2002333289A1 (en) Tricyclic imidazopyridines
HK1066213B (en) Tricyclic imidazopyridines

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE

8339 Ceased/non-payment of the annual fee