DE60204701T2 - Tricyclische imidazopyridine - Google Patents

Tricyclische imidazopyridine Download PDF

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Publication number
DE60204701T2
DE60204701T2 DE60204701T DE60204701T DE60204701T2 DE 60204701 T2 DE60204701 T2 DE 60204701T2 DE 60204701 T DE60204701 T DE 60204701T DE 60204701 T DE60204701 T DE 60204701T DE 60204701 T2 DE60204701 T2 DE 60204701T2
Authority
DE
Germany
Prior art keywords
alkyl
alkoxy
hydrogen
hydroxy
alkoxycarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60204701T
Other languages
German (de)
English (en)
Other versions
DE60204701D1 (de
Inventor
Wilm Buhr
Jörg Senn-Bilfinger
Jan Peter ZIMMERMANN
Wolfgang-Alexander Simon
Stefan Postius
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of DE60204701D1 publication Critical patent/DE60204701D1/de
Application granted granted Critical
Publication of DE60204701T2 publication Critical patent/DE60204701T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60204701T 2001-08-10 2002-07-31 Tricyclische imidazopyridine Expired - Fee Related DE60204701T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01119321 2001-08-10
EP01119321 2001-08-10
PCT/EP2002/008505 WO2003014123A1 (en) 2001-08-10 2002-07-31 Tricyclic imidazopyridines

Publications (2)

Publication Number Publication Date
DE60204701D1 DE60204701D1 (de) 2005-07-21
DE60204701T2 true DE60204701T2 (de) 2006-08-03

Family

ID=8178292

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60204701T Expired - Fee Related DE60204701T2 (de) 2001-08-10 2002-07-31 Tricyclische imidazopyridine

Country Status (24)

Country Link
US (1) US7223771B2 (enExample)
EP (1) EP1419163B9 (enExample)
JP (1) JP2005504761A (enExample)
KR (1) KR20040023739A (enExample)
CN (1) CN1329395C (enExample)
AT (1) ATE297931T1 (enExample)
BR (1) BR0211826A (enExample)
CA (1) CA2452803A1 (enExample)
DE (1) DE60204701T2 (enExample)
DK (1) DK1419163T5 (enExample)
EA (1) EA007683B1 (enExample)
ES (1) ES2243788T3 (enExample)
HR (1) HRP20040229A2 (enExample)
HU (1) HUP0500330A3 (enExample)
IL (1) IL159554A0 (enExample)
MX (1) MXPA04001277A (enExample)
NO (1) NO20040604L (enExample)
NZ (1) NZ531520A (enExample)
PL (1) PL368195A1 (enExample)
PT (1) PT1419163E (enExample)
SI (1) SI1419163T1 (enExample)
TW (1) TWD111798S1 (enExample)
WO (1) WO2003014123A1 (enExample)
ZA (1) ZA200400918B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087701A1 (en) * 2003-04-04 2004-10-14 Altana Pharma Ag Cyclic benzimidazoles
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
CA2526566A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
WO2005058894A1 (en) * 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR046941A1 (es) * 2003-12-19 2006-01-04 Altana Pharma Ag Imidazopiridinas triciclicas y su uso como inhibidores de secrecion de acido gastrico
AR047605A1 (es) * 2004-02-17 2006-01-25 Altana Pharma Ag Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos.
KR20070009614A (ko) * 2004-03-17 2007-01-18 알타나 파마 아게 7ｈ-8,9-디히드로-피라노(2,3-ｃ)이미다조(1,2-ａ)피리딘유도체 및 이의 위산 분비 억제제로서의 용도
US20070203114A1 (en) * 2004-03-22 2007-08-30 Andreas Palmer 7,8,9,10-Tetrahydro-Imidazo [2,1-A] Isochinolines
AR048869A1 (es) * 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
JP2008501766A (ja) * 2004-06-09 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換された三環式のベンゾイミダゾール
AR051041A1 (es) * 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
AR054772A1 (es) * 2005-06-16 2007-07-18 Altana Pharma Ag Espiro- imidazopiridinas como inhibidores de la secrecion de acido gastrico
JP2009531390A (ja) * 2006-03-31 2009-09-03 ノバルティス アクチエンゲゼルシャフト 有機化合物
WO2008071766A2 (en) * 2006-12-14 2008-06-19 Nycomed Gmbh Spiro-indene substituted imidazonaphythyridine and pyranoimidazopyridine derivatives as inhibitors of gastric acid secretion
KR200452179Y1 (ko) * 2009-05-20 2011-02-10 주식회사 신성일렉스 항공 장애물 표시 장치
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
GB201321730D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
KR20250136992A (ko) * 2024-03-07 2025-09-17 대원제약주식회사 삼환식 유도체 및 이를 포함하는 약학적 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
SE9401197D0 (sv) 1994-04-11 1994-04-11 Astra Ab Active compounds
BR9807883A (pt) * 1997-03-24 2000-02-22 Byk Gulden Lomberg Chem Fab Compostos de tetraidropirido
CA2289542A1 (en) 1997-05-28 1998-12-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Fused dihydropyrans
HUP0001555A3 (en) 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
WO2001072757A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Tricyclic imidazopyridines

Also Published As

Publication number Publication date
HRP20040229A2 (en) 2005-02-28
MXPA04001277A (es) 2004-05-27
ES2243788T3 (es) 2005-12-01
EA200400254A1 (ru) 2004-08-26
WO2003014123A1 (en) 2003-02-20
EP1419163A1 (en) 2004-05-19
ATE297931T1 (de) 2005-07-15
HK1066213A1 (en) 2005-03-18
BR0211826A (pt) 2005-06-28
ZA200400918B (en) 2005-04-20
DK1419163T3 (da) 2005-10-17
PT1419163E (pt) 2005-10-31
NO20040604L (no) 2004-02-10
EA007683B1 (ru) 2006-12-29
HUP0500330A3 (en) 2009-12-28
US7223771B2 (en) 2007-05-29
DE60204701D1 (de) 2005-07-21
NZ531520A (en) 2005-10-28
HUP0500330A2 (hu) 2005-07-28
CN1329395C (zh) 2007-08-01
SI1419163T1 (sl) 2005-12-31
CN1541219A (zh) 2004-10-27
IL159554A0 (en) 2004-06-01
DK1419163T5 (da) 2005-12-19
EP1419163B1 (en) 2005-06-15
JP2005504761A (ja) 2005-02-17
US20050049272A1 (en) 2005-03-03
CA2452803A1 (en) 2003-02-20
KR20040023739A (ko) 2004-03-18
PL368195A1 (en) 2005-03-21
TWD111798S1 (zh) 2006-07-11
EP1419163B9 (en) 2005-11-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE

8339 Ceased/non-payment of the annual fee