DE602007010147D1 - Azatricyclische verbindungen und deren verwendung - Google Patents

Azatricyclische verbindungen und deren verwendung

Info

Publication number
DE602007010147D1
DE602007010147D1 DE602007010147T DE602007010147T DE602007010147D1 DE 602007010147 D1 DE602007010147 D1 DE 602007010147D1 DE 602007010147 T DE602007010147 T DE 602007010147T DE 602007010147 T DE602007010147 T DE 602007010147T DE 602007010147 D1 DE602007010147 D1 DE 602007010147D1
Authority
DE
Germany
Prior art keywords
compounds
azatricyclic
azatricyclic compounds
antibacterials
containing compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007010147T
Other languages
English (en)
Inventor
Gerald Brooks
Timothy James Miles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE602007010147D1 publication Critical patent/DE602007010147D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE602007010147T 2006-07-03 2007-07-03 Azatricyclische verbindungen und deren verwendung Active DE602007010147D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0613208.8A GB0613208D0 (en) 2006-07-03 2006-07-03 Compounds
PCT/EP2007/056664 WO2008003690A1 (en) 2006-07-03 2007-07-03 Azatricyclic compounds and their use

Publications (1)

Publication Number Publication Date
DE602007010147D1 true DE602007010147D1 (de) 2010-12-09

Family

ID=36888558

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007010147T Active DE602007010147D1 (de) 2006-07-03 2007-07-03 Azatricyclische verbindungen und deren verwendung

Country Status (7)

Country Link
US (1) US20100004230A1 (de)
EP (1) EP2041145B1 (de)
JP (1) JP2009541456A (de)
AT (1) ATE486079T1 (de)
DE (1) DE602007010147D1 (de)
GB (1) GB0613208D0 (de)
WO (1) WO2008003690A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006012535D1 (de) * 2005-10-21 2010-04-08 Glaxo Group Ltd Peri-kondensierte tricyclische verbindungen verwendbar als antibakterielle mittel
ATE465163T1 (de) 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
TW200831517A (en) * 2006-12-15 2008-08-01 Astrazeneca Ab Chemical compounds
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
KR101567096B1 (ko) * 2007-04-20 2015-11-06 글락소 그룹 리미티드 항균제로서의 트리시클릭 질소 함유 화합물
WO2009104147A2 (en) 2008-02-20 2009-08-27 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
JP2011529960A (ja) 2008-08-04 2011-12-15 アクテリオン ファーマシューティカルズ リミテッド 三環式アルキルアミノメチルオキサゾリジノン誘導体
PT2344495E (pt) 2008-10-07 2015-04-01 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
SI2376497T1 (sl) 2008-12-12 2014-01-31 Actelion Pharmaceuticals Ltd. Derivati 5-amino-2-(1-hidroksi-etil)-tetrahidropirana
CN101870653B (zh) * 2009-04-23 2013-07-10 上海合全药业有限公司 一种2-甲基-3-氟-6-硝基苯甲酸的合成方法
KR101891834B1 (ko) 2009-12-18 2018-09-28 바실리어 파마슈티카 아게 트리시클릭 항생제
US9321788B2 (en) 2011-06-17 2016-04-26 Basilea Pharmaceutica Ag Tricyclic antibiotics
WO2013038374A1 (en) 2011-09-16 2013-03-21 Actelion Pharmaceuticals Ltd Process for manufacturing a synthetic intermediate
TW201326180A (zh) 2011-11-30 2013-07-01 Actelion Pharmaceuticals Ltd ３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素
EA031589B1 (ru) 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
TWI773118B (zh) 2016-02-12 2022-08-01 美商細胞動力學股份有限公司 四氫異喹啉衍生物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1394373A (en) * 1972-05-17 1975-05-14 Pfizer Ltd Control of plant diseases
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
WO2002008224A1 (en) 2000-07-26 2002-01-31 Smithkline Beecham P.L.C. Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
GB0031088D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
WO2003064421A1 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine derivatives
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
GB0217294D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
AR042486A1 (es) 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
DE10316081A1 (de) 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
FR2872164B1 (fr) 2004-06-29 2006-11-17 Aventis Pharma Sa Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US20070161627A1 (en) 2004-08-09 2007-07-12 Miller William H Antibacterial agents
DE102004041163A1 (de) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006038172A1 (en) 2004-10-05 2006-04-13 Actelion Pharmaceuticals Ltd New piperidine antibiotics
WO2006137485A1 (ja) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
DE602006012535D1 (de) * 2005-10-21 2010-04-08 Glaxo Group Ltd Peri-kondensierte tricyclische verbindungen verwendbar als antibakterielle mittel
ATE465163T1 (de) * 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
US7709483B2 (en) * 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) * 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
GB0613208D0 (en) 2006-08-09
WO2008003690A1 (en) 2008-01-10
EP2041145A1 (de) 2009-04-01
ATE486079T1 (de) 2010-11-15
EP2041145B1 (de) 2010-10-27
JP2009541456A (ja) 2009-11-26
US20100004230A1 (en) 2010-01-07

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