DE602006021768D1 - Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands - Google Patents
Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustandsInfo
- Publication number
- DE602006021768D1 DE602006021768D1 DE602006021768T DE602006021768T DE602006021768D1 DE 602006021768 D1 DE602006021768 D1 DE 602006021768D1 DE 602006021768 T DE602006021768 T DE 602006021768T DE 602006021768 T DE602006021768 T DE 602006021768T DE 602006021768 D1 DE602006021768 D1 DE 602006021768D1
- Authority
- DE
- Germany
- Prior art keywords
- prognosis
- diagnosis
- lysophosphatidylcholin
- detection
- systemic inflammation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title abstract 2
- 230000009885 systemic effect Effects 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72183305P | 2005-09-28 | 2005-09-28 | |
US76291106P | 2006-01-27 | 2006-01-27 | |
US84140706P | 2006-08-30 | 2006-08-30 | |
PCT/US2006/038177 WO2007038758A2 (en) | 2005-09-28 | 2006-09-27 | Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006021768D1 true DE602006021768D1 (de) | 2011-06-16 |
Family
ID=37900497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006021768T Active DE602006021768D1 (de) | 2005-09-28 | 2006-09-27 | Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands |
Country Status (10)
Country | Link |
---|---|
US (2) | US8183050B2 (de) |
EP (1) | EP1940231B1 (de) |
JP (1) | JP5183480B2 (de) |
KR (1) | KR101281298B1 (de) |
AT (1) | ATE507720T1 (de) |
AU (1) | AU2006294481B2 (de) |
BR (1) | BRPI0616720A2 (de) |
CA (1) | CA2623523C (de) |
DE (1) | DE602006021768D1 (de) |
WO (1) | WO2007038758A2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0609302A2 (pt) | 2005-04-15 | 2011-10-11 | Becton Dickinson Co | métodos para prever o desenvolvimento de sepse e para diagnosticar sepse em um indivìduo a ser testado, microarranjo, kit para prever o desenvolvimento de sepse em um indivìduo a ser testado, produto de programa de computador, computador, sistema de computador para determinar se um indivìduo é susceptìvel de desenvolver sepse, sinal digital embutido em uma onda portadora, e, interface gráfica de usuário para determinar se um indivìduo é susceptìvel de desenvolver sepse |
DE602006021768D1 (de) | 2005-09-28 | 2011-06-16 | Dickinson & Co | Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands |
US20090104605A1 (en) * | 2006-12-14 | 2009-04-23 | Gary Siuzdak | Diagnosis of sepsis |
US8494871B2 (en) * | 2007-07-13 | 2013-07-23 | Koninklijke Philips N.V. | Decision support system for acute dynamic diseases |
EP2247775B1 (de) * | 2008-01-28 | 2012-12-19 | National University of Singapore | Methode de génération d'un modèle de classification |
WO2009126380A2 (en) * | 2008-03-05 | 2009-10-15 | Singulex, Inc. | Methods and compositions for highly sensitive detection of molecules |
WO2009123737A2 (en) * | 2008-04-03 | 2009-10-08 | Becton, Dickinson And Company | Advanced detection of sepsis |
CN103760220A (zh) | 2009-04-10 | 2014-04-30 | 佳能株式会社 | 形成目标构成物的二维分布图像的方法 |
CA2762612A1 (en) | 2009-06-08 | 2010-12-16 | Singulex, Inc. | Highly sensitive biomarker panels |
US8600556B2 (en) * | 2009-06-22 | 2013-12-03 | Johnson Controls Technology Company | Smart building manager |
US8417541B1 (en) * | 2009-08-27 | 2013-04-09 | Cerner Innovation, Inc. | Multi-stage model for predicting probabilities of mortality in adult critically ill patients |
EP2339352A1 (de) | 2009-12-28 | 2011-06-29 | BIOCRATES Life Sciences AG | Verwendung endogener Metaboliten zur frühen Sepsiserkennung |
ITRM20100121A1 (it) * | 2010-03-18 | 2011-09-19 | Univ Pisa | Marcatori molecolari per infezioni delle vie urinarie. |
