DE602007008385D1 - Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgaris - Google Patents
Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgarisInfo
- Publication number
- DE602007008385D1 DE602007008385D1 DE602007008385T DE602007008385T DE602007008385D1 DE 602007008385 D1 DE602007008385 D1 DE 602007008385D1 DE 602007008385 T DE602007008385 T DE 602007008385T DE 602007008385 T DE602007008385 T DE 602007008385T DE 602007008385 D1 DE602007008385 D1 DE 602007008385D1
- Authority
- DE
- Germany
- Prior art keywords
- vpa
- acne vulgaris
- valproic acid
- medium
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical compound CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title abstract 8
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract 3
- 206010000496 acne Diseases 0.000 title abstract 3
- 229960000604 valproic acid Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 abstract 3
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960005280 isotretinoin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000009097 single-agent therapy Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06006847A EP1839656A1 (en) | 2006-03-31 | 2006-03-31 | Use of valproic acid for the topical treatment of mild to moderate acne vulgaris |
| PCT/EP2007/002201 WO2007112832A1 (en) | 2006-03-31 | 2007-03-13 | Use of valproic acid for the topical treatment of mild to moderate acne vulgaris |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007008385D1 true DE602007008385D1 (de) | 2010-09-23 |
Family
ID=36498743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007008385T Active DE602007008385D1 (de) | 2006-03-31 | 2007-03-13 | Verwendung von valproinsäure zur topischen behandlung von leichter bis mittelschwerer akne vulgaris |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090186809A1 (https=) |
| EP (2) | EP1839656A1 (https=) |
| JP (1) | JP2009534306A (https=) |
| AT (1) | ATE476972T1 (https=) |
| DE (1) | DE602007008385D1 (https=) |
| WO (1) | WO2007112832A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492438B2 (en) * | 2002-04-26 | 2013-07-23 | Asan Laboratories Company (Cayman), Limited | Treatment skin disorders |
| EP1491188A1 (en) * | 2003-06-25 | 2004-12-29 | G2M Cancer Drugs AG | Topical use of valproic acid for the prevention or treatment of skin disorders |
| JP5156392B2 (ja) | 2005-02-03 | 2013-03-06 | トポターゲット ユーケー リミテッド | Hdac阻害剤を用いる併用療法 |
| ATE542527T1 (de) | 2005-05-13 | 2012-02-15 | Topotarget Uk Ltd | Pharmazeutische formulierungen von hdac-hemmern |
| WO2007054719A2 (en) | 2005-11-10 | 2007-05-18 | Topotarget Uk Limited | Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent |
| US8642809B2 (en) * | 2007-09-25 | 2014-02-04 | Topotarget Uk Ltd. | Methods of synthesis of certain hydroxamic acid compounds |
| ES2536208T3 (es) * | 2008-03-07 | 2015-05-21 | Onxeo Dk, Branch Of Onxeo S.A., France | Métodos de tratamiento que emplean infusión continua prolongada de Belinostat |
| WO2010077642A1 (en) | 2008-12-08 | 2010-07-08 | Northwestern University | Method of modulating hsf-1 |
| GB0900555D0 (en) * | 2009-01-14 | 2009-02-11 | Topotarget As | New methods |
| AU2011213694B2 (en) * | 2010-02-05 | 2014-05-29 | Sunny Pharmtech, Inc. | Treatment skin disorders |
| KR101733189B1 (ko) * | 2010-10-06 | 2017-05-08 | (주)아모레퍼시픽 | 손톱 또는 발톱 성장 촉진용 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1491188A1 (en) * | 2003-06-25 | 2004-12-29 | G2M Cancer Drugs AG | Topical use of valproic acid for the prevention or treatment of skin disorders |
| DK1591109T3 (da) * | 2004-04-30 | 2008-10-06 | Topotarget Germany Ag | Formulering, der omfatter histondeacetylaseinhibitorer, der udviser tofaset frigivelse |
| SI1776358T1 (sl) * | 2004-07-28 | 2009-10-31 | Janssen Pharmaceutica Nv | Substituirani propenil piperazinski derivati kot novi inhibitorji histon-deacetilaze |
-
2006
- 2006-03-31 EP EP06006847A patent/EP1839656A1/en not_active Withdrawn
-
2007
- 2007-03-13 JP JP2009501893A patent/JP2009534306A/ja not_active Withdrawn
- 2007-03-13 US US12/295,359 patent/US20090186809A1/en not_active Abandoned
- 2007-03-13 EP EP07711939A patent/EP2001458B1/en not_active Not-in-force
- 2007-03-13 AT AT07711939T patent/ATE476972T1/de not_active IP Right Cessation
- 2007-03-13 DE DE602007008385T patent/DE602007008385D1/de active Active
- 2007-03-13 WO PCT/EP2007/002201 patent/WO2007112832A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20090186809A1 (en) | 2009-07-23 |
| WO2007112832A1 (en) | 2007-10-11 |
| EP2001458A1 (en) | 2008-12-17 |
| EP2001458B1 (en) | 2010-08-11 |
| EP1839656A1 (en) | 2007-10-03 |
| ATE476972T1 (de) | 2010-08-15 |
| JP2009534306A (ja) | 2009-09-24 |
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