DE602007011973D1 - Stabile parenterale formulierung mit einem rsv-hemmer einer benzodiazepin-struktur - Google Patents

Stabile parenterale formulierung mit einem rsv-hemmer einer benzodiazepin-struktur

Info

Publication number
DE602007011973D1
DE602007011973D1 DE602007011973T DE602007011973T DE602007011973D1 DE 602007011973 D1 DE602007011973 D1 DE 602007011973D1 DE 602007011973 T DE602007011973 T DE 602007011973T DE 602007011973 T DE602007011973 T DE 602007011973T DE 602007011973 D1 DE602007011973 D1 DE 602007011973D1
Authority
DE
Germany
Prior art keywords
rsv
hemmer
parenteral formulation
benzodiazepine structure
stable parenteral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007011973T
Other languages
English (en)
Inventor
Thitiwan Buranachokpaisan
Wenlei Jiang
Wei-Qin Tong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE602007011973D1 publication Critical patent/DE602007011973D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602007011973T 2006-11-21 2007-11-20 Stabile parenterale formulierung mit einem rsv-hemmer einer benzodiazepin-struktur Active DE602007011973D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86664606P 2006-11-21 2006-11-21
PCT/US2007/024246 WO2008063634A1 (en) 2006-11-21 2007-11-20 Stable parenteral formulation containing a rsv inhibitor of a benzodiazepine structure

Publications (1)

Publication Number Publication Date
DE602007011973D1 true DE602007011973D1 (de) 2011-02-24

Family

ID=39156434

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007011973T Active DE602007011973D1 (de) 2006-11-21 2007-11-20 Stabile parenterale formulierung mit einem rsv-hemmer einer benzodiazepin-struktur

Country Status (16)

Country Link
US (1) US20100056500A1 (de)
EP (1) EP2094308B1 (de)
JP (1) JP2010510311A (de)
KR (1) KR20090087079A (de)
CN (1) CN101553258A (de)
AT (1) ATE494896T1 (de)
AU (1) AU2007321977A1 (de)
BR (1) BRPI0719096A2 (de)
CA (1) CA2669705A1 (de)
DE (1) DE602007011973D1 (de)
ES (1) ES2359856T3 (de)
MX (1) MX2009005368A (de)
PL (1) PL2094308T3 (de)
PT (1) PT2094308E (de)
RU (1) RU2009123536A (de)
WO (1) WO2008063634A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2121025T3 (en) * 2007-01-19 2017-01-30 Hananja Ehf Methods and compositions for delivering a therapeutic agent
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
AU2013203271B2 (en) * 2007-01-19 2016-05-12 Hananja Ehf Methods and compositions for the delivery of a therapeutic agent
WO2008152543A1 (en) * 2007-06-11 2008-12-18 The Procter & Gamble Company Benefit agent containing delivery particle
EP2238973A1 (de) * 2009-04-07 2010-10-13 Cephalon France Lyophilisierte Präparate von Proteasominhibitoren
WO2011151667A1 (en) 2010-06-02 2011-12-08 Adbula Kurkayev Antiviral compositions
BR112013002646B1 (pt) 2010-08-05 2022-01-04 Siga Technologies, Inc Formulações farmacêuticas líquidas e métodos e processo de preparo das mesmas e unidade de dosagem das referidas formulações líquidas
GB201613942D0 (en) * 2016-08-15 2016-09-28 Univ Of Durham The An antimicrobial compound
CN117355311A (zh) 2022-05-05 2024-01-05 阿卜杜拉·库尔卡耶夫 用于恢复生物体生理过程和细胞的药物组合物
WO2024086605A1 (en) * 2022-10-18 2024-04-25 Takeda Vaccines, Inc. Dengue vaccine formulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
AU759280C (en) * 1998-02-23 2004-01-22 Cyclops, Ehf High-energy cyclodextrin complexes
NZ511995A (en) * 1999-01-21 2003-11-28 Bristol Myers Squibb Co A ras-farnesyltransferase inhibitor complex that is stable and water soluble and useful as an anti-tumour agent
MXPA05002871A (es) * 2002-09-20 2005-10-05 Arrow Therapeutics Ltd Derivados de benzodiazaepina y composiciones farmaceuticas que los contienen.
GB0406282D0 (en) * 2004-03-19 2004-04-21 Arrow Therapeutics Ltd Therapeutic compounds

Also Published As

Publication number Publication date
AU2007321977A1 (en) 2008-05-29
EP2094308B1 (de) 2011-01-12
PL2094308T3 (pl) 2011-06-30
ES2359856T3 (es) 2011-05-27
US20100056500A1 (en) 2010-03-04
ATE494896T1 (de) 2011-01-15
JP2010510311A (ja) 2010-04-02
RU2009123536A (ru) 2010-12-27
WO2008063634A1 (en) 2008-05-29
CA2669705A1 (en) 2008-05-29
MX2009005368A (es) 2009-06-05
KR20090087079A (ko) 2009-08-14
EP2094308A1 (de) 2009-09-02
PT2094308E (pt) 2011-04-14
BRPI0719096A2 (pt) 2013-12-03
CN101553258A (zh) 2009-10-07

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