WO2011140484A1 (en) | 2010-05-06 | 2011-11-10 | Singulex, Inc | Methods for diagnosing, staging, predicting risk for developing and identifying treatment responders for rheumatoid arthritis |
US8904511B1 (en) * | 2010-08-23 | 2014-12-02 | Amazon Technologies, Inc. | Virtual firewalls for multi-tenant distributed services |
US9336302B1 (en) | 2012-07-20 | 2016-05-10 | Zuci Realty Llc | Insight and algorithmic clustering for automated synthesis |
US20150285805A1 (en) | 2012-11-05 | 2015-10-08 | Ospedale San Raffaele S.R.L. | Biomarkers of multiple myeloma development and progression |
WO2014150329A1 (en) * | 2013-03-14 | 2014-09-25 | University Of Georgia Research Foundation, Inc. | Lipid biomarkers of addiction and relapse risk |
CN104458708A (zh) * | 2013-09-12 | 2015-03-25 | 中国药科大学 | 一种筛选乙酰胆碱酯酶抑制剂高通量筛选方法 |
US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
JP2019511057A (ja) * | 2016-03-23 | 2019-04-18 | ピーチ インテリヘルス,インコーポレイティド | Sirsの予測のための臨床パラメータの使用 |
US11205103B2 (en) | 2016-12-09 | 2021-12-21 | The Research Foundation for the State University | Semisupervised autoencoder for sentiment analysis |
US11959916B2 (en) | 2017-12-26 | 2024-04-16 | Tamio Yamauchi | Method, system, and program for supplying immunodynamics-related information |
KR102446591B1 (ko) * | 2018-12-27 | 2022-09-22 | 고리츠다이가쿠호징 나라켕리츠 이카다이가쿠 | 간질성 방광염의 진단 방법 |
US20220146527A1 (en) * | 2019-09-17 | 2022-05-12 | Chang Gung University | Method of creating characteristic profiles of mass spectra and identification model for analyzing and identifying features of microorganisms |
KR102259533B1 (ko) * | 2021-01-04 | 2021-06-02 | 주식회사 아리바이오 | Lpc와 pct를 조합하는 패혈증 진단용 바이오마커 조성물 및 이를 이용한 진단방법 |
CN113189115B (zh) * | 2021-05-17 | 2022-07-08 | 中国矿业大学 | 一种温度场测量及焊接缺陷在线监测装置及监测方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (de) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimäre Rezeptoren durch Verbindung und Expression von DNS |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
JPH05229993A (ja) | 1991-12-13 | 1993-09-07 | Fujirebio Inc | トリフェニルメタン誘導体 |
US6190872B1 (en) * | 1994-05-06 | 2001-02-20 | Gus J. Slotman | Method for identifying and monitoring patients at risk for systemic inflammatory conditions and apparatus for use in this method |
JP3436444B2 (ja) * | 1995-07-21 | 2003-08-11 | ヤマサ醤油株式会社 | 酸化hdlの測定法及びキット |
US6248553B1 (en) * | 1998-10-22 | 2001-06-19 | Atairgin Technologies, Inc. | Enzyme method for detecting lysophospholipids and phospholipids and for detecting and correlating conditions associated with altered levels of lysophospholipids |
JP2002017938A (ja) | 2000-07-07 | 2002-01-22 | Toyo Kogyo Kk | 脛当て |
US7465555B2 (en) | 2002-04-02 | 2008-12-16 | Becton, Dickinson And Company | Early detection of sepsis |
US7015022B2 (en) | 2002-06-07 | 2006-03-21 | University Of Medicine & Dentistry Of New Jersey | Mammalian catalase-dependent oxidation processes and methods for stimulating oxidative activities |
CA2505921A1 (en) | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
MXPA05005072A (es) | 2002-11-12 | 2005-07-22 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
JP2006515670A (ja) | 2002-11-12 | 2006-06-01 | ベクトン,ディッキンソン アンド カンパニー | バイオマーカープロファイルを用いる敗血症またはsirsの診断 |
US7807696B2 (en) * | 2003-10-07 | 2010-10-05 | The Feinstein Institute For Medical Research | Isoxazole and isothiazole compounds useful in the treatment of inflammation |
DE602006021768D1 (de) | 2005-09-28 | 2011-06-16 | Dickinson & Co | Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands |
WO2009123737A2 (en) | 2008-04-03 | 2009-10-08 | Becton, Dickinson And Company | Advanced detection of sepsis |
-
2006
- 2006-09-27 DE DE602006021768T patent/DE602006021768D1/de active Active
- 2006-09-27 AT AT06825270T patent/ATE507720T1/de not_active IP Right Cessation
- 2006-09-27 BR BRPI0616720-9A patent/BRPI0616720A2/pt not_active Application Discontinuation
- 2006-09-27 JP JP2008533696A patent/JP5183480B2/ja active Active
- 2006-09-27 KR KR1020087010053A patent/KR101281298B1/ko active IP Right Grant
- 2006-09-27 AU AU2006294481A patent/AU2006294481B2/en active Active
- 2006-09-27 CA CA2623523A patent/CA2623523C/en active Active
- 2006-09-27 EP EP06825270A patent/EP1940231B1/de active Active
- 2006-09-27 WO PCT/US2006/038177 patent/WO2007038758A2/en active Application Filing
- 2006-09-28 US US11/541,412 patent/US8183050B2/en active Active
-
2012
- 2012-04-18 US US13/450,228 patent/US20120301910A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2623523A1 (en) | 2007-04-05 |
JP5183480B2 (ja) | 2013-04-17 |
JP2009510450A (ja) | 2009-03-12 |
AU2006294481A1 (en) | 2007-04-05 |
WO2007038758A2 (en) | 2007-04-05 |
BRPI0616720A2 (pt) | 2011-06-28 |
KR101281298B1 (ko) | 2013-07-08 |
US8183050B2 (en) | 2012-05-22 |
US20120301910A1 (en) | 2012-11-29 |
AU2006294481B2 (en) | 2012-12-20 |
CA2623523C (en) | 2019-02-12 |
KR20080068824A (ko) | 2008-07-24 |
WO2007038758A3 (en) | 2007-09-13 |
EP1940231B1 (de) | 2011-05-04 |
ATE507720T1 (de) | 2011-05-15 |
EP1940231A2 (de) | 2008-07-09 |
EP1940231A4 (de) | 2008-12-31 |
US20070111316A1 (en) | 2007-05-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602006021768D1 (de) | Nachweis von lysophosphatidylcholin für die prognose oder diagnose eines systemischen entzündungszustands | |
DE502007000755D1 (de) | Kompressorgehäuse für einen abgasturbolader | |
CY1117784T1 (el) | Μεθοδοι και συνθεσεις για διαγνωση και προγνωση νεφρικης βλαβης και νεφρικης ανεπαρκειας | |
ATE453825T2 (de) | Schraubverbindung für stahlrohre | |
WO2009006347A3 (en) | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes | |
BRPI0615415A2 (pt) | método para melhorar a capacidade de remoção de água de lodo | |
TW200728704A (en) | Apparatus and method for measuring real-time corrosion | |
ATE479044T2 (de) | Schraubverbindung für stahlrohre | |
ATE483825T1 (de) | Zusammensetzungen für die identifizierung von adenoviren | |
CY1111839T1 (el) | Μεθοδος για την διαγνωση της πολλαπλης σκληρυνσης | |
DE602006010956D1 (de) | Magnetische Partikel für die Diagnostik | |
DE502007004793D1 (de) | Ventilanordnung für eine abgasrückführeinrichtung | |
WO2008106648A3 (en) | Immunoassays exhibiting a reduction in prozone phenomena | |
DK1974210T3 (da) | Fremgangsmåde til diagnosticering af polycystisk nyresygdom | |
BRPI0606685A2 (pt) | anticorpos gitr para o diagnóstico de nsclc | |
MX2012001559A (es) | Metodos y composiciones para diagnosticos y pronosticos de lesion renal y falla renal. | |
PL2035835T3 (pl) | Sposoby szybkiej oceny ciężkości urazu | |
DE602006018246D1 (de) | Hydraulischer Kreislauf für schwere Baumaschinen | |
MX2012003168A (es) | Metodos y composiciones para diagnosis y prognosis de lesion renal e insuficiencia renal. | |
WO2017097852A3 (en) | Use of ceramides and lpls in diagnosing cvd | |
DE602006005182D1 (de) | Wälzlager für Hilfsaggregate von Kraftfahrzeugen mit der Fähigkeit Abblättern durch Verspröden zu verhindern | |
WO2007140287A3 (en) | Use of biomarkers of inflammation as indicators of drug efficacy | |
ATE504598T1 (de) | Cspcna-isoform-modifikationen und anwendungen davon | |
DE112007002041A5 (de) | Teststruktur für hoch beschleunigte Elektromigrationstests für dicke Metallisierungssysteme von Festkörpern | |
DE602006021254D1 (de) | Betriebsanzeigegerät für Industriefahrzeuge |