DE602006019135D1 - Glucoseisomerase-mutanten, deren verwendung und die dafür codierenden dnas - Google Patents
Glucoseisomerase-mutanten, deren verwendung und die dafür codierenden dnasInfo
- Publication number
- DE602006019135D1 DE602006019135D1 DE602006019135T DE602006019135T DE602006019135D1 DE 602006019135 D1 DE602006019135 D1 DE 602006019135D1 DE 602006019135 T DE602006019135 T DE 602006019135T DE 602006019135 T DE602006019135 T DE 602006019135T DE 602006019135 D1 DE602006019135 D1 DE 602006019135D1
- Authority
- DE
- Germany
- Prior art keywords
- recombinant
- glucose
- amino acid
- mutanes
- glucoseisomerase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 108700040099 Xylose isomerases Proteins 0.000 title abstract 4
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 230000003197 catalytic effect Effects 0.000 abstract 2
- 229930091371 Fructose Natural products 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 241001137871 Thermoanaerobacterium saccharolyticum Species 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 235000019534 high fructose corn syrup Nutrition 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2005101236065A CN1966679B (zh) | 2005-11-18 | 2005-11-18 | 葡萄糖异构酶突变体、其应用以及编码该突变体的dna |
| PCT/CN2006/002901 WO2007056930A1 (fr) | 2005-11-18 | 2006-10-30 | Mutants de glucose isomerase, utilisation mutants et adn codant pour ces mutants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006019135D1 true DE602006019135D1 (de) | 2011-02-03 |
Family
ID=38048287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006019135T Active DE602006019135D1 (de) | 2005-11-18 | 2006-10-30 | Glucoseisomerase-mutanten, deren verwendung und die dafür codierenden dnas |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7704719B2 (de) |
| EP (1) | EP1956083B1 (de) |
| JP (1) | JP4955692B2 (de) |
| CN (1) | CN1966679B (de) |
| AT (1) | ATE492634T1 (de) |
| DE (1) | DE602006019135D1 (de) |
| WO (1) | WO2007056930A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088467A2 (en) | 2010-12-22 | 2012-06-28 | Mascoma Corporation | Genetically modified clostridium thermocellum engineered to ferment xylose |
| CN102443578B (zh) * | 2011-12-08 | 2013-10-16 | 江南大学 | 一种葡萄糖异构酶突变体及其应用 |
| CN104745563A (zh) * | 2015-03-05 | 2015-07-01 | 浙江工业大学 | 葡萄糖异构酶、基因、突变体、工程菌及应用 |
| JP7325335B2 (ja) | 2017-05-05 | 2023-08-14 | シーレクター ゲーエムベーハー | グルコースイソメラーゼ |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0351029B1 (de) | 1988-07-15 | 2002-03-06 | Genencor International, Inc. | Glucose-Isomerase-Enzyme und deren Verwendung |
| DE69133632D1 (de) | 1990-01-04 | 2010-05-27 | Danisco Us Inc | Glukose-Isomerasen mit geänderter Substratspezifität |
| US5656497A (en) | 1994-09-06 | 1997-08-12 | Michigan State University | Gene encoding hyperthermostable xylose isomerase from Thermotoga neapolitana |
| CN1088108C (zh) * | 1997-09-30 | 2002-07-24 | 中国科学技术大学 | 一种葡萄糖异构酶的247位单突变体酶和138,247位双突变体酶及其构建方法 |
| SE9901298D0 (sv) * | 1999-04-09 | 1999-04-09 | Forskarpatent I Syd Ab | Xylose isomerase with improved kinetic properties |
| JP2000333684A (ja) * | 1999-05-26 | 2000-12-05 | Novo Nordisk As | グルコースイソメラーゼ活性を有するポリペプチド及びそれをコードする核酸 |
| CN1693476A (zh) | 2004-05-08 | 2005-11-09 | 张骏 | 一种精液果糖测定新方法及用于该方法的葡萄糖异构酶突变体 |
| CN1693473A (zh) * | 2004-05-08 | 2005-11-09 | 张骏 | 果葡糖浆制备新方法与耐高温葡萄糖异构酶突变体 |
| CN1702172B (zh) | 2004-05-26 | 2011-12-07 | 百瑞全球有限公司 | 葡萄糖异构酶突变体 |
| CN1743454A (zh) | 2004-09-02 | 2006-03-08 | 百瑞全球有限公司 | 葡萄糖异构酶突变体及其应用 |
-
2005
- 2005-11-18 CN CN2005101236065A patent/CN1966679B/zh active Active
-
2006
- 2006-10-30 JP JP2008540429A patent/JP4955692B2/ja active Active
- 2006-10-30 US US12/093,859 patent/US7704719B2/en active Active
- 2006-10-30 WO PCT/CN2006/002901 patent/WO2007056930A1/zh active Application Filing
- 2006-10-30 EP EP06805105A patent/EP1956083B1/de active Active
- 2006-10-30 AT AT06805105T patent/ATE492634T1/de not_active IP Right Cessation
- 2006-10-30 DE DE602006019135T patent/DE602006019135D1/de active Active
-
2010
- 2010-03-15 US US12/723,918 patent/US8067561B2/en active Active
- 2010-03-15 US US12/723,833 patent/US7923222B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4955692B2 (ja) | 2012-06-20 |
| CN1966679A (zh) | 2007-05-23 |
| EP1956083B1 (de) | 2010-12-22 |
| CN1966679B (zh) | 2011-08-17 |
| US20100227365A1 (en) | 2010-09-09 |
| US20080305529A1 (en) | 2008-12-11 |
| US20100228016A1 (en) | 2010-09-09 |
| US7704719B2 (en) | 2010-04-27 |
| US8067561B2 (en) | 2011-11-29 |
| ATE492634T1 (de) | 2011-01-15 |
| EP1956083A1 (de) | 2008-08-13 |
| US7923222B2 (en) | 2011-04-12 |
| JP2009515536A (ja) | 2009-04-16 |
| EP1956083A4 (de) | 2009-02-25 |
| WO2007056930A1 (fr) | 2007-05-24 |
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