DE602008006206D1 - Sterilisationsverfahren für Chromatographisches Trennungs-Mittel - Google Patents

Sterilisationsverfahren für Chromatographisches Trennungs-Mittel

Info

Publication number
DE602008006206D1
DE602008006206D1 DE602008006206T DE602008006206T DE602008006206D1 DE 602008006206 D1 DE602008006206 D1 DE 602008006206D1 DE 602008006206 T DE602008006206 T DE 602008006206T DE 602008006206 T DE602008006206 T DE 602008006206T DE 602008006206 D1 DE602008006206 D1 DE 602008006206D1
Authority
DE
Germany
Prior art keywords
chromatographic separation
separation agent
sterilization procedure
sterilization
separation medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602008006206T
Other languages
English (en)
Inventor
Ingrid Drevin
Hamid Houshmand
Ola Lind
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Sweden AB
Original Assignee
GE Healthcare Bio Sciences AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences AB filed Critical GE Healthcare Bio Sciences AB
Publication of DE602008006206D1 publication Critical patent/DE602008006206D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A61L2/06—Hot gas
    • A61L2/07—Steam
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/34—Regenerating or reactivating
    • B01J20/345—Regenerating or reactivating using a particular desorbing compound or mixture
    • B01J20/3458—Regenerating or reactivating using a particular desorbing compound or mixture in the gas phase
    • B01J20/3466—Regenerating or reactivating using a particular desorbing compound or mixture in the gas phase with steam
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N30/54—Temperature

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DE602008006206T 2007-08-30 2008-08-27 Sterilisationsverfahren für Chromatographisches Trennungs-Mittel Active DE602008006206D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0716900A GB2452301A (en) 2007-08-30 2007-08-30 Sterilization Method
PCT/US2008/074383 WO2009032662A1 (en) 2007-08-30 2008-08-27 Sterilization method

Publications (1)

Publication Number Publication Date
DE602008006206D1 true DE602008006206D1 (de) 2011-05-26

Family

ID=38617021

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602008006206T Active DE602008006206D1 (de) 2007-08-30 2008-08-27 Sterilisationsverfahren für Chromatographisches Trennungs-Mittel

Country Status (8)

Country Link
US (1) US9101677B2 (de)
EP (1) EP2182990B1 (de)
JP (1) JP5985794B2 (de)
AT (1) ATE505209T1 (de)
DE (1) DE602008006206D1 (de)
ES (1) ES2362699T3 (de)
GB (1) GB2452301A (de)
WO (1) WO2009032662A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3015542A1 (de) 2015-05-07 2016-05-04 Bayer Technology Services GmbH Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes
EP3037513A1 (de) 2015-05-13 2016-06-29 Bayer Technology Services GmbH Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3706631A (en) * 1970-10-08 1972-12-19 John D Falk Sterilization of protein-containing fluids
US4028242A (en) * 1975-02-06 1977-06-07 Kokurin Vyacheslav Alexandrovi Method of thermal disinfection of sewage and plant realizing same
HU203252B (en) * 1986-01-16 1991-06-28 Nitrokemia Ipartelepek Process for producing ion-exchange resins with grain size mainly less than ten microns for analytical and preparative purposes
US4923068A (en) * 1989-02-07 1990-05-08 Cdp Product Development Corporation Automatic filter system
JPH0741167B2 (ja) * 1989-06-30 1995-05-10 株式会社クラレ 生理活性物質固定化吸着剤の製造方法および製造用キット
US5268144A (en) * 1989-11-04 1993-12-07 Fresenius Ag Method for sterilizing a medical unit
JP3161604B2 (ja) 1994-05-13 2001-04-25 プラズマセレクト ゲーエムベーハー テテロウ 血液中の物質を結合してそれを除去するためのタンパク質を結合させた、無菌かつ発熱物質を含有しないカラム
US5423982A (en) * 1994-05-31 1995-06-13 Biosepra Inc. Liquid chromatography column adapted for in situ chemical sterilization
GB9823071D0 (en) * 1998-10-21 1998-12-16 Affibody Technology Ab A method
SE0200943D0 (sv) * 2002-03-25 2002-03-25 Amersham Biosciences Ab Mutant protein
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
RU2367517C2 (ru) * 2004-09-22 2009-09-20 Джи-И Хелткер Байо-Сайенсиз АБ Способ получения хроматографической матрицы
CA2599650A1 (en) * 2005-03-07 2006-09-14 Ge Healthcare Bio-Sciences Ab Method of sterilization

Also Published As

Publication number Publication date
WO2009032662A1 (en) 2009-03-12
GB0716900D0 (en) 2007-10-10
EP2182990B1 (de) 2011-04-13
EP2182990A1 (de) 2010-05-12
GB2452301A (en) 2009-03-04
JP2010538271A (ja) 2010-12-09
ATE505209T1 (de) 2011-04-15
ES2362699T3 (es) 2011-07-12
US20110178271A1 (en) 2011-07-21
JP5985794B2 (ja) 2016-09-06
US9101677B2 (en) 2015-08-11

